Identification |
HMDB Protein ID
| CDBP02762 |
Secondary Accession Numbers
| Not Available |
Name
| Calpain-7 |
Description
| Not Available |
Synonyms
|
- PalB homolog
- PalBH
|
Gene Name
| CAPN7 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in calcium-dependent cysteine-type endopeptidase activity |
Specific Function
| Calcium-regulated non-lysosomal thiol-protease |
GO Classification
|
Component |
cell part |
intracellular |
Function |
endopeptidase activity |
cysteine-type endopeptidase activity |
catalytic activity |
hydrolase activity |
calcium-dependent cysteine-type endopeptidase activity |
peptidase activity |
peptidase activity, acting on l-amino acid peptides |
Process |
metabolic process |
macromolecule metabolic process |
protein metabolic process |
proteolysis |
|
Cellular Location
|
- Nucleus
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:3 |
Locus
| 3p24 |
SNPs
| CAPN7 |
Gene Sequence
|
>2442 bp
ATGGACGCCACAGCACTGGAGCGGGACGCTGTGCAGTTCGCCCGTCTGGCGGTTCAGCGC
GACCACGAAGGCCGCTACTCCGAGGCGGTGTTTTATTACAAGGAAGCTGCACAAGCCTTA
ATTTATGCTGAGATGGCAGGATCAAGCCTAGAAAATATTCAAGAAAAAATAACTGAGTAT
CTGGAAAGAGTTCAAGCTCTACATTCAGCAGTTCAGTCAAAGAGTGCTGATCCTTTGAAG
TCAAAACATCAGTTGGACTTAGAGCGTGCTCATTTCCTTGTTACACAAGCTTTTGATGAA
GATGAAAAAGAGAATGTTGAAGATGCTATAGAATTGTACACAGAAGCTGTGGATCTCTGT
CTGAAAACATCTTATGAAACTGCTGATAAAGTCCTGCAAAATAAACTGAAACAGTTGGCT
CGACAGGCACTAGACAGAGCAGAAGCGCTGAGTGAGCCTTTGACCAAGCCAGTTGGCAAA
ATCAGTTCAACAAGTGTTAAGCCAAAGCCACCTCCAGTGAGAGCACATTTTCCACTGGGC
GCTAATCCCTTCCTTGAAAGACCTCAGTCATTTATAAGTCCTCAGTCATGTGATGCACAA
GGACAGAGATACACAGCAGAAGAAATAGAAGTACTCAGGACAACATCAAAAATAAATGGT
ATAGAATATGTTCCTTTCATGAATGTTGACCTGAGAGAACGTTTTGCCTATCCAATGCCT
TTCTGTGATAGATGGGGCAAGCTACCATTATCACCTAAACAAAAAACTACATTTTCCAAG
TGGGTACGACCAGAAGACCTCACCAACAATCCTACAATGATATATACTGTGTCCAGTTTT
AGCATAAAGCAGACAATAGTATCGGATTGCTCCTTTGTGGCATCACTGGCCATCAGTGCA
GCTTATGAAAGACGTTTTAATAAGAAGTTAATTACCGGCATAATTTACCCTCAAAACAAG
GATGGTGAACCAGAATACAATCCATGTGGGAAGTATATGGTAAAACTTCACCTCAATGGT
GTCCCAAGAAAGGTGATAATTGATGACCAGTTACCTGTTGATCACAAGGGAGAATTGCTC
TGTTCTTATTCCAACAACAAAAGTGAATTATGGGTTTCTCTCATAGAAAAAGCATACATG
AAAGTCATGGGAGGATATGATTTTCCAGGATCCAACTCCAATATTGATCTTCATGCACTG
ACTGGCTGGATACCAGAAAGAATTGCTATGCATTCAGATAGCCAAACTTTCAGTAAGGAT
AATTCTTTCAGAATGCTTTATCAAAGATTTCACAAGGGAGATGTCCTCATCACTGCGTCA
ACTGGAATGATGACAGAAGCTGAAGGAGAGAAGTGGGGTCTGGTTCCCACACACGCATAT
GCTGTTTTGGATATTAGAGAGTTCAAGGGGCTGCGATTTATCCAGTTGAAAAATCCTTGG
AGTCATTTACGTTGGAAAGGAAGATACAGTGAAAATGATGTAAAAAACTGGACTCCAGAG
TTGCAAAAGTATTTAAACTTTGATCCCCGAACAGCTCAGAAAATAGACAACGGAATATTT
TGGATTTCCTGGGATGATCTCTGCCAGTATTATGATGTGATTTATTTGAGTTGGAATCCA
GGTCTTTTTAAAGAATCAACATGTATTCACAGTACTTGGGATGCTAAGCAAGGACCTGTG
AAAGATGCCTATAGCCTGGCCAACAACCCCCAGTACAAACTGGAGGTGCAGTGTCCACAG
GGGGGTGCTGCAGTTTGGGTTTTGCTTAGTAGACACATAACAGACAAGGATGATTTTGCG
AATAATCGAGAATTTATCACAATGGTTGTATACAAGACTGATGGGAAAAAAGTTTATTAC
CCAGCTGACCCACCTCCATACATTGATGGAATTCGAATTAACAGCCCTCATTATTTGACT
AAGATAAAGCTGACCACACCTGGCACCCATACCTTTACATTAGTGGTTTCTCAATATGAA
AAACAGAACACAATCCATTACACGGTTCGGGTATATTCAGCATGCAGCTTTACTTTTTCA
AAGATTCCTTCACCATACACCTTATCAAAACGGATTAATGGAAAGTGGAGTGGTCAGAGT
GCTGGAGGATGTGGAAATTTCCAAGAGACTCACAAAAATAACCCCATCTACCAATTCCAT
ATAGAAAAGACTGGGCCGTTACTGATTGAGCTACGAGGACCAAGGCAATATAGCGTTGGA
TTTGAGGTTGTAACAGTTTCTACTCTAGGAGATCCTGGTCCCCATGGCTTTCTGAGGAAA
TCTAGTGGTGACTATAGGTGTGGGTTTTGCTACCTGGAATTAGAAAATATACCTTCTGGG
ATCTTCAATATCATTCCTAGTACCTTTTTGCCTAAACAAGAAGGACCTTTTTTCTTGGAC
TTTAATAGTATTATCCCCATCAAGATCACACAACTTCAGTGA
|
Protein Properties |
Number of Residues
| 813 |
Molecular Weight
| 92651.6 |
Theoretical pI
| 7.72 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Calpain-7
MDATALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLENIQEKITEY
LERVQALHSAVQSKSADPLKSKHQLDLERAHFLVTQAFDEDEKENVEDAIELYTEAVDLC
LKTSYETADKVLQNKLKQLARQALDRAEALSEPLTKPVGKISSTSVKPKPPPVRAHFPLG
ANPFLERPQSFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMNVDLRERFAYPMP
FCDRWGKLPLSPKQKTTFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISA
AYERRFNKKLITGIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELL
CSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKD
NSFRMLYQRFHKGDVLITASTGMMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPW
SHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVIYLSWNP
GLFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFA
NNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYE
KQNTIHYTVRVYSACSFTFSKIPSPYTLSKRINGKWSGQSAGGCGNFQETHKNNPIYQFH
IEKTGPLLIELRGPRQYSVGFEVVTVSTLGDPGPHGFLRKSSGDYRCGFCYLELENIPSG
IFNIIPSTFLPKQEGPFFLDFNSIIPIKITQLQ
|
External Links |
GenBank ID Protein
| 5102944 |
UniProtKB/Swiss-Prot ID
| Q9Y6W3 |
UniProtKB/Swiss-Prot Entry Name
| CAN7_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB028639 |
GeneCard ID
| CAPN7 |
GenAtlas ID
| CAPN7 |
HGNC ID
| HGNC:1484 |
References |
General References
| Not Available |