Identification
HMDB Protein ID CDBP02731
Secondary Accession Numbers Not Available
Name Cadherin-like protein 26
Description Not Available
Synonyms
  1. Cadherin-like protein VR20
Gene Name CDH26
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
homophilic cell adhesion
cell adhesion
cellular process
cell-cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 20q13.33
SNPs CDH26
Gene Sequence
>2499 bp
ATGGCCATGAGATCCGGGAGGCACCCCTCGCTGCTGCTGCTTCTAGTGCTGCTGCTGTGG
CTGCTGCAGGTCAGTATCATTGACAGTGTTCAACAGGAAACAGATGATCTTACTAAGCAA
ACAAAGGAAAAGATCTACCAGCCTCTACGGCGATCCAAGAGAAGATGGGTTATCACCACC
TTGGAGCTGGAGGAGGAAGACCCGGGACCCTTTCCCAAACTCATTGGTGAGCTGTTCAAT
AATATGTCTTATAACATGTCACTAATGTATCTAATCAGTGGACCTGGTGTGGATGAATAT
CCAGAGATTGGTTTGTTTTCTCTAGAAGATCATGAGAACGGAAGGATATATGTTCACCGC
CCTGTCGATCGAGAAATGACACCATCTTTCACGGTTTATTTTGATGTTGTGGAGCGCTCA
ACAGGAAAAATTGTGGATACATCCTTGATTTTCAACATTAGGATCAGTGATGTGAATGAT
CATGCACCCCAGTTTCCAGAGAAGGAATTTAACATCACTGTGCAAGAAAACCAATCTGCA
GGGCAACCTATTTTTCAGATGTTAGCAGTCGATTTGGATGAAGAAAACACTCCAAATTCT
CAAGTCCTTTACTTCCTCATTTCTCAAACACCATTACTGAAAGAAAGTGGTTTCCGGGTT
GATCGCCTTAGTGGAGAAATACGACTCTCTGGCTGCTTAGATTATGAGACCGCTCCTCAG
TTTACACTGCTAATCAGAGCCAGGGACTGTGGAGAACCGTCACTGTCATCCACGACCACC
GTTCACGTGGATGTGCAAGAAGGCAACAACCACAGGCCTGCATTTACCCAGGAGAACTAT
AAGGTTCAGATTCCTGAAGGCCGAGCCAGCCAGGGCGTGTTGCGTCTCCTGGTTCAAGAT
CGAGATTCTCCATTTACATCAGCTTGGAGAGCAAAATTCAACATATTGCATGGCAATGAA
GAGGGGCATTTTGACATTTCGACTGACCCTGAGACCAACGAAGGGATATTAAATGTTATC
AAGCCTTTGGATTATGAGACTCGCCCAGCGCAAAGCCTCATCATTGTCGTGGAGAATGAG
GAGAGGCTCGTCTTCTGTGAGAGAGGAAAGCTTCAGCCGCCAAGGAAGGCAGCAGCCAGC
GCCACTGTGAGTGTGCAGGTGACAGACGCCAACGACCCACCAGCCTTTCACCCCCAGAGC
TTCATTGTCAATAAAGAGGAGGGCGCCAGGCCTGGGACCCTGTTGGGAACTTTTAATGCC
ATGGATCCAGACAGCCAGATAAGATATGAACTGGTTCATGACCCAGCAAATTGGGTCAGC
GTCGACAAAAACTCCGGAGTGGTCATCACCGTGGAGCCAATTGACCGAGAATCCCCTCAT
GTAAATAACAGTTTTTATGTAATCATCATTCACGCTGTTGATGATGGCTTCCCACCGCAG
ACTGCTACAGGGACCCTAATGCTCTTCCTGTCTGACATCAATGACAACGTCCCGACTCTC
CGGCCACGTTCCCGCTACATGGAGGTCTGTGAGTCTGCTGTGCATGAGCCCCTCCACATC
GAGGCAGAGGATCCGGACCTGGAGCCGTTCTCTGACCCATTTACATTTGAATTGGACAAT
ACCTGGGGAAATGCGGAGGACACATGGAAGTTGGGGAGAAATTGGGGTCAATCAGTTGAA
CTTTTAACCTTGAGAAGCCTGCCACGTGGTAATTACTTGGTGCCACTCTTCATTGGAGAC
AAACAGGGACTTTCCCAGAAGCAAACTGTCCATGTAAGGATCTGCCCCTGTGCCAGTGGG
CTCACATGTGTGGAGCTTGCAGATGCAGAAGTGGGGCTTCATGTGGGGGCCCTGTTCCCT
GTCTGTGCAGCATTTGTGGCTCTGGCAGTGGCTCTGCTTTTTCTGTTGCGATGCTATTTT
GTGCTTGAACCTAAGAGGCATGGATGCTCTGTATCCAATGATGAAGGCCACCAAACACTG
GTCATGTATAATGCGGAGAGCAAAGGCACTTCAGCCCAGACATGGTCAGATGTTGAAGGC
CAGAGGCCGGCTCTGCTCATCTGCACAGCTGCAGCAGGACCCACGCAGGGAGTTAAGGAT
CTCGAGGAAGTGCCTCCATCTGCAGCGAGTCAGTCAGCCCAAGCACGCTGTGCTCTGGGG
AGCTGGGGTTATGGCAAGCCCTTTGAGCCAAGAAGTGTGAAAAACATACACTCTACTCCT
GCTTACCCAGATGCCACAATGCACAGACAACTCCTGGCTCCGGTGGAAGGAAGGATGGCA
GAGACATTGAATCAGAAACTCCATGTTGCCAATGTGCTGGAAGATGACCCCGGCTACCTA
CCTCACGTCTACAGCGAGGAAGGGGAGTGTGGAGGGGCCCCATCCCTCAGCTCTCTGGCC
AGCTTGGAACAGGAGTTGCAACCTGATTTGCTGGACTCTTTGGGTTCAAAAGCGACTCCG
TTTGAGGAAATATATTCAGAGTCAGGTGTTCCTTCCTAA
Protein Properties
Number of Residues 852
Molecular Weight 95277.1
Theoretical pI 5.78
Pfam Domain Function
Signals
  • ["1-26"]
Transmembrane Regions
  • ["615-635"]
Protein Sequence
>Cadherin-like protein 26
MAMRSGRHPSLLLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITT
LELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHR
PVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSA
GQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRVDRLSGEIRLSGCLDYETAPQ
FTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQD
RDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENE
ERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNA
MDPDSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQ
TATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDN
TWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASG
LTCVELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTL
VMYNAESKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKAYPDATMHRQLLAPVEGRMAE
TLNQSKERNRFSLSRGCIIPQGRATAGRGLPQDIYKEMMPRRLTQTGKRKHGALARTPSF
KKVVYDHKEDEENKAGRKQRSHLFKVMQLRNEQGGVRVQSAHSPSPLNKKACFPGDYRGE
SAGGHNCRAVSG
GenBank ID Protein 29570800
UniProtKB/Swiss-Prot ID Q8IXH8
UniProtKB/Swiss-Prot Entry Name CAD26_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID CDH26
GenAtlas ID CDH26
HGNC ID HGNC:15902
References
General References Not Available