| Identification |
|---|
| HMDB Protein ID
| CDBP02767 |
| Secondary Accession Numbers
| Not Available |
| Name
| Macrophage-capping protein |
| Description
| Not Available |
| Synonyms
|
- Actin regulatory protein CAP-G
|
| Gene Name
| CAPG |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in actin binding |
| Specific Function
| Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA |
| GO Classification
|
| Function |
| binding |
| protein binding |
| cytoskeletal protein binding |
| actin binding |
|
| Cellular Location
|
- Nucleus
- Cytoplasm
- Melanosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2p11.2 |
| SNPs
| CAPG |
| Gene Sequence
|
>1047 bp
ATGTACACAGCCATTCCCCAGAGTGGCTCTCCATTCCCAGGCTCAGTGCAGGATCCAGGC
CTGCATGTGTGGCGGGTGGAGAAGCTGAAGCCGGTGCCTGTGGCGCAAGAGAACCAGGGC
GTCTTCTTCTCGGGGGACTCCTACCTAGTGCTGCACAATGGCCCAGAAGAGGTTTCCCAT
CTGCACCTGTGGATAGGCCAGCAGTCATCCCGGGATGAGCAGGGGGCCTGTGCCGTGCTG
GCTGTGCACCTCAACACGCTGCTGGGAGAGCGGCCTGTGCAGCACCGCGAGGTGCAGGGC
AATGAGTCTGACCTCTTCATGAGCTACTTCCCACGGGGCCTCAAGTACCAGGAAGGTGGT
GTGGAGTCAGCATTTCACAAGACCTCCACAGGAGCCCCAGCTGCCATCAAGAAACTCTAC
CAGGTGAAGGGGAAGAAGAACATCCGTGCCACCGAGCGGGCACTGAACTGGGACAGCTTC
AACACTGGGGACTGCTTCATCCTGGACCTGGGCCAGAACATCTTCGCCTGGTGTGGTGGA
AAGTCCAACATCCTGGAACGCAACAAGGCGAGGGACCTGGCCCTGGCCATCCGGGACAGT
GAGCGACAGGGCAAGGCCCAGGTGGAGATTGTCACTGATGGGGAGGAGCCTGCTGAGATG
ATCCAGGTCCTGGGCCCCAAGCCTGCTCTGAAGGAGGGCAACCCTGAGGAAGACCTCACA
GCTGACAAGGCAAATGCCCAGGCCGCAGCTCTGTATAAGGTCTCTGATGCCACTGGACAG
ATGAACCTGACCAAGGTGGCTGACTCCAGCCCATTTGCCCTTGAACTGCTGATATCTGAT
GACTGCTTTGTGCTGGACAACGGGCTCTGTGGCAAGATCTATATCTGGAAGGGGCGAAAA
GCGAATGAGAAGGAGCGGCAGGCAGCCCTGCAGGTGGCCGAGGGCTTCATCTCGCGCATG
CAGTACGCCCCGAACACTCAGGTGGAGATTCTGCCTCAGGGCCATGAGAGTCCCATCTTC
AAGCAATTTTTCAAGGACTGGAAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 348 |
| Molecular Weight
| 38517.3 |
| Theoretical pI
| 6.18 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Macrophage-capping protein
MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSH
LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG
VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG
KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLT
ADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRK
ANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDWK
|
| External Links |
|---|
| GenBank ID Protein
| 62988741 |
| UniProtKB/Swiss-Prot ID
| P40121 |
| UniProtKB/Swiss-Prot Entry Name
| CAPG_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AC062037 |
| GeneCard ID
| CAPG |
| GenAtlas ID
| CAPG |
| HGNC ID
| HGNC:1474 |
| References |
|---|
| General References
| Not Available |