Identification
HMDB Protein ID CDBP02727
Secondary Accession Numbers Not Available
Name Cadherin-20
Description Not Available
Synonyms Not Available
Gene Name CDH20
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types
GO Classification
Component
membrane
cell part
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cell adhesion
cellular process
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 18q21.33
SNPs CDH20
Gene Sequence
>2406 bp
ATGTGGACTTCTGGTAGAATGAGCAATGCAAAGAACTGGCTTGGACTTGGCATGTCCTTG
TACTTCTGGGGGCTGATGGACCTTACGACCACCGTTCTCTCGGACACCCCAACACCACAA
GGTGAATTAGAAGCACTCCTGTCAGACAAGCCACAGTCACATCAGCGGACCAAGAGGAGC
TGGGTTTGGAACCAGTTTTTCGTTCTGGAAGAGTACACTGGGACCGACCCTTTGTATGTC
GGCAAGCTTCATTCAGATATGGACAGGGGAGACGGATCCATCAAATACATCCTCTCGGGA
GAAGGTGCTGGCATCGTGTTTACCATCGACGACACCACTGGAGACATCCACGCCATTCAG
AGGCTCGACCGAGAGGAAAGAGCCCAGTATACTCTAAGGGCTCAAGCCCTAGACAGGCGG
ACGGGCAGGCCAATGGAGCCCGAGTCAGAGTTCATCATCAAAATTCAAGACATCAATGAC
AATGAGCCCAAGTTCCTGGACGGACCTTATGTGGCCACTGTGCCAGAAATGTCCCCTGTG
GGTACCTCCGTCATCCAAGTGACAGCCACAGATGCAGATGACCCGACCTACGGCAACAGT
GCCAGGGTGGTGTACAGCATTCTTCAGGGCCAGCCATATTTTTCTGTGGACTCTAAAACA
GGTGTAATTAGGACAGCGCTCATGAACATGGACAGAGAAGCCAAAGAATACTACGAAGTG
ATTATCCAAGCCAAGGACATGGGAGGGCAGCTTGGAGGATTAGCTGGGACCACAACAGTC
AACATCACCCTCTCAGATGTCAATGATAACCCACCCCGCTTTCCCCAGAAACATTACCAG
ATGAGTGTGTTGGAATCAGCTCCAATTAGCTCCACTGTCGGGAGAGTGTTTGCCAAGGAC
TTGGATGAAGGCATCAATGCAGAGATGAAATATACTATTGTGGATGGAGATGGTGCAGAT
GCCTTTGACATTAGCACAGATCCCAATTTCCAAGTTGGTATCATAACTGTGAAGAAGCCC
CTGAGTTTTGAAAGCAAGAAAAGCTACACCTTAAAGGTGGAGGGAGCCAATCCTCACCTA
GAGATGCGTTTTCTGAACTTGGGCCCATTTCAGGACACAACAACAGTGCACATCAGTGTG
GAAGACGTGGACGAGCCCCCTGTGTTTGAACCTGGCTTTTACTTTGTGGAGGTGCCTGAG
GATGTGGCGATTGGAACAACCATACAGATCATTTCTGCCAAGGACCCAGATGTGACCAAC
AACTCAATCAGATACTCCATTGATAGAAGCAGTGACCCTGGAAGATTTTTCTATGTTGAC
ATTACAACAGGTGCCCTAATGACAGCAAGACCCCTAGACCGGGAAGAATTTTCTTGGCAT
AATATCACTGTCCTTGCTATGGAAATGAACAATCCCTCCCAGGTTGGAAGTGTTCCTGTC
ACAATCAAAGTCTTAGATGTGAATGACAATGCTCCAGAGTTCCCCAGATTCTATGAAGCT
TTTGTCTGTGAGAACGCCAAGGCAGGACAGCTGATCCAGACAGTGAGTGCGGTGGACCAA
GATGACCCACGCAATGGTCAGCATTTCTACTACAGCTTGGCTCCTGAGGCTGCTAACAAC
CCCAACTTTACCATAAGGGACAACCAAGATAACACAGCACGGATTCTAACCAGGAGGTCT
GGTTTCCGGCAGCAGGAGCAGAGTGTCTTTCACCTGCCTATCCTGATAGCAGATAGCGGG
CAGCCCGTGCTGAGCAGCACAGGCACACTGACCATCCAAGTGTGCAGCTGTGATGACGAC
GGCCACGTCATGTCCTGCAGCCCAGAGGCCTACATGCTCCCAGTCAGTTTGAGCCGGGGC
CCCCTCATTGCCATCCTCGCCTGCATCTTTGTCCTCCTAGTGCTGGTGTTGCTCATTTTG
TCCATGAGGCGGCACCGGAAACAACCATACATCATCGACGACGAGGAAAACATCCACGAG
AACATCGTCCGCTACGACGACGAGGGCGGCGGCGAGGAGGACACCGAGGCCTTCGACATC
GCGGCCATGTGGAACCCCCGGGAGGCGCAGGCGGGGGCCGGCCCCAAGACGCGGCAGGAC
ATGCTGCCCGAGATCGAGAGCCTCTTCCGCTACGTGCCTCAGACGTGCGCAGTGAACAGC
ACTGTCCACAGCTACGTGCTGGCCAAGCTCTACGAGGCCGACATGGACCTGTGGACACCG
CCCTTCGACTCCCTCCAGACGTATATGTTCGAGGGGGACGGCCCTGTGGCGGGGTCGCTG
AGCTCCCTGCAGTCGGCCACGTCGGACTCGGAACAGAGCTTCGACTTCCTGACGGACTGG
GGGCCCCGCTTCCGGAAGCTGGCCGAGCTCTACGGGGCGTCGGAGGGACCCGCGCCGCTG
TGGTGA
Protein Properties
Number of Residues 801
Molecular Weight 88992.0
Theoretical pI 4.3
Pfam Domain Function
Signals
  • ["1-34"]
Transmembrane Regions
  • ["620-640"]
Protein Sequence
>Cadherin-20
MWTSGRMSNAKNWLGLGMSLYFWGLMDLTTTVLSDTPTPQGELEALLSDKPQSHQRTKRS
WVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQ
RLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPV
GTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEV
IIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKD
LDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHL
EMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTN
NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPV
TIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANN
PNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD
GHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHE
NIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNS
TVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDW
GPRFRKLAELYGASEGPAPLW
GenBank ID Protein 10834607
UniProtKB/Swiss-Prot ID Q9HBT6
UniProtKB/Swiss-Prot Entry Name CAD20_HUMAN
PDB IDs Not Available
GenBank Gene ID AF217289
GeneCard ID CDH20
GenAtlas ID CDH20
HGNC ID HGNC:1760
References
General References Not Available