Identification
HMDB Protein ID CDBP02741
Secondary Accession Numbers Not Available
Name Cadherin-related family member 4
Description Not Available
Synonyms
  1. Cadherin-like protein 29
Gene Name CDHR4
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Membrane
  2. Single-pass type I membrane protein (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:3
Locus 3p21.31
SNPs CDHR4
Gene Sequence
>2367 bp
ATGGTGCTGCTCAGGCTCCTCGTGTTCCTCTTTGCTCCGGTGGTCTCTGACCTCTGCAGC
CTGCCCTGCTTTATAAATGTCTCTGAGAGCCAGGGCCCTGGCACAGTCCTTCAGTTTTTA
TCCTTCAACTGCTCCTCCTACACGCCCACACCCACCCTGGAGTTGCTCAATGTCCAGCCA
CCCACCACCTTCTTCAACCCACCCAGCTTGGCCAGGTGGCAAGGGACCTATGTGGGCAAG
TTGACCTTGAGCAGCTCTGCTCAGTTGGATGCCCTGATGGTGAACCACTACAAGGTGCAG
CTGAAGTTCACATGTGGCAACCATGTGATGGAGGGCTCACTCTCTGTGGATGTGCAGCGG
GACCTTAGCCATATCCAGTGTGCTGGTCAATTTGCCAGCCCAGCTGGGGAAATGATTCAG
GTGCCAGAGACAGTCACACCTGGGGCTCGGCTGTACACTCTGCTCCTCCCAGGCCTAGAA
CTCCACGGAGCGCAGATGAGCATTATCAGTGCCCAGGACCTGCCACACTTCCCTGGACCT
TTCTCCATCAATGAGCAAGGTTGGCTGCAGGCACCATCCCAGGGCCTCCTAGGCCAGGCT
CAAAAGGTCTTCCAGCTGCAAATCTCAGTGTCCTTTGGACAAAGGCAAAGCTGCCAAGGG
ATGGTGATAGTGAAGGTTTTGCCTGTTCCCTCCAGCCAGGTCTCCTTCCTCGAGCAGGCT
CAGAATATCACCATCCCTGAGAATCTGGCCCCCGGTAGTGAGGTGGTTCAGGTCCAGGCC
CGGGGTGTCGACCTGCGCTATGAAATCCTGTCTCCGGTGCCCAGCCCACTCTTCTCCATT
GGTCGTGCAGACGGTGTGGTCCGGACCACCACGCCCCTAGAGTTAGCTCGCACCTCAGGC
ACCGCGGTCTCCAGGCTGCAGGTGAAGGCCTTTGAGCAGGGCCAGCTGTGGGCCAGTGCC
AAGCTCAATCTCACCATGAATGTGCAGCTGGTCAACCTCTGGCCTCCACGCTGCCTCCCA
GCGCTTCTGGTGTCCCAAATCCCGGAGACTGCACCCGTGGGCACCGTGCTGAATACTCTC
ACTTGCGAAGATCCGGACTCTGTTGGTGCCACCCTGGACTACAAGCTGTGGTTCCGCAGC
TCTTCCAACCCTGCCAGCCTCTGCCTTTATGACAGAGTCCTTGAGGTGAATGCCACACTG
GACTGTGACACTCCTGGAGCCTGCTTCCAGCATGCAGCCTCCATCCTGGTGCTCGATGGT
GGCCAGCCCCAGATGACCACTGAGGTGCCGGTACTGGTGATGGTGACACCCATCAACGAG
TTCTCCCCAGCCTGTGCCCCTCGCACGTTCCGGGTTCAGGAGGATGCGGCGCCCCACACT
CTACTGGGCTCCGTGGTGGGCACGGATATGGATTACCCTCACGACAACATTGAGTACTAC
ACCTCTGGTGGTCCTACCACCTTTGCTGTGGACCGTCTCAGCGGGGAAGTTCACCTCCTG
GGACCTTTGGACTATGAGCAGCAGAGGCTGTACAGGCTCACTGTCCTTGTGATTGACCAT
GGCCAAGACCAGAACCCCAACCATCACCTCTCAGGCTCCTGTACCATTACCATCGAGGTT
GAGGATGTGAATGACCATGCCCCCGAGTGTGAGCCCCCATTTCAGGAACTCACCATCTAT
GCTCCTCTGGGCCGTAGCGTGGAGGTGACCAAGATGTCATGCCAGATCCCTCAGGAGCCA
CAGCGCCTGATCTACTCCTATAGCATCGTGGGAGGGAATAGCCAGAACCGATTCATCCTG
CAAGGGGCCATCCTGGTGCACAGTGACCTTGTGTTGGGGCCGTTCTGGCCAGAGCAGCCC
CGTACCTATGAGCTACTGATCTGTGTGGCCGATGCAGGCCCCTCCACCCCCCACCTCAGC
ACCACAGCCACCATTATTGTGCATCTAGTTCCCCGGAGGGCCAGCACAGTGGCCACCAGC
ACCCACAGAACCACAGTGCCCTCAACGATGACACCCATGCTCGTGACAGACACAGAGGCT
TTCTGGCAGCCACAGCCCTGGTTTGTGGTGGTGTTGACAGCAACTGGTGCTCTTCTCCTC
TTGGCCCTAGGCTGGCTTCTTGGCAGGCTCCTCCAGGGGTTGGCCCAGCTGCTGCAAGCA
CCCAGCAAACCAGCCCAGGCTTTGCTGCTAAACAGCATCCAGGGAACTGAGGGATCCATC
GAGGGTTTCCTGGAGGCACCGAAGATGGAGATGTCCCAGGCACCCAGCAGTGTCATGAGT
CTGCATTTTGATGGCAGAGCACAGGACTCCCGTACCGGAAGAGACTACCTGTTTAACACA
CACACAGGAGCCCGGCGCTGGCTCTGA
Protein Properties
Number of Residues 788
Molecular Weight 85826.6
Theoretical pI 5.13
Pfam Domain Function
Signals
  • ["1-16"]
Transmembrane Regions
  • ["687-707"]
Protein Sequence
>Cadherin-related family member 4
MVLLRLLVFLFAPVVSDLCSLPCFINVSESQGPGTVLQFLSFNCSSYTPTPTLELLNVQP
PTTFFNPPSLARWQGTYVGKLTLSSSAQLDALMVNHYKVQLKFTCGNHVMEGSLSVDVQR
DLSHIQCAGQFASPAGEMIQVPETVTPGARLYTLLLPGLELHGAQMSIISAQDLPHFPGP
FSINEQGWLQAPSQGLLGQAQKVFQLQISVSFGQRQSCQGMVIVKVLPVPSSQVSFLEQA
QNITIPENLAPGSEVVQVQARGVDLRYEILSPVPSPLFSIGRADGVVRTTTPLELARTSG
TAVSRLQVKAFEQGQLWASAKLNLTMNVQLVNLWPPRCLPALLVSQIPETAPVGTVLNTL
TCEDPDSVGATLDYKLWFRSSSNPASLCLYDRVLEVNATLDCDTPGACFQHAASILVLDG
GQPQMTTEVPVLVMVTPINEFSPACAPRTFRVQEDAAPHTLLGSVVGTDMDYPHDNIEYY
TSGGPTTFAVDRLSGEVHLLGPLDYEQQRLYRLTVLVIDHGQDQNPNHHLSGSCTITIEV
EDVNDHAPECEPPFQELTIYAPLGRSVEVTKMSCQIPQEPQRLIYSYSIVGGNSQNRFIL
QGAILVHSDLVLGPFWPEQPRTYELLICVADAGPSTPHLSTTATIIVHLVPRRASTVATS
THRTTVPSTMTPMLVTDTEAFWQPQPWFVVVLTATGALLLLALGWLLGRLLQGLAQLLQA
PSKPAQALLLNSIQGTEGSIEGFLEAPKMEMSQAPSSVMSLHFDGRAQDSRTGRDYLFNT
HTGARRWL
GenBank ID Protein 203097724
UniProtKB/Swiss-Prot ID A6H8M9
UniProtKB/Swiss-Prot Entry Name CDHR4_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001007540.2
GeneCard ID CDHR4
GenAtlas ID CDHR4
HGNC ID HGNC:34527
References
General References Not Available