Identification |
HMDB Protein ID
| CDBP02741 |
Secondary Accession Numbers
| Not Available |
Name
| Cadherin-related family member 4 |
Description
| Not Available |
Synonyms
|
- Cadherin-like protein 29
|
Gene Name
| CDHR4 |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Involved in calcium ion binding |
Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types |
GO Classification
|
Component |
membrane |
cell part |
plasma membrane |
Function |
ion binding |
cation binding |
metal ion binding |
binding |
calcium ion binding |
Process |
cell adhesion |
cellular process |
cell-cell adhesion |
homophilic cell adhesion |
|
Cellular Location
|
- Membrane
- Single-pass type I membrane protein (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:3 |
Locus
| 3p21.31 |
SNPs
| CDHR4 |
Gene Sequence
|
>2367 bp
ATGGTGCTGCTCAGGCTCCTCGTGTTCCTCTTTGCTCCGGTGGTCTCTGACCTCTGCAGC
CTGCCCTGCTTTATAAATGTCTCTGAGAGCCAGGGCCCTGGCACAGTCCTTCAGTTTTTA
TCCTTCAACTGCTCCTCCTACACGCCCACACCCACCCTGGAGTTGCTCAATGTCCAGCCA
CCCACCACCTTCTTCAACCCACCCAGCTTGGCCAGGTGGCAAGGGACCTATGTGGGCAAG
TTGACCTTGAGCAGCTCTGCTCAGTTGGATGCCCTGATGGTGAACCACTACAAGGTGCAG
CTGAAGTTCACATGTGGCAACCATGTGATGGAGGGCTCACTCTCTGTGGATGTGCAGCGG
GACCTTAGCCATATCCAGTGTGCTGGTCAATTTGCCAGCCCAGCTGGGGAAATGATTCAG
GTGCCAGAGACAGTCACACCTGGGGCTCGGCTGTACACTCTGCTCCTCCCAGGCCTAGAA
CTCCACGGAGCGCAGATGAGCATTATCAGTGCCCAGGACCTGCCACACTTCCCTGGACCT
TTCTCCATCAATGAGCAAGGTTGGCTGCAGGCACCATCCCAGGGCCTCCTAGGCCAGGCT
CAAAAGGTCTTCCAGCTGCAAATCTCAGTGTCCTTTGGACAAAGGCAAAGCTGCCAAGGG
ATGGTGATAGTGAAGGTTTTGCCTGTTCCCTCCAGCCAGGTCTCCTTCCTCGAGCAGGCT
CAGAATATCACCATCCCTGAGAATCTGGCCCCCGGTAGTGAGGTGGTTCAGGTCCAGGCC
CGGGGTGTCGACCTGCGCTATGAAATCCTGTCTCCGGTGCCCAGCCCACTCTTCTCCATT
GGTCGTGCAGACGGTGTGGTCCGGACCACCACGCCCCTAGAGTTAGCTCGCACCTCAGGC
ACCGCGGTCTCCAGGCTGCAGGTGAAGGCCTTTGAGCAGGGCCAGCTGTGGGCCAGTGCC
AAGCTCAATCTCACCATGAATGTGCAGCTGGTCAACCTCTGGCCTCCACGCTGCCTCCCA
GCGCTTCTGGTGTCCCAAATCCCGGAGACTGCACCCGTGGGCACCGTGCTGAATACTCTC
ACTTGCGAAGATCCGGACTCTGTTGGTGCCACCCTGGACTACAAGCTGTGGTTCCGCAGC
TCTTCCAACCCTGCCAGCCTCTGCCTTTATGACAGAGTCCTTGAGGTGAATGCCACACTG
GACTGTGACACTCCTGGAGCCTGCTTCCAGCATGCAGCCTCCATCCTGGTGCTCGATGGT
GGCCAGCCCCAGATGACCACTGAGGTGCCGGTACTGGTGATGGTGACACCCATCAACGAG
TTCTCCCCAGCCTGTGCCCCTCGCACGTTCCGGGTTCAGGAGGATGCGGCGCCCCACACT
CTACTGGGCTCCGTGGTGGGCACGGATATGGATTACCCTCACGACAACATTGAGTACTAC
ACCTCTGGTGGTCCTACCACCTTTGCTGTGGACCGTCTCAGCGGGGAAGTTCACCTCCTG
GGACCTTTGGACTATGAGCAGCAGAGGCTGTACAGGCTCACTGTCCTTGTGATTGACCAT
GGCCAAGACCAGAACCCCAACCATCACCTCTCAGGCTCCTGTACCATTACCATCGAGGTT
GAGGATGTGAATGACCATGCCCCCGAGTGTGAGCCCCCATTTCAGGAACTCACCATCTAT
GCTCCTCTGGGCCGTAGCGTGGAGGTGACCAAGATGTCATGCCAGATCCCTCAGGAGCCA
CAGCGCCTGATCTACTCCTATAGCATCGTGGGAGGGAATAGCCAGAACCGATTCATCCTG
CAAGGGGCCATCCTGGTGCACAGTGACCTTGTGTTGGGGCCGTTCTGGCCAGAGCAGCCC
CGTACCTATGAGCTACTGATCTGTGTGGCCGATGCAGGCCCCTCCACCCCCCACCTCAGC
ACCACAGCCACCATTATTGTGCATCTAGTTCCCCGGAGGGCCAGCACAGTGGCCACCAGC
ACCCACAGAACCACAGTGCCCTCAACGATGACACCCATGCTCGTGACAGACACAGAGGCT
TTCTGGCAGCCACAGCCCTGGTTTGTGGTGGTGTTGACAGCAACTGGTGCTCTTCTCCTC
TTGGCCCTAGGCTGGCTTCTTGGCAGGCTCCTCCAGGGGTTGGCCCAGCTGCTGCAAGCA
CCCAGCAAACCAGCCCAGGCTTTGCTGCTAAACAGCATCCAGGGAACTGAGGGATCCATC
GAGGGTTTCCTGGAGGCACCGAAGATGGAGATGTCCCAGGCACCCAGCAGTGTCATGAGT
CTGCATTTTGATGGCAGAGCACAGGACTCCCGTACCGGAAGAGACTACCTGTTTAACACA
CACACAGGAGCCCGGCGCTGGCTCTGA
|
Protein Properties |
Number of Residues
| 788 |
Molecular Weight
| 85826.6 |
Theoretical pI
| 5.13 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Cadherin-related family member 4
MVLLRLLVFLFAPVVSDLCSLPCFINVSESQGPGTVLQFLSFNCSSYTPTPTLELLNVQP
PTTFFNPPSLARWQGTYVGKLTLSSSAQLDALMVNHYKVQLKFTCGNHVMEGSLSVDVQR
DLSHIQCAGQFASPAGEMIQVPETVTPGARLYTLLLPGLELHGAQMSIISAQDLPHFPGP
FSINEQGWLQAPSQGLLGQAQKVFQLQISVSFGQRQSCQGMVIVKVLPVPSSQVSFLEQA
QNITIPENLAPGSEVVQVQARGVDLRYEILSPVPSPLFSIGRADGVVRTTTPLELARTSG
TAVSRLQVKAFEQGQLWASAKLNLTMNVQLVNLWPPRCLPALLVSQIPETAPVGTVLNTL
TCEDPDSVGATLDYKLWFRSSSNPASLCLYDRVLEVNATLDCDTPGACFQHAASILVLDG
GQPQMTTEVPVLVMVTPINEFSPACAPRTFRVQEDAAPHTLLGSVVGTDMDYPHDNIEYY
TSGGPTTFAVDRLSGEVHLLGPLDYEQQRLYRLTVLVIDHGQDQNPNHHLSGSCTITIEV
EDVNDHAPECEPPFQELTIYAPLGRSVEVTKMSCQIPQEPQRLIYSYSIVGGNSQNRFIL
QGAILVHSDLVLGPFWPEQPRTYELLICVADAGPSTPHLSTTATIIVHLVPRRASTVATS
THRTTVPSTMTPMLVTDTEAFWQPQPWFVVVLTATGALLLLALGWLLGRLLQGLAQLLQA
PSKPAQALLLNSIQGTEGSIEGFLEAPKMEMSQAPSSVMSLHFDGRAQDSRTGRDYLFNT
HTGARRWL
|
External Links |
GenBank ID Protein
| 203097724 |
UniProtKB/Swiss-Prot ID
| A6H8M9 |
UniProtKB/Swiss-Prot Entry Name
| CDHR4_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_001007540.2 |
GeneCard ID
| CDHR4 |
GenAtlas ID
| CDHR4 |
HGNC ID
| HGNC:34527 |
References |
General References
| Not Available |