| Identification |
|---|
| HMDB Protein ID
| CDBP02731 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cadherin-like protein 26 |
| Description
| Not Available |
| Synonyms
|
- Cadherin-like protein VR20
|
| Gene Name
| CDH26 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 20q13.33 |
| SNPs
| CDH26 |
| Gene Sequence
|
>2499 bp
ATGGCCATGAGATCCGGGAGGCACCCCTCGCTGCTGCTGCTTCTAGTGCTGCTGCTGTGG
CTGCTGCAGGTCAGTATCATTGACAGTGTTCAACAGGAAACAGATGATCTTACTAAGCAA
ACAAAGGAAAAGATCTACCAGCCTCTACGGCGATCCAAGAGAAGATGGGTTATCACCACC
TTGGAGCTGGAGGAGGAAGACCCGGGACCCTTTCCCAAACTCATTGGTGAGCTGTTCAAT
AATATGTCTTATAACATGTCACTAATGTATCTAATCAGTGGACCTGGTGTGGATGAATAT
CCAGAGATTGGTTTGTTTTCTCTAGAAGATCATGAGAACGGAAGGATATATGTTCACCGC
CCTGTCGATCGAGAAATGACACCATCTTTCACGGTTTATTTTGATGTTGTGGAGCGCTCA
ACAGGAAAAATTGTGGATACATCCTTGATTTTCAACATTAGGATCAGTGATGTGAATGAT
CATGCACCCCAGTTTCCAGAGAAGGAATTTAACATCACTGTGCAAGAAAACCAATCTGCA
GGGCAACCTATTTTTCAGATGTTAGCAGTCGATTTGGATGAAGAAAACACTCCAAATTCT
CAAGTCCTTTACTTCCTCATTTCTCAAACACCATTACTGAAAGAAAGTGGTTTCCGGGTT
GATCGCCTTAGTGGAGAAATACGACTCTCTGGCTGCTTAGATTATGAGACCGCTCCTCAG
TTTACACTGCTAATCAGAGCCAGGGACTGTGGAGAACCGTCACTGTCATCCACGACCACC
GTTCACGTGGATGTGCAAGAAGGCAACAACCACAGGCCTGCATTTACCCAGGAGAACTAT
AAGGTTCAGATTCCTGAAGGCCGAGCCAGCCAGGGCGTGTTGCGTCTCCTGGTTCAAGAT
CGAGATTCTCCATTTACATCAGCTTGGAGAGCAAAATTCAACATATTGCATGGCAATGAA
GAGGGGCATTTTGACATTTCGACTGACCCTGAGACCAACGAAGGGATATTAAATGTTATC
AAGCCTTTGGATTATGAGACTCGCCCAGCGCAAAGCCTCATCATTGTCGTGGAGAATGAG
GAGAGGCTCGTCTTCTGTGAGAGAGGAAAGCTTCAGCCGCCAAGGAAGGCAGCAGCCAGC
GCCACTGTGAGTGTGCAGGTGACAGACGCCAACGACCCACCAGCCTTTCACCCCCAGAGC
TTCATTGTCAATAAAGAGGAGGGCGCCAGGCCTGGGACCCTGTTGGGAACTTTTAATGCC
ATGGATCCAGACAGCCAGATAAGATATGAACTGGTTCATGACCCAGCAAATTGGGTCAGC
GTCGACAAAAACTCCGGAGTGGTCATCACCGTGGAGCCAATTGACCGAGAATCCCCTCAT
GTAAATAACAGTTTTTATGTAATCATCATTCACGCTGTTGATGATGGCTTCCCACCGCAG
ACTGCTACAGGGACCCTAATGCTCTTCCTGTCTGACATCAATGACAACGTCCCGACTCTC
CGGCCACGTTCCCGCTACATGGAGGTCTGTGAGTCTGCTGTGCATGAGCCCCTCCACATC
GAGGCAGAGGATCCGGACCTGGAGCCGTTCTCTGACCCATTTACATTTGAATTGGACAAT
ACCTGGGGAAATGCGGAGGACACATGGAAGTTGGGGAGAAATTGGGGTCAATCAGTTGAA
CTTTTAACCTTGAGAAGCCTGCCACGTGGTAATTACTTGGTGCCACTCTTCATTGGAGAC
AAACAGGGACTTTCCCAGAAGCAAACTGTCCATGTAAGGATCTGCCCCTGTGCCAGTGGG
CTCACATGTGTGGAGCTTGCAGATGCAGAAGTGGGGCTTCATGTGGGGGCCCTGTTCCCT
GTCTGTGCAGCATTTGTGGCTCTGGCAGTGGCTCTGCTTTTTCTGTTGCGATGCTATTTT
GTGCTTGAACCTAAGAGGCATGGATGCTCTGTATCCAATGATGAAGGCCACCAAACACTG
GTCATGTATAATGCGGAGAGCAAAGGCACTTCAGCCCAGACATGGTCAGATGTTGAAGGC
CAGAGGCCGGCTCTGCTCATCTGCACAGCTGCAGCAGGACCCACGCAGGGAGTTAAGGAT
CTCGAGGAAGTGCCTCCATCTGCAGCGAGTCAGTCAGCCCAAGCACGCTGTGCTCTGGGG
AGCTGGGGTTATGGCAAGCCCTTTGAGCCAAGAAGTGTGAAAAACATACACTCTACTCCT
GCTTACCCAGATGCCACAATGCACAGACAACTCCTGGCTCCGGTGGAAGGAAGGATGGCA
GAGACATTGAATCAGAAACTCCATGTTGCCAATGTGCTGGAAGATGACCCCGGCTACCTA
CCTCACGTCTACAGCGAGGAAGGGGAGTGTGGAGGGGCCCCATCCCTCAGCTCTCTGGCC
AGCTTGGAACAGGAGTTGCAACCTGATTTGCTGGACTCTTTGGGTTCAAAAGCGACTCCG
TTTGAGGAAATATATTCAGAGTCAGGTGTTCCTTCCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 852 |
| Molecular Weight
| 95277.1 |
| Theoretical pI
| 5.78 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cadherin-like protein 26
MAMRSGRHPSLLLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITT
LELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHR
PVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSA
GQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRVDRLSGEIRLSGCLDYETAPQ
FTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQD
RDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENE
ERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNA
MDPDSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQ
TATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDN
TWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASG
LTCVELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTL
VMYNAESKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKAYPDATMHRQLLAPVEGRMAE
TLNQSKERNRFSLSRGCIIPQGRATAGRGLPQDIYKEMMPRRLTQTGKRKHGALARTPSF
KKVVYDHKEDEENKAGRKQRSHLFKVMQLRNEQGGVRVQSAHSPSPLNKKACFPGDYRGE
SAGGHNCRAVSG
|
| External Links |
|---|
| GenBank ID Protein
| 29570800 |
| UniProtKB/Swiss-Prot ID
| Q8IXH8 |
| UniProtKB/Swiss-Prot Entry Name
| CAD26_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| CDH26 |
| GenAtlas ID
| CDH26 |
| HGNC ID
| HGNC:15902 |
| References |
|---|
| General References
| Not Available |