Identification
HMDB Protein ID CDBP02787
Secondary Accession Numbers Not Available
Name C-C motif chemokine 28
Description Not Available
Synonyms
  1. MEC
  2. Mucosae-associated epithelial chemokine
  3. Protein CCK1
  4. Small-inducible cytokine A28
Gene Name CCL28
Protein Type Receptor
Biological Properties
General Function Involved in chemokine activity
Specific Function Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner
GO Classification
Component
extracellular region
Function
protein binding
receptor binding
cytokine activity
chemokine activity
binding
Process
immune system process
immune response
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5p12
SNPs CCL28
Gene Sequence
>384 bp
ATGCAGCAGAGAGGACTCGCCATCGTGGCCTTGGCTGTCTGTGCGGCCCTACATGCCTCA
GAAGCCATACTTCCCATTGCCTCCAGCTGTTGCACGGAGGTTTCACATCATATTTCCAGA
AGGCTCCTGGAAAGAGTGAATATGTGTCGCATCCAGAGAGCTGATGGGGATTGTGACTTG
GCTGCTGTCATCCTTCATGTCAAGCGCAGAAGAATCTGTGTCAGCCCGCACAACCATACT
GTTAAGCAGTGGATGAAAGTGCAAGCTGCCAAGAAAAATGGTAAAGGAAATGTTTGCCAC
AGGAAGAAACACCATGGCAAGAGGAACAGTAACAGGGCACATCAGGGGAAACACGAAACA
TACGGCCATAAAACTCCTTATTAG
Protein Properties
Number of Residues 127
Molecular Weight 14279.5
Theoretical pI 10.88
Pfam Domain Function
Signals
  • ["1-19"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>C-C motif chemokine 28
MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDL
AAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHET
YGHKTPY
GenBank ID Protein 12002127
UniProtKB/Swiss-Prot ID Q9NRJ3
UniProtKB/Swiss-Prot Entry Name CCL28_HUMAN
PDB IDs Not Available
GenBank Gene ID AF110384
GeneCard ID CCL28
GenAtlas ID CCL28
HGNC ID HGNC:17700
References
General References Not Available