| Identification |
|---|
| HMDB Protein ID
| CDBP02664 |
| Secondary Accession Numbers
| Not Available |
| Name
| Anthrax toxin receptor 2 |
| Description
| Not Available |
| Synonyms
|
- CMG-2
- Capillary morphogenesis gene 2 protein
|
| Gene Name
| ANTXR2 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in metal ion binding |
| Specific Function
| Necessary for cellular interactions with laminin and the extracellular matrix |
| GO Classification
|
| Component |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| cell part |
| Function |
| receptor activity |
| molecular transducer activity |
| signal transducer activity |
|
| Cellular Location
|
- Isoform 3:Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:4 |
| Locus
| 4q21.21 |
| SNPs
| ANTXR2 |
| Gene Sequence
|
>1470 bp
ATGGTGGCGGAGCGGTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGG
CTGTTGGTGCTCAGCGGTCCCGGGGGGCTGCTGCGCGCCCAGGAGCAGCCCTCCTGCAGA
AGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATT
GAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTA
TCTTTCATTGTGTTTTCTTCTCAAGCAACTATTATTTTGCCATTAACTGGAGACAGAGGC
AAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATC
CATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCC
AGTATCATAATTGCTCTGACAGATGGCAAGTTGGACGGTCTGGTGCCATCATATGCAGAG
AAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGAT
TTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAA
GGTGGATTTCAGGCTCTTAAAGGAATAATTAATTCTATACTAGCTCAGTCATGTACTGAA
ATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGT
GGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAAT
GAAACATATACAACGAGTGTAAAACCAGTAAGTGTACAGCTTAATTCTATGCTTTGTCCT
GCACCTATCCTGAATAAAGCTGGAGAAACTCTTGATGTTTCAGTGAGCTTTAATGGAGGA
AAATCTGTCATTTCAGGATCATTAATTGTCACAGCCACAGAATGTTCTAACGGGATCGCA
GCCATCATTGTTATTTTGGTGTTACTGCTACTCCTGGGGATCGGTTTGATGTGGTGGTTT
TGGCCCCTTTGCTGCAAAGTGGTTATTAAGGATCCTCCACCACCACCCGCCCCTGCACCA
AAAGAGGAGGAAGAAGAACCTTTGCCTACTAAAAAGTGGCCAACTGTGGATGCTTCCTAT
TATGGTGGTCGAGGGGTTGGAGGAATTAAAAGAATGGAGGTTCGTTGGGGTGATAAAGGA
TCTACTGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATGCTGTGGTGAAGATTCCTGAA
GAAACAGAGGAACCCATCAGGCCTAGACCACCTCGACCCAAACCCACACACCAGCCTCCT
CAGACAAAATGGTACACCCCAATTAAGGGTCGTCTTGATGCTCTCTGGGCTTTGTTGAGG
CGGCAGTATGACCGGGTTTCTTTGATGCGACCTCAGGAAGGAGATGAGGTTTGTATATGG
GAATGTATTGAGAAAGAGCTAACTGCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 489 |
| Molecular Weight
| 53665.7 |
| Theoretical pI
| 7.53 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Anthrax toxin receptor 2
MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWI
EIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYI
HEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD
FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLS
GRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGG
KSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAP
KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPE
ETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEVCIW
ECIEKELTA
|
| External Links |
|---|
| GenBank ID Protein
| 224809466 |
| UniProtKB/Swiss-Prot ID
| P58335 |
| UniProtKB/Swiss-Prot Entry Name
| ANTR2_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| NM_001145794.1 |
| GeneCard ID
| ANTXR2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |