| Identification |
|---|
| HMDB Protein ID
| CDBP02744 |
| Secondary Accession Numbers
| Not Available |
| Name
| VWFA and cache domain-containing protein 1 |
| Description
| Not Available |
| Synonyms
|
- Cache domain-containing protein 1
|
| Gene Name
| CACHD1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell motility |
| Specific Function
| May regulate voltage-dependent calcium channels |
| GO Classification
|
| Component |
| membrane |
| cell part |
|
| Cellular Location
|
- Membrane
- Single-pass type I membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1p31.3 |
| SNPs
| CACHD1 |
| Gene Sequence
|
>3672 bp
ATGCGGAGGCTGGCGGCCGAGGAGCTGGGGGTCGTCACCATGCAGCGGATATTCAACTCC
TTTGTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAA
ATCCGAGAGAAGTTCAACCGTTACTTGGATGTGGTCAATCGGAACAAGCAAGTTGTAGAA
GCATCCTATACGGCTCACCTAACCTCTCCCCTAACTGCAATTCAAGACTGCTGTACTATC
CCACCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGT
TGTGATCGACTTTCTACTACTGTTAATAGCCGGGCCTTCAATCCAGGACGAGACTTAAAT
TCAGTTCTTGCAGACAACCTGAAATCCAACCCTGGAATTAAGTGGCAATATTTCAGTTCA
GAAGAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAA
CACCGCAGTAGACCCATCTACGTCTCTACAGTCCGGCCGCAGTCAAAGCACATAGTAGTG
ATTCTGGACCACGGGGCTTCAGTCACAGACACTCAGCTTCAGATTGCCAAGGACGCTGCT
CAGGTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGAT
ACCGTCCGGACTTGCTCACTAGACCAGTGCTATAAGACCTTCTTGTCTCCAGCCACCAGT
GAGACAAAAAGGAAAATGTCCACCTTTGTTAGCAGCGTGAAGTCTTCAGACAGTCCTACC
CAGCACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACA
AAGTTCCAAGCAAATACAGACATGGTCATCATTTACCTGTCAGCTGGCATTACATCAAAG
GACTCTTCGGAAGAAGATAAAAAAGCGACTCTCCAAGTCATCAATGAAGAAAATAGCTTT
CTAAACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTG
AAAGAGCTGGCTTTTCTGAGGGATCTAGCTGAACAGAATTCAGGGAAGTACGGTGTGCCA
GACCGGATGGCCTTGCCTGTGATTAAGGGCAGCATGATGGTGCTGAATCAGTTGAGCAAC
CTGGAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCC
GTCTTCAGCCTGCCCTTCTCTGATGAGATGGGAGATGGTTTGATAATGACTGTGAGTAAA
CCCTGTTATTTTGGAAACCTACTTCTGGGAATTGTAGGTGTGGACGTGAATCTGGCTTAC
ATTCTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGAC
GACAAAGGATATACACTTATGCACCCATCTCTTACCAGGCCATATTTATTGTCAGAGCCC
CCACTTCATACTGACATCATACATTATGAAAATATTCCAAAATTTGAATTAGTTCGGCAA
AATATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTG
TCTTGGCACATAAACAAGCTGAGAGAAACTGGAAAGGAAGCCTACAATGTTAGCTATGCC
TGGAAGATGGTACAAGACACTTCCTTTATTCTGTGTATTGTGGTGATACAACCAGAAATA
CCTGTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGG
CTGGATCTCCTTGGCCAGCCCAGTGCTTGCCTCCACTTCAAACAGCTGGCAACCCTAGAA
AGTCCCACCATCATGCTGTCTGCTGGCAGCTTTTCCTCCCCCTATGAGCACCTCAGCCAG
CCAGAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTC
ATTGCTAACCCGGGCCTCAAATTCTCTGTCAGAAATGAAGTAATGGCTACCAGCCACGTC
ACAGATGAATGGATGACACAAATGGAAATGAGTAGCCTGAACACTTACATTGTCCGCCGT
TACATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCA
TTTGATCCCACTAGGAGACAATGGTATCTCCATGCAGTAGCTAATCCAGGGTTGATTTCT
TTGACTGGTCCTTACTTAGATGTTGGAGGAGCTGGTTATGTTGTGACAATCAGTCACACA
ATTCATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGAC
TTCACACTCAGATACTTCTACAAAGTTCTGATGGACCTATTACCTGTCTGTAACCAAGAT
GGTGGCAACAAAATAAGGTGCTTCATAATGGAGGACAGGGGTTATCTGGTGGCGCACCCG
ACTCTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAG
CCCCTGGTAGCAAATGATATCCTCAACCACCCCAACTTTGTAAAGAAAAACCTGTGCAAC
AGCTTCAGTGACAGAACGGTCCAGAGGTTTTATAAATTCAACACCAGCCTTGCGGGGGAT
TTGACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGA
ACCAACGCGTTTGTTGGCATTGTCAACGAAACCTGCGACTCTCTTGCCTTCTGTGCCTGC
AGCATGGTGGACCGACTCTGTCTCAACTGTCACCGAATGGAACAAAATGAATGTGAATGT
CCTTGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAAC
CGAAACCCCAGCTGCGAGGTCCACCAGGAGCCGGTGACATACACAGCTATTGACCCTGGC
CTGCAAGATGCTCTTCACCAGTGTGTCAACAGCAGGTGCAGTCAGAGGCTGGAAAGTGGG
GACTGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCAC
CTGGACAAACCCTACTGTGCCCCCCAGAAAGAATGCTTCGGGGGGATTGTGGGAGCCAAA
AGTCCCTACGTTGATGACATGGGAGCAATAGGTGATGAGGTGATCACATTAAACATGATT
AAAAGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTC
CTGGCGGTGTATGCCTACCGCCACCAGATTCATCGCCGGAGCCATCAGCATATGTCTCCT
CTTGCTGCCCAAGAAATGTCAGTGCGTATGTCCAACCTGGAGAATGACAGAGATGAAAGG
GACGACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTC
ATCGAACGACATGCACACAGTCCAGAAAGAAGGCGCCGCTACTGGGGTCGATCAGGAACA
GAAAGTGATCATGGTTACAGCACCATGAGCCCACAGGAGGACAGTGAAAATCCTCCATGC
AACAATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTG
GATACCCCCCCTCAGACTGCTGCCCTACTAAGTCACAAGTTCCACCACTACCGGTCACAC
CACCCTACACTTCATCATAGCCACCACTTACAGGCGGCCGTCACGGTACACACTGTCGAT
GCAGAATGCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 1274 |
| Molecular Weight
| 142288.4 |
| Theoretical pI
| 6.4 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>VWFA and cache domain-containing protein 1
MARQPEEEETAVARARRPPLWLLCLVACWLLGAGAEADFSILDEAQVLASQMRRLAAEEL
GVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTS
PLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKS
NPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVT
DTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTF
VSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKA
TLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIK
GSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLL
GIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHY
ENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSF
ILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAG
SFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQME
MSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVG
GAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFI
MEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQR
FYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLN
CHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCV
NSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPYVDDMGA
IGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVR
MSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTM
SPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRSHHPTLHHSHH
LQAAVTVHTVDAEC
|
| External Links |
|---|
| GenBank ID Protein
| 110578649 |
| UniProtKB/Swiss-Prot ID
| Q5VU97 |
| UniProtKB/Swiss-Prot Entry Name
| CAHD1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| CACHD1 |
| GenAtlas ID
| CACHD1 |
| HGNC ID
| HGNC:29314 |
| References |
|---|
| General References
| Not Available |