Identification |
HMDB Protein ID
| CDBP02705 |
Secondary Accession Numbers
| Not Available |
Name
| Calcium-binding tyrosine phosphorylation-regulated protein |
Description
| Not Available |
Synonyms
|
- CT88
- Calcium-binding protein 86
- Cancer/testis antigen 88
- FSP-2
- Fibrousheathin II
- Fibrousheathin-2
- Testis-specific calcium-binding protein CBP86
|
Gene Name
| CABYR |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in cAMP-dependent protein kinase regulator activity |
Specific Function
| May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium |
GO Classification
|
Function |
enzyme regulator activity |
kinase regulator activity |
protein kinase regulator activity |
camp-dependent protein kinase regulator activity |
Process |
biological regulation |
regulation of biological process |
regulation of cellular process |
signal transduction |
|
Cellular Location
|
- Cytoplasm
- Cell projection
- cilium
- Isoform 5:Nucleus
- flagellum
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 18q11.2 |
SNPs
| CABYR |
Gene Sequence
|
>1482 bp
ATGATTTCTTCAAAGCCCAGACTTGTCGTACCCTATGGCCTCAAGACTCTGCTCGAGGGA
ATTAGCAGAGCTGTTCTCAAAACCAACCCATCAAACATCAACCAGTTTGCAGCAGCTTAT
TTTCAAGAACTTACTATGTATAGAGGGAATACTACTATGGATATAAAAGATCTGGTTAAA
CAATTTCATCAGATTAAAGTAGAGAAATGGTCAGAAGGAACGACACCACAGAAGAAATTA
GAATGTTTAAAAGAACCAGGAAAAACATCTGTAGAATCTAAAGTACCTACCCAGATGGAA
AAATCTACAGACACAGACGAGGACAATGTAACCAGAACAGAATATAGTGACAAAACCACC
CAGTTTCCATCAGTTTATGCTGTGCCAGGCACTGAGCAAACGGAAGCAGTTGGTGGTCTT
TCTTCCAAACCAGCCACCCCTAAGACTACTACCCCACCCTCATCACCACCTCCAACAGCT
GTCTCACCAGAGTTTGCCTACGTCCCAGCTGACCCAGCTCAGCTTGCTGCTCAGATGTTA
GGTAAAGTTTCATCTATTCATTCTGATCAATCTGATGTGTTAATGGTGGATGTGGCAACC
AGTATGCCTGTTGTTATCAAGGAGGTGCCAAGCTCAGAGGCTGCTGAAGATGTCATGGTG
GCTGCTCCTCTTGTGTGTTCTGGAAAGGTGCTAGAAGTGCAGGTTGTGAACCAAACATCT
GTCCATGTAGATTTGGGTTCTCAACCTAAAGAAAATGAGGCTGAACCATCAACGGCTTCC
TCAGTCCCCTTGCAGGATGAACAAGAACCTCCTGCTTATGATCAAGCTCCTGAGGTCACT
TTGCAGGCTGATATTGAGGTTATGTCAACTGTTCATATATCATCTGTCTATAACGATGTG
CCTGTGACTGAAGGAGTTGTTTATATCGAGCAACTGCCAGAACAAATAGTTATCCCTTTT
ACTGATCAAGTTGCTTGTCTTAAAGAAAATGAGCAGTCAAAAGAAAATGAGCAGTCACCA
CGAGTTAGTCCCAAATCTGTAGTAGAAAAGACCACCTCTGGCATGTCTAAAAAATCTGTA
GAGTCCGTAAAACTTGCACAGTTGGAGGAGAATGCAAAATATTCCTCAGTATATATGGAG
GCAGAAGCAACAGCTCTGCTCTCTGACACATCTTTGAAAGGTCAGCCTGAGGTACCTGCA
CAACTCCTGGATGCAGAAGGTGCTATCAAAATAGGCTCTGAAAAATCTCTGCACCTTGAA
GTGGAGGTCACTTCAATAGTCTCTGACAATACTGGGCAGGAGGAGTCTGGGGAAAACTCT
GTACCCCAGGAGATGGAAGGCAGACCTGTGCTCTCTGGGGAAGCTGCAGAAGCAGTGCAC
TCAGGTACATCTGTAAAGTCATCTAGTGGCCCCTTCCCTCCTGCTCCAGAAGGCCTTACT
GCACCAGAAATTGAACCAGAAGGGGAATCAACAGCTGAATAA
|
Protein Properties |
Number of Residues
| 493 |
Molecular Weight
| 52773.6 |
Theoretical pI
| 4.2 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Calcium-binding tyrosine phosphorylation-regulated protein
MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRGNTTMDIKDLVK
QFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT
QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML
GKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTS
VHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDV
PVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSV
ESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLE
VEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLT
APEIEPEGESTAE
|
External Links |
GenBank ID Protein
| 3599530 |
UniProtKB/Swiss-Prot ID
| O75952 |
UniProtKB/Swiss-Prot Entry Name
| CABYR_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF088868 |
GeneCard ID
| CABYR |
GenAtlas ID
| CABYR |
HGNC ID
| HGNC:15569 |
References |
General References
| Not Available |