Identification
HMDB Protein ID CDBP02762
Secondary Accession Numbers Not Available
Name Calpain-7
Description Not Available
Synonyms
  1. PalB homolog
  2. PalBH
Gene Name CAPN7
Protein Type Enzyme
Biological Properties
General Function Involved in calcium-dependent cysteine-type endopeptidase activity
Specific Function Calcium-regulated non-lysosomal thiol-protease
GO Classification
Component
cell part
intracellular
Function
endopeptidase activity
cysteine-type endopeptidase activity
catalytic activity
hydrolase activity
calcium-dependent cysteine-type endopeptidase activity
peptidase activity
peptidase activity, acting on l-amino acid peptides
Process
metabolic process
macromolecule metabolic process
protein metabolic process
proteolysis
Cellular Location
  1. Nucleus
Pathways
Gene Properties
Chromosome Location Chromosome:3
Locus 3p24
SNPs CAPN7
Gene Sequence
>2442 bp
ATGGACGCCACAGCACTGGAGCGGGACGCTGTGCAGTTCGCCCGTCTGGCGGTTCAGCGC
GACCACGAAGGCCGCTACTCCGAGGCGGTGTTTTATTACAAGGAAGCTGCACAAGCCTTA
ATTTATGCTGAGATGGCAGGATCAAGCCTAGAAAATATTCAAGAAAAAATAACTGAGTAT
CTGGAAAGAGTTCAAGCTCTACATTCAGCAGTTCAGTCAAAGAGTGCTGATCCTTTGAAG
TCAAAACATCAGTTGGACTTAGAGCGTGCTCATTTCCTTGTTACACAAGCTTTTGATGAA
GATGAAAAAGAGAATGTTGAAGATGCTATAGAATTGTACACAGAAGCTGTGGATCTCTGT
CTGAAAACATCTTATGAAACTGCTGATAAAGTCCTGCAAAATAAACTGAAACAGTTGGCT
CGACAGGCACTAGACAGAGCAGAAGCGCTGAGTGAGCCTTTGACCAAGCCAGTTGGCAAA
ATCAGTTCAACAAGTGTTAAGCCAAAGCCACCTCCAGTGAGAGCACATTTTCCACTGGGC
GCTAATCCCTTCCTTGAAAGACCTCAGTCATTTATAAGTCCTCAGTCATGTGATGCACAA
GGACAGAGATACACAGCAGAAGAAATAGAAGTACTCAGGACAACATCAAAAATAAATGGT
ATAGAATATGTTCCTTTCATGAATGTTGACCTGAGAGAACGTTTTGCCTATCCAATGCCT
TTCTGTGATAGATGGGGCAAGCTACCATTATCACCTAAACAAAAAACTACATTTTCCAAG
TGGGTACGACCAGAAGACCTCACCAACAATCCTACAATGATATATACTGTGTCCAGTTTT
AGCATAAAGCAGACAATAGTATCGGATTGCTCCTTTGTGGCATCACTGGCCATCAGTGCA
GCTTATGAAAGACGTTTTAATAAGAAGTTAATTACCGGCATAATTTACCCTCAAAACAAG
GATGGTGAACCAGAATACAATCCATGTGGGAAGTATATGGTAAAACTTCACCTCAATGGT
GTCCCAAGAAAGGTGATAATTGATGACCAGTTACCTGTTGATCACAAGGGAGAATTGCTC
TGTTCTTATTCCAACAACAAAAGTGAATTATGGGTTTCTCTCATAGAAAAAGCATACATG
AAAGTCATGGGAGGATATGATTTTCCAGGATCCAACTCCAATATTGATCTTCATGCACTG
ACTGGCTGGATACCAGAAAGAATTGCTATGCATTCAGATAGCCAAACTTTCAGTAAGGAT
AATTCTTTCAGAATGCTTTATCAAAGATTTCACAAGGGAGATGTCCTCATCACTGCGTCA
ACTGGAATGATGACAGAAGCTGAAGGAGAGAAGTGGGGTCTGGTTCCCACACACGCATAT
GCTGTTTTGGATATTAGAGAGTTCAAGGGGCTGCGATTTATCCAGTTGAAAAATCCTTGG
AGTCATTTACGTTGGAAAGGAAGATACAGTGAAAATGATGTAAAAAACTGGACTCCAGAG
TTGCAAAAGTATTTAAACTTTGATCCCCGAACAGCTCAGAAAATAGACAACGGAATATTT
TGGATTTCCTGGGATGATCTCTGCCAGTATTATGATGTGATTTATTTGAGTTGGAATCCA
GGTCTTTTTAAAGAATCAACATGTATTCACAGTACTTGGGATGCTAAGCAAGGACCTGTG
AAAGATGCCTATAGCCTGGCCAACAACCCCCAGTACAAACTGGAGGTGCAGTGTCCACAG
GGGGGTGCTGCAGTTTGGGTTTTGCTTAGTAGACACATAACAGACAAGGATGATTTTGCG
AATAATCGAGAATTTATCACAATGGTTGTATACAAGACTGATGGGAAAAAAGTTTATTAC
CCAGCTGACCCACCTCCATACATTGATGGAATTCGAATTAACAGCCCTCATTATTTGACT
AAGATAAAGCTGACCACACCTGGCACCCATACCTTTACATTAGTGGTTTCTCAATATGAA
AAACAGAACACAATCCATTACACGGTTCGGGTATATTCAGCATGCAGCTTTACTTTTTCA
AAGATTCCTTCACCATACACCTTATCAAAACGGATTAATGGAAAGTGGAGTGGTCAGAGT
GCTGGAGGATGTGGAAATTTCCAAGAGACTCACAAAAATAACCCCATCTACCAATTCCAT
ATAGAAAAGACTGGGCCGTTACTGATTGAGCTACGAGGACCAAGGCAATATAGCGTTGGA
TTTGAGGTTGTAACAGTTTCTACTCTAGGAGATCCTGGTCCCCATGGCTTTCTGAGGAAA
TCTAGTGGTGACTATAGGTGTGGGTTTTGCTACCTGGAATTAGAAAATATACCTTCTGGG
ATCTTCAATATCATTCCTAGTACCTTTTTGCCTAAACAAGAAGGACCTTTTTTCTTGGAC
TTTAATAGTATTATCCCCATCAAGATCACACAACTTCAGTGA
Protein Properties
Number of Residues 813
Molecular Weight 92651.6
Theoretical pI 7.72
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Calpain-7
MDATALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLENIQEKITEY
LERVQALHSAVQSKSADPLKSKHQLDLERAHFLVTQAFDEDEKENVEDAIELYTEAVDLC
LKTSYETADKVLQNKLKQLARQALDRAEALSEPLTKPVGKISSTSVKPKPPPVRAHFPLG
ANPFLERPQSFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMNVDLRERFAYPMP
FCDRWGKLPLSPKQKTTFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISA
AYERRFNKKLITGIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELL
CSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKD
NSFRMLYQRFHKGDVLITASTGMMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPW
SHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVIYLSWNP
GLFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFA
NNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYE
KQNTIHYTVRVYSACSFTFSKIPSPYTLSKRINGKWSGQSAGGCGNFQETHKNNPIYQFH
IEKTGPLLIELRGPRQYSVGFEVVTVSTLGDPGPHGFLRKSSGDYRCGFCYLELENIPSG
IFNIIPSTFLPKQEGPFFLDFNSIIPIKITQLQ
GenBank ID Protein 5102944
UniProtKB/Swiss-Prot ID Q9Y6W3
UniProtKB/Swiss-Prot Entry Name CAN7_HUMAN
PDB IDs Not Available
GenBank Gene ID AB028639
GeneCard ID CAPN7
GenAtlas ID CAPN7
HGNC ID HGNC:1484
References
General References Not Available