| Identification |
|---|
| HMDB Protein ID
| CDBP02681 |
| Secondary Accession Numbers
| Not Available |
| Name
| Putative annexin A2-like protein |
| Description
| Not Available |
| Synonyms
|
- Annexin A2 pseudogene 2
- Lipocortin II pseudogene
|
| Gene Name
| ANXA2P2 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response |
| GO Classification
|
| Function |
| calcium ion binding |
| lipid binding |
| phospholipid binding |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| enzyme regulator activity |
| enzyme inhibitor activity |
| lipase inhibitor activity |
| phospholipase inhibitor activity |
| calcium-dependent phospholipid binding |
| protein binding |
| cytoskeletal protein binding |
|
| Cellular Location
|
- Melanosome
- Secreted
- extracellular space
- extracellular matrix
- basement membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9p13 |
| SNPs
| ANXA2P2 |
| Gene Sequence
|
>1074 bp
ATGGGCCGCCAGCTAGCGGGGTGTGGAGACGCTGGGAAGAAGGCTTCCTTCAAAATGTCT
ACTGTTCACGAAATCCTGTGCAAGCTCAGCTTGGAGGGTGATCACTCTACACCCCCAAGT
GCATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCGGGATGCTTTGAACATT
GAAACAGCCATCAAGACCAAAGGTGTGGATGAGGTCACCATTGTCAACATTTTGACCAAC
CGCAGCAATGCACAGAGACAGGATATTGCCTTCGCCTACCAGAGAAGGACCAAAAAGGAA
CTTGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGACGGTGATTTTGGGCCTA
TTGAAGACACCTGCTCAGTATGACGCTTCTGAGCTAAAAGCTTCCATGAAGGGGCTGGGA
ACCGACGAGGACTCTCTCATTGAGATCATCTGCTCCAGAACCAACCAGGAGCTGCAGGAA
ATTAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAAGGACATTATTTCGGAC
ACATCTGGTGACTTCCGCAAGCTGATGGTTGCCCTGGCAAAGGGTAGAAGAGCAGAGGAT
GGCTCTGTCATTGATTATGAACTGATTGACCAAGATGCTCGGGATCTCTATGACGCTGGA
GTGAAGAGGAAAGGAACTGATGTTCCCAAGTGGATCAGCATCATGACCGAGCGGAGCGTG
CCCCACCTCCAGAAAGTATTTGATAGGTACAAGAGTTACAGCCCTTATGACATGTTGGAA
AGCATCAGGAAAGAGGTTAAAGGAGACCTGGAAAATGCTTTCCTGAACCTGGTTCAGTGC
ATTCAGAACAAGCCCCTGTATTTTGCTGATCGGCTGTATGACTCCATGAAGGGCAAGGGG
ACGCGAGATAAGGTCCTGATCAGAATCATGGTCTCCCGCAGTGAAGTGGACATGTTGAAA
ATTAGGTCTGAATTCAAGAGAAAGTACGGCAAGTCCCTGTACTATTATATCCAGCAAGAC
ACTAAGGGCGACTACCAGAAAGCGCTGCTGTACCTGTGTGGTGGAGATGACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 339 |
| Molecular Weight
| 38658.6 |
| Theoretical pI
| 6.94 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Putative annexin A2-like protein
MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNIV
TNRDNAQRQDIVFSYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKG
LGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRA
EDGSVIDYELIDQDAQDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDM
LESIRKEVKGDLENAFLNLVQRIQNKPLYFADQLYDSMKGKGTRDKVLIRIMVSRSEVDM
LKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD
|
| External Links |
|---|
| GenBank ID Protein
| 50845388 |
| UniProtKB/Swiss-Prot ID
| A6NMY6 |
| UniProtKB/Swiss-Prot Entry Name
| AXA2L_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| NM_001002858 |
| GeneCard ID
| ANXA2P2 |
| GenAtlas ID
| ANXA2P2 |
| HGNC ID
| HGNC:539 |
| References |
|---|
| General References
| Not Available |