| Identification |
|---|
| HMDB Protein ID
| CDBP02732 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cadherin-related family member 3 |
| Description
| Not Available |
| Synonyms
|
- Cadherin-like protein 28
|
| Gene Name
| CDHR3 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types |
| GO Classification
|
| Component |
| membrane |
| cell part |
| Function |
| metal ion binding |
| binding |
| calcium ion binding |
| ion binding |
| cation binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q22.3 |
| SNPs
| CDHR3 |
| Gene Sequence
|
>2658 bp
ATGCAGGAAGCAATCATTCTCCTGGCTCTCCTGGGTGCCATGTCAGGGGGAGAAGCACTA
CACCTAATCCTCTTACCTGCTACAGGCAATGTGGCAGAGAATTCTCCACCTGGGACTTCA
GTGCACAAGTTTTCTGTGAAGTTATCAGCATCATTGTCACCTGTGATCCCAGGATTTCCC
CAGATAGTCAACTCAAATCCCCTCACTGAAGCTTTTAGGGTGAATTGGCTGTCAGGCACC
TACTTTGAGGTTGTCACCACTGGGATGGAACAACTAGATTTTGAAACAGGACCAAACATA
TTTGATTTGCAGATTTATGTGAAGGATGAGGTTGGTGTCACAGACCTGCAAGTCCTGACT
GTCCAGGTAACAGATGTGAACGAGCCACCTCAGTTTCAAGGCAACTTGGCAGAAGGTCTA
CACCTCTACATAGTAGAAAGAGCAAACCCTGGATTCATTTACCAGGTTGAGGCCTTCGAT
CCAGAAGACACAAGCCGAAACATTCCCCTCAGTTATTTCCTGATTTCTCCCCCAAAGAGC
TTCAGAATGTCTGCTAATGGCACCCTCTTCTCCACAACAGAATTGGACTTTGAAGCAGGA
CACAGAAGTTTCCATCTCATCGTGGAGGTGAGGGACAGTGGAGGCCTCAAAGCCTCCACA
GAGCTCCAGGTGAACATCGTGAACCTCAACGACGAAGTCCCTCGCTTTACCAGCCCGACA
CGAGTGTACACAGTCCTGGAGGAACTGAGTCCAGGAACCATCGTGGCCAATATCACAGCG
GAGGATCCTGATGATGAAGGTTTTCCCAGCCACCTCCTCTACAGCATTACCACTGTTAGC
AAATATTTCATGATAAATCAGTTGACTGGTACAATCCAAGTGGCCCAAAGGATAGACCGA
GATGCAGGTGAATTGAGACAAAATCCCACCATTTCCCTGGAAGTTCTAGTGAAGGACAGA
CCATATGGGGGTCAGGAGAATCGCATCCAGATAACCTTCATTGTGGAAGACGTCAACGAC
AATCCTGCCACATGCCAAAAGTTCACCTTCAGCATTATGGTGCCGGAAAGAACAGCCAAG
GGGACGTTGCTTCTTGACCTAAACAAGTTCTGCTTTGATGATGACAGTGAGGCACCAAAC
AACAGATTCAACTTCACCATGCCATCTGGAGTGGGGAGCGGCAGCAGATTTTTACAGGAT
CCAGCTGGCTCTGGGAAGATTGTGCTGATTGGTGATCTAGACTACGAAAATCCAAGTAAC
CTAGCAGCCGGCAATAAATATACGGTGATAATCCAGGTGCAGGATGTGGCCCCCCCTTAC
TATAAAAATAACGTCTACGTTTATATCCTAACAAGCCCAGAAAATGAGTTTCCTCTCATT
TTTGATAGGCCATCCTATGTATTTGATGTGTCAGAAAGAAGGCCCGCCAGAACCCGAGTG
GGACAGGTGCGAGCCACTGATAAAGACCTCCCCCAGAGCAGCCTCCTGTACTCCATCTCC
ACTGGAGGGGCCAGCCTCCAGTATCCAAATGTATTTTGGATTAATCCCAAGACAGGAGAA
CTCCAGCTGGTAACTAAAGTGGACTGTGAAACAACCCCCATCTATATTCTCAGAATCCAG
GCCACCAACAACGAAGACACAAGCTCTGTCACTGTTACTGTGAACATCCTTGAAGAAAAT
GATGAAAAGCCAATTTGTACTCCAAACTCTTATTTCCTGGCCCTCCCAGTGGATCTGAAA
GTTGGCACAAATATTCAGAATTTCAAGCTGACATGTACCGACCTTGATTCCAGCCCCAGA
TCTTTCCGTTATTCCATTGGCCCAGGTAACGTCAACAATCATTTCACCTTCTCTCCCAAT
GCTGGTTCCAATGTCACACGCCTGCTGCTTACATCTCGCTTTGACTATGCTGGTGGGTTT
GATAAGATCTGGGACTACAAGCTACTTGTCTACGTAACTGATGACAACTTGATGTCTGAC
AGGAAGAAAGCGGAGGCTCTTGTTGAGACAGGAACAGTGACACTGAGTATTAAAGTCATT
CCCCACCCAACCACTATCATCACCACGACCCCCAGGCCCAGGGTCACCTATCAGGTCCTG
AGGAAAAACGTTTACTCTCCATCTGCATGGTACGTGCCGTTTGTCATCACTTTGGGCTCC
ATATTGCTTCTGGGTCTCCTCGTGTACCTGGTCGTCCTATTGGCCAAAGCCATCCACAGA
CACTGCCCCTGCAAGACTGGGAAGAACAAGGAACCTCTGACAAAGAAAGGAGAAACGAAG
ACTGCAGAGAGAGACGTCGTGGTGGAAACTATCCAGATGAACACTATCTTTGATGGAGAA
GCCATAGATCCAGTGACCGGGGAAACATATGAATTCAACTCAAAAACTGGAGCCAGAAAG
TGGAAAGATCCACTAACCCAAATGCCAAAATGGAAAGAGTCCAGCCACCAGGGAGCTGCC
CCACGCAGAGTCACTGCTGGGGAAGGGATGGGGTCACTGAGAAGTGCCAACTGGGAAGAA
GATGAGCTGAGTGGCAAAGCGTGGGCTGAGGATGCTGGTCTGGGTTCCAGAAATGAGGGT
GGCAAGCTGGGCAACCCAAAGAACAGAAATCCAGCCTTCATGAACAGGGCTTACCCCAAA
CCACACCCAGGAAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 885 |
| Molecular Weight
| 97976.1 |
| Theoretical pI
| 5.06 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cadherin-related family member 3
MQEAIILLALLGAMSGGEALHLILLPATGNVAENSPPGTSVHKFSVKLSASLSPVIPGFP
QIVNSNPLTEAFRVNWLSGTYFEVVTTGMEQLDFETGPNIFDLQIYVKDEVGVTDLQVLT
VQVTDVNEPPQFQGNLAEGLHLYIVERANPGFIYQVEAFDPEDTSRNIPLSYFLISPPKS
FRMSANGTLFSTTELDFEAGHRSFHLIVEVRDSGGLKASTELQVNIVNLNDEVPRFTSPT
RVYTVLEELSPGTIVANITAEDPDDEGFPSHLLYSITTVSKYFMINQLTGTIQVAQRIDR
DAGELRQNPTISLEVLVKDRPYGGQENRIQITFIVEDVNDNPATCQKFTFSIMVPERTAK
GTLLLDLNKFCFDDDSEAPNNRFNFTMPSGVGSGSRFLQDPAGSGKIVLIGDLDYENPSN
LAAGNKYTVIIQVQDVAPPYYKNNVYVYILTSPENEFPLIFDRPSYVFDVSERRPARTRV
GQVRATDKDLPQSSLLYSISTGGASLQYPNVFWINPKTGELQLVTKVDCETTPIYILRIQ
ATNNEDTSSVTVTVNILEENDEKPICTPNSYFLALPVDLKVGTNIQNFKLTCTDLDSSPR
SFRYSIGPGNVNNHFTFSPNAGSNVTRLLLTSRFDYAGGFDKIWDYKLLVYVTDDNLMSD
RKKAEALVETGTVTLSIKVIPHPTTIITTTPRPRVTYQVLRKNVYSPSAWYVPFVITLGS
ILLLGLLVYLVVLLAKAIHRHCPCKTGKNKEPLTKKGETKTAERDVVVETIQMNTIFDGE
AIDPVTGETYEFNSKTGARKWKDPLTQMPKWKESSHQGAAPRRVTAGEGMGSLRSANWEE
DELSGKAWAEDAGLGSRNEGGKLGNPKNRNPAFMNRAYPKPHPGK
|
| External Links |
|---|
| GenBank ID Protein
| 40255133 |
| UniProtKB/Swiss-Prot ID
| Q6ZTQ4 |
| UniProtKB/Swiss-Prot Entry Name
| CDHR3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_152750.4 |
| GeneCard ID
| CDHR3 |
| GenAtlas ID
| CDHR3 |
| HGNC ID
| HGNC:26308 |
| References |
|---|
| General References
| Not Available |