Showing Protein Calumenin (CDBP02749)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02749
Secondary Accession Numbers Not Available
Name Calumenin
Description Not Available
Synonyms
  1. Crocalbin
  2. IEF SSP 9302
Gene Name CALU
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity
GO Classification
Function
metal ion binding
binding
calcium ion binding
ion binding
cation binding
Cellular Location
  1. Melanosome
  2. Secreted
  3. Endoplasmic reticulum lumen
  4. Sarcoplasmic reticulum lumen
Pathways
Gene Properties
Chromosome Location Chromosome:7
Locus 7q32.1
SNPs CALU
Gene Sequence 
>948 bp
ATGGACCTGCGACAGTTTCTTATGTGCCTGTCCCTGTGCACAGCCTTTGCCTTGAGCAAA
CCCACAGAAAAGAAGGACCGTGTACATCATGAGCCTCAGCTCAGTGACAAGGTTCACAAT
GATGCTCAGAGTTTTGATTATGACCATGATGCCTTCTTGGGTGCTGAAGAAGCAAAGACC
TTTGATCAGCTGACACCAGAAGAGAGCAAGGAAAGGCTTGGAAAGATTGTAAGTAAAATA
GATGGCGACAAGGACGGGTTTGTCACTGTGGATGAGCTCAAAGACTGGATTAAATTTGCA
CAAAAGCGCTGGATTTACGAGGATGTAGAGCGACAGTGGAAGGGGCATGACCTCAATGAG
GACGGCCTCGTTTCCTGGGAGGAGTATAAAAATGCCACCTACGGCTACGTTTTAGATGAT
CCAGATCCTGATGATGGATTTAACTATAAACAGATGATGGTTAGAGATGAGCGGAGGTTT
AAAATGGCAGACAAGGATGGAGACCTCATTGCCACCAAGGAGGAGTTCACAGCTTTCCTG
CACCCTGAGGAGTATGACTACATGAAAGATATAGTAGTACAGGAAACAATGGAAGATATA
GATAAGAATGCTGATGGTTTCATTGATCTAGAAGAGTATATTGGTGACATGTACAGCCAT
GATGGGAATACTGATGAGCCAGAATGGGTAAAGACAGAGCGAGAGCAGTTTGTTGAGTTT
CGGGATAAGAACCGTGATGGGAAGATGGACAAGGAAGAGACCAAAGACTGGATCCTTCCC
TCAGACTATGATCATGCAGAGGCAGAAGCCAGGCACCTGGTCTATGAATCAGACCAAAAC
AAGGATGGCAAGCTTACCAAGGAGGAGATCGTTGACAAGTATGACTTATTTGTTGGCAGC
CAGGCCACAGATTTTGGGGAGGCCTTAGTACGGCATGATGAGTTCTGA
Protein Properties
Number of Residues 315
Molecular Weight 37106.5
Theoretical pI 4.23
Pfam Domain Function Not Available
Signals
  • ["1-19"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Calumenin
MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKT
FDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNE
DGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFL
HPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEF
RDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGS
QATDFGEALVRHDEF
GenBank ID Protein 3153209
UniProtKB/Swiss-Prot ID O43852
UniProtKB/Swiss-Prot Entry Name CALU_HUMAN
PDB IDs Not Available
GenBank Gene ID AF013759
GeneCard ID CALU
GenAtlas ID CALU
HGNC ID HGNC:1458
References
General References Not Available