Identification |
HMDB Protein ID
| CDBP02787 |
Secondary Accession Numbers
| Not Available |
Name
| C-C motif chemokine 28 |
Description
| Not Available |
Synonyms
|
- MEC
- Mucosae-associated epithelial chemokine
- Protein CCK1
- Small-inducible cytokine A28
|
Gene Name
| CCL28 |
Protein Type
| Receptor |
Biological Properties |
General Function
| Involved in chemokine activity |
Specific Function
| Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner |
GO Classification
|
Component |
extracellular region |
Function |
protein binding |
receptor binding |
cytokine activity |
chemokine activity |
binding |
Process |
immune system process |
immune response |
|
Cellular Location
|
- Secreted
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:5 |
Locus
| 5p12 |
SNPs
| CCL28 |
Gene Sequence
|
>384 bp
ATGCAGCAGAGAGGACTCGCCATCGTGGCCTTGGCTGTCTGTGCGGCCCTACATGCCTCA
GAAGCCATACTTCCCATTGCCTCCAGCTGTTGCACGGAGGTTTCACATCATATTTCCAGA
AGGCTCCTGGAAAGAGTGAATATGTGTCGCATCCAGAGAGCTGATGGGGATTGTGACTTG
GCTGCTGTCATCCTTCATGTCAAGCGCAGAAGAATCTGTGTCAGCCCGCACAACCATACT
GTTAAGCAGTGGATGAAAGTGCAAGCTGCCAAGAAAAATGGTAAAGGAAATGTTTGCCAC
AGGAAGAAACACCATGGCAAGAGGAACAGTAACAGGGCACATCAGGGGAAACACGAAACA
TACGGCCATAAAACTCCTTATTAG
|
Protein Properties |
Number of Residues
| 127 |
Molecular Weight
| 14279.5 |
Theoretical pI
| 10.88 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>C-C motif chemokine 28
MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDL
AAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHET
YGHKTPY
|
External Links |
GenBank ID Protein
| 12002127 |
UniProtKB/Swiss-Prot ID
| Q9NRJ3 |
UniProtKB/Swiss-Prot Entry Name
| CCL28_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF110384 |
GeneCard ID
| CCL28 |
GenAtlas ID
| CCL28 |
HGNC ID
| HGNC:17700 |
References |
General References
| Not Available |