| Identification |
|---|
| HMDB Protein ID
| CDBP02730 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cadherin-24 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| CDH24 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-24 mediate strong cell-cell adhesion |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q11.2 |
| SNPs
| CDH24 |
| Gene Sequence
|
>2460 bp
ATGTGGGGCCTGGTGAGGCTCCTGCTGGCCTGGCTGGGTGGCTGGGGCTGCATGGGGCGT
CTGGCAGCCCCAGCCCGGGCCTGGGCAGGGTCCCGGGAACACCCAGGGCCTGCTCTGCTG
CGGACTCGAAGGAGCTGGGTCTGGAACCAGTTCTTTGTCATTGAGGAATATGCTGGTCCA
GAGCCTGTTCTCATTGGCAAGCTGCACTCGGATGTTGACCGGGGAGAGGGCCGCACCAAG
TACCTGTTGACCGGGGAGGGGGCAGGCACCGTATTTGTGATTGATGAGGCCACAGGCAAT
ATTCATGTTACCAAGAGCCTTGACCGGGAGGAAAAGGCGCAATATGTGCTACTGGCCCAA
GCCGTGGACCGAGCCTCCAACCGGCCCCTGGAGCCCCCATCAGAGTTCATCATCAAAGTG
CAAGACATCAACGACAATCCACCCATTTTTCCCCTTGGGCCCTACCATGCCACCGTGCCC
GAGATGTCCAATGTCGGGACATCAGTGATCCAGGTGACTGCTCACGATGCTGATGACCCC
AGCTATGGGAACAGTGCCAAGCTGGTGTACACTGTTCTGGATGGACTGCCTTTCTTCTCT
GTGGACCCCCAGACTGGAGTGGTGCGTACAGCCATCCCCAACATGGACCGGGAGACACAG
GAGGAGTTCTTGGTGGTGATCCAGGCCAAGGACATGGGCGGCCACATGGGGGGGCTGTCA
GGCAGCACTACGGTGACTGTCACGCTCAGCGATGTCAACGACAACCCCCCCAAGTTCCCA
CAGAGCCTATACCAGTTCTCCGTGGTGGAGACAGCTGGACCTGGCACACTGGTGGGCCGG
CTCCGGGCCCAGGACCCAGACCTGGGGGACAACGCCCTGATGGCATACAGCATCCTGGAT
GGGGAGGGGTCTGAGGCCTTCAGCATCAGCACAGACTTGCAGGGTCGAGACGGGCTCCTC
ACTGTCCGCAAGCCCCTAGACTTTGAGAGCCAGCGCTCCTACTCCTTCCGTGTCGAGGCC
ACCAACACGCTCATTGACCCAGCCTATCTGCGGCGAGGGCCCTTCAAGGATGTGGCCTCT
GTGCGTGTGGCAGTGCAAGATGCCCCAGAGCCACCTGCCTTCACCCAGGCTGCCTACCAC
CTGACAGTGCCTGAGAACAAGGCCCCGGGGACCCTGGTAGGCCAGATCTCCGCGGCTGAC
CTGGACTCCCCTGCCAGCCCAATCAGATACTCCATCCTCCCCCACTCAGATCCGGAGCGT
TGCTTCTCTATCCAGCCCGAGGAAGGCACCATCCATACAGCAGCACCCCTGGATCGCGAG
GCTCGCGCCTGGCACAACCTCACTGTGCTGGCTACAGAGCTCGGCTGGAGCTGGGGGCCA
GAAAGGGGCTGGGTACCTCTTCTGGTTGCTGAGTGGAGTGCACCAGCAGCCCCACCCCAG
AGAAGCCCTGTTGGAAGCGCTGTGGGAATCCCCCAAGACAGTTCTGCACAGGCCTCGCGC
GTGCAAGTGGCCATCCAGACCCTGGATGAGAATGACAATGCTCCCCAGCTGGCTGAGCCC
TACGATACTTTTGTGTGTGACTCTGCAGCTCCTGGCCAGCTGATTCAGGTCATCCGGGCC
CTGGACAGAGATGAAGTTGGCAACAGTAGCCATGTCTCCTTTCAAGGTCCTCTGGGCCCT
GATGCCAACTTTACTGTCCAGGACAACCGAGATGGCTCCGCCAGCCTGCTGCTGCCCTCC
CGCCCTGCTCCACCCCGCCATGCCCCCTACTTGGTTCCCATAGAACTGTGGGACTGGGGG
CAGCCGGCGCTGAGCAGCACTGCCACAGTGACTGTTAGTGTGTGCCGCTGCCAGCCTGAC
GGCTCTGTGGCATCCTGCTGGCCTGAGGCTCACCTCTCAGCTGCTGGGCTCAGCACCGGC
GCCCTGCTTGCCATCATCACCTGTGTGGGTGCCCTGCTTGCCCTGGTGGTGCTCTTCGTG
GCCCTGCGGCGGCAGAAGCAAGAAGCACTGATGGTACTGGAGGAGGAGGACGTCCGAGAG
AACATCATCACCTACGACGACGAGGGCGGCGGCGAGGAGGACACCGAGGCCTTCGACATC
ACGGCCTTGCAGAACCCGGACGGGGCGGCCCCCCCGGCGCCCGGCCCTCCCGCGCGCCGA
GACGTGTTGCCCCGGGCCCGGGTGTCGCGCCAGCCCAGACCCCCCGGCCCCGCCGACGTG
GCGCAGCTCCTGGCGCTGCGGCTCCGCGAGGCGGACGAGGACCCCGGCGTACCCCCGTAC
GACTCGGTGCAGGTGTACGGCTACGAGGGCCGCGGCTCCTCTTGCGGCTCCCTCAGCTCC
CTGGGCTCCGGCAGCGAAGCCGGCGGCGCCCCCGGCCCCGCGGAGCCGCTGGACGACTGG
GGTCCGCTCTTCCGCACCCTGGCCGAGCTGTATGGGGCCAAGGAGCCCCCGGCCCCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 819 |
| Molecular Weight
| 87751.5 |
| Theoretical pI
| 4.4 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cadherin-24
MWGLVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGP
EPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQ
AVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDP
SYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLS
GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD
GEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVAS
VRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPER
CFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQ
RSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRA
LDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWG
QPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV
ALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARR
DVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSS
LGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKEPPAP
|
| External Links |
|---|
| GenBank ID Protein
| 32880206 |
| UniProtKB/Swiss-Prot ID
| Q86UP0 |
| UniProtKB/Swiss-Prot Entry Name
| CAD24_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_022478.3 |
| GeneCard ID
| CDH24 |
| GenAtlas ID
| CDH24 |
| HGNC ID
| HGNC:14265 |
| References |
|---|
| General References
| Not Available |