| Identification |
|---|
| HMDB Protein ID
| CDBP02765 |
| Secondary Accession Numbers
| Not Available |
| Name
| Calcineurin subunit B type 1 |
| Description
| Not Available |
| Synonyms
|
- Protein phosphatase 2B regulatory subunit 1
- Protein phosphatase 3 regulatory subunit B alpha isoform 1
|
| Gene Name
| PPP3R1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2p15 |
| SNPs
| PPP3R1 |
| Gene Sequence
|
>513 bp
ATGGGAAATGAGGCAAGTTATCCTTTGGAAATGTGCTCACACTTTGATGCGGATGAAATT
AAAAGGCTAGGAAAGAGATTTAAGAAGCTTGATTTGGACAATTCTGGTTCTTTGAGTGTG
GAAGAGTTCATGTCTCTGCCTGAGTTACAACAGAATCCTTTAGTACAGCGAGTAATAGAT
ATATTCGACACAGATGGGAATGGAGAAGTAGACTTTAAAGAATTCATTGAGGGCGTCTCT
CAGTTCAGTGTCAAAGGAGATAAGGAGCAGAAATTGAGGTTTGCTTTCCGTATCTATGAC
ATGGATAAAGATGGCTATATTTCCAATGGGGAACTCTTCCAGGTATTGAAGATGATGGTG
GGGAACAATCTGAAAGATACACAGTTACAGCAAATTGTAGACAAAACCATAATAAATGCA
GATAAGGATGGAGATGGAAGAATATCCTTTGAAGAATTCTGTGCTGTTGTAGGTGGCCTA
GATATCCACAAAAAGATGGTGGTAGATGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 170 |
| Molecular Weight
| 19299.8 |
| Theoretical pI
| 4.4 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Calcineurin subunit B type 1
MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID
IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV
GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P63098 |
| UniProtKB/Swiss-Prot Entry Name
| CANB1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| M30773 |
| GeneCard ID
| PPP3R1 |
| GenAtlas ID
| PPP3R1 |
| HGNC ID
| HGNC:9317 |
| References |
|---|
| General References
| Not Available |