| Identification |
|---|
| HMDB Protein ID
| CDBP02719 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cadherin-10 |
| Description
| Not Available |
| Synonyms
|
- T2-cadherin
|
| Gene Name
| CDH10 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5p14.2 |
| SNPs
| CDH10 |
| Gene Sequence
|
>2367 bp
ATGACAATACATCAATTTTTGCTACTGTTTCTATTCTGGGTATGCCTGCCACATTTCTGC
TCTCCAGAAATAATGTTCAGAAGGACGCCTGTGCCACAGCAAAGAATTTTAAGTTCACGT
GTACCAAGGAGTGATGGCAAAATTCTCCATCGTCAAAAACGTGGTTGGATGTGGAATCAA
TTTTTCTTACTTGAAGAATATACAGGATCTGATTATCAGTACGTAGGCAAGCTACATTCA
GACCAAGATAAAGGAGATGGATCACTCAAATATATCTTATCTGGAGATGGAGCTGGTACT
CTTTTTATTATTGATGAAAAAACAGGTGATATTCATGCCACAAGGCGAATTGATAGGGAG
GAAAAGGCCTTTTATACTCTACGCGCACAAGCTATTAACAGAAGAACTCTGAGGCCAGTA
GAGCCAGAGTCAGAGTTTGTGATCAAAATTCATGATATCAATGACAATGAGCCAACGTTC
CCAGAAGAAATCTATACAGCTAGTGTTCCCGAAATGTCTGTTGTAGGTACTTCTGTGGTG
CAAGTCACAGCTACAGATGCCGATGACCCTTCATATGGGAACAGCGCCAGAGTCATTTAC
AGCATACTTCAAGGGCAGCCCTATTTCTCTGTGGAGCCTGAAACAGGTATCATCAGGACT
GCTTTACCGAACATGAACAGAGAAAACAGAGAGCAATACCAAGTGGTCATCCAGGCCAAA
GACATGGGCGGCCAGATGGGAGGCTTATCGGGGACAACCACTGTGAACATCACGCTGACA
GATGTCAATGACAACCCACCACGTTTCCCCCAGAACACTATTCATCTTCGAGTTCTTGAA
TCCTCCCCAGTTGGCACAGCCATTGGAAGTGTCAAAGCAACTGATGCTGACACTGGGAAA
AATGCTGAAGTAGAATACCGAATTATTGATGGTGACGGTACTGATATGTTTGACATCGTG
ACTGAGAAGGACACACAGGAAGGCATCATCACTGTGAAAAAGCCACTCGACTATGAGAGC
CGAAGACTTTATACTCTGAAAGTCGAAGCAGAAAACACCCATGTAGATCCCCGTTTTTAT
TACCTAGGACCATTTAAAGATACTACCATAGTGAAAATCTCTATAGAAGATGTGGATGAA
CCTCCTGTTTTTAGTAGGTCCTCCTATCTGTTTGAAGTTCATGAAGATATTGAAGTGGGC
ACAATCATTGGTACTGTAATGGCAAGGGACCCAGATTCTATTTCCAGCCCCATTAGATTT
TCCTTGGATCGCCATACTGACCTTGACAGAATCTTTAACATTCATTCAGGAAATGGATCT
CTTTATACATCAAAACCTCTTGACCGTGAACTATCTCAGTGGCATAATCTTACTGTTATT
GCTGCTGAAATCAACAATCCCAAAGAGACAACACGCGTGGCTGTTTTTGTGAGAATTTTG
GATGTTAATGACAATGCCCCACAGTTTGCTGTGTTCTATGACACTTTTGTATGTGAAAAT
GCCAGACCAGGGCAGCTAATACAGACTATAAGTGCAGTAGACAAAGATGACCCTTTAGGT
GGACAGAAATTTTTTTTCAGTTTAGCTGCTGTCAATCCAAACTTCACAGTACAGGATAAT
GAAGATAATACTGCCAGAATCTTAACCAGAAAAAATGGATTCAATAGACATGAAATCAGT
ACCTATCTCTTGCCTGTGGTGATATCAGACAATGATTACCCAATTCAGAGCAGCACAGGC
ACACTGACCATTCGAGTGTGTGCTTGTGACAGCCAAGGCAACATGCAATCCTGCAGTGCT
GAAGCCCTGCTCCTCCCTGCCGGCCTCAGCACTGGGGCCTTGATCGCCATCCTCCTCTGC
ATCATCATTCTACTGGTTATAGTAGTACTGTTTGCAGCTCTGAAAAGACAGCGAAAAAAA
GAGCCTCTGATCTTGTCAAAAGAAGATATCAGAGACAACATTGTGAGCTATAACGATGAG
GGTGGTGGAGAGGAGGACACCCAGGCCTTTGATATCGGCACCCTGAGGAATCCTGCAGCC
ATTGAGGAAAAAAAGCTCCGGCGAGATATTATTCCAGAAACGTTATTTATTCCTCGGAGG
ACTCCTACAGCTCCAGATAACACGGACGTCCGGGATTTCATTAATGAAAGGCTAAAAGAG
CATGATCTTGACCCCACCGCACCCCCCTACGACTCACTTGCAACCTATGCCTATGAAGGA
AATGATTCCATTGCTGAATCTCTGAGTTCATTAGAATCAGGTACTACTGAAGGAGACCAA
AACTACGATTACCTCCGAGAATGGGGCCCTCGGTTTAATAAGCTAGCAGAAATGTATGGT
GGTGGGGAAAGTGACAAAGACTCTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 788 |
| Molecular Weight
| 88450.4 |
| Theoretical pI
| 4.59 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cadherin-10
MTIHQFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVPRSDGKILHRQKRGWMWNQ
FFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDRE
EKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVV
QVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAK
DMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGK
NAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFY
YLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRF
SLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRIL
DVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDN
EDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSA
EALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDE
GGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKE
HDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYG
GGESDKDS
|
| External Links |
|---|
| GenBank ID Protein
| 6483303 |
| UniProtKB/Swiss-Prot ID
| Q9Y6N8 |
| UniProtKB/Swiss-Prot Entry Name
| CAD10_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB035303 |
| GeneCard ID
| CDH10 |
| GenAtlas ID
| CDH10 |
| HGNC ID
| HGNC:1749 |
| References |
|---|
| General References
| Not Available |