Identification
HMDB Protein ID CDBP02705
Secondary Accession Numbers Not Available
Name Calcium-binding tyrosine phosphorylation-regulated protein
Description Not Available
Synonyms
  1. CT88
  2. Calcium-binding protein 86
  3. Cancer/testis antigen 88
  4. FSP-2
  5. Fibrousheathin II
  6. Fibrousheathin-2
  7. Testis-specific calcium-binding protein CBP86
Gene Name CABYR
Protein Type Enzyme
Biological Properties
General Function Involved in cAMP-dependent protein kinase regulator activity
Specific Function May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium
GO Classification
Function
enzyme regulator activity
kinase regulator activity
protein kinase regulator activity
camp-dependent protein kinase regulator activity
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
Cellular Location
  1. Cytoplasm
  2. Cell projection
  3. cilium
  4. Isoform 5:Nucleus
  5. flagellum
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 18q11.2
SNPs CABYR
Gene Sequence
>1482 bp
ATGATTTCTTCAAAGCCCAGACTTGTCGTACCCTATGGCCTCAAGACTCTGCTCGAGGGA
ATTAGCAGAGCTGTTCTCAAAACCAACCCATCAAACATCAACCAGTTTGCAGCAGCTTAT
TTTCAAGAACTTACTATGTATAGAGGGAATACTACTATGGATATAAAAGATCTGGTTAAA
CAATTTCATCAGATTAAAGTAGAGAAATGGTCAGAAGGAACGACACCACAGAAGAAATTA
GAATGTTTAAAAGAACCAGGAAAAACATCTGTAGAATCTAAAGTACCTACCCAGATGGAA
AAATCTACAGACACAGACGAGGACAATGTAACCAGAACAGAATATAGTGACAAAACCACC
CAGTTTCCATCAGTTTATGCTGTGCCAGGCACTGAGCAAACGGAAGCAGTTGGTGGTCTT
TCTTCCAAACCAGCCACCCCTAAGACTACTACCCCACCCTCATCACCACCTCCAACAGCT
GTCTCACCAGAGTTTGCCTACGTCCCAGCTGACCCAGCTCAGCTTGCTGCTCAGATGTTA
GGTAAAGTTTCATCTATTCATTCTGATCAATCTGATGTGTTAATGGTGGATGTGGCAACC
AGTATGCCTGTTGTTATCAAGGAGGTGCCAAGCTCAGAGGCTGCTGAAGATGTCATGGTG
GCTGCTCCTCTTGTGTGTTCTGGAAAGGTGCTAGAAGTGCAGGTTGTGAACCAAACATCT
GTCCATGTAGATTTGGGTTCTCAACCTAAAGAAAATGAGGCTGAACCATCAACGGCTTCC
TCAGTCCCCTTGCAGGATGAACAAGAACCTCCTGCTTATGATCAAGCTCCTGAGGTCACT
TTGCAGGCTGATATTGAGGTTATGTCAACTGTTCATATATCATCTGTCTATAACGATGTG
CCTGTGACTGAAGGAGTTGTTTATATCGAGCAACTGCCAGAACAAATAGTTATCCCTTTT
ACTGATCAAGTTGCTTGTCTTAAAGAAAATGAGCAGTCAAAAGAAAATGAGCAGTCACCA
CGAGTTAGTCCCAAATCTGTAGTAGAAAAGACCACCTCTGGCATGTCTAAAAAATCTGTA
GAGTCCGTAAAACTTGCACAGTTGGAGGAGAATGCAAAATATTCCTCAGTATATATGGAG
GCAGAAGCAACAGCTCTGCTCTCTGACACATCTTTGAAAGGTCAGCCTGAGGTACCTGCA
CAACTCCTGGATGCAGAAGGTGCTATCAAAATAGGCTCTGAAAAATCTCTGCACCTTGAA
GTGGAGGTCACTTCAATAGTCTCTGACAATACTGGGCAGGAGGAGTCTGGGGAAAACTCT
GTACCCCAGGAGATGGAAGGCAGACCTGTGCTCTCTGGGGAAGCTGCAGAAGCAGTGCAC
TCAGGTACATCTGTAAAGTCATCTAGTGGCCCCTTCCCTCCTGCTCCAGAAGGCCTTACT
GCACCAGAAATTGAACCAGAAGGGGAATCAACAGCTGAATAA
Protein Properties
Number of Residues 493
Molecular Weight 52773.6
Theoretical pI 4.2
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Calcium-binding tyrosine phosphorylation-regulated protein
MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRGNTTMDIKDLVK
QFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT
QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML
GKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTS
VHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDV
PVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSV
ESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLE
VEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLT
APEIEPEGESTAE
GenBank ID Protein 3599530
UniProtKB/Swiss-Prot ID O75952
UniProtKB/Swiss-Prot Entry Name CABYR_HUMAN
PDB IDs Not Available
GenBank Gene ID AF088868
GeneCard ID CABYR
GenAtlas ID CABYR
HGNC ID HGNC:15569
References
General References Not Available