| Identification |
|---|
| HMDB Protein ID
| CDBP02656 |
| Secondary Accession Numbers
| Not Available |
| Name
| Anoctamin-3 |
| Description
| Not Available |
| Synonyms
|
- Transmembrane protein 16C
|
| Gene Name
| ANO3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in chloride channel activity |
| Specific Function
| May act as a calcium-activated chloride channel |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11p14.2 |
| SNPs
| ANO3 |
| Gene Sequence
|
>2946 bp
ATGGTCCACCATTCAGGCTCCATTCAGTCCTTTAAACAGCAAAAAGGTATGAATATAAGC
AAGAGTGAGATAACAAAAGAAACTTCGTTAAAACCGTCTCGGAGATCCCTGCCTTGCCTC
GCCCAGAGCTACGCTTACTCAAAGAGCTTGAGCCAGTCTACTTCCCTCTTCCAGTCAACC
GAGAGTGAATCTCAGGCTCCCACATCTATAACCTTAATCTCCACTGACAAAGCAGAGCAA
GTTAATACTGAGGAGAATAAAAACGACTCTGTGCTGAGATGTTCATTTGCTGACCTCAGC
GATTTTTGTTTGGCCCTAGGAAAAGATAAGGATTACACGGATGAATCAGAACACGCTACT
TATGACCGATCTCGTCTCATTAATGACTTTGTTATCAAAGATAAATCTGAATTCAAGACA
AAATTATCTAAGAATGACATGAATTACATAGCATCCAGTGGACCTCTGTTCAAAGATGGC
AAAAAGAGAATTGATTACATCTTGGTTTATAGAAAGACAAATATACAATATGATAAAAGA
AACACATTTGAAAAGAACCTCAGAGCAGAAGGCTTGATGTTGGAGAAGGAGCCAGCTATT
GCAAGCCCCGATATCATGTTTATTAAAATTCACATTCCATGGGACACGCTGTGCAAGTAT
GCAGAGAGGCTGAATATCAGGATGCCCTTCAGGAAAAAATGCTATTACACTGACGGGAGG
AGCAAATCAATGGGCAGGATGCAAACTTATTTTAGAAGAATCAAAAACTGGATGGCCCAA
AACCCAATGGTTCTTGACAAGTCAGCTTTTCCAGACCTAGAGGAGTCAGACTGCTATACT
GGCCCCTTCAGCCGTGCACGGATTCACCACTTCATAATAAATAATAAAGACACCTTCTTC
AGCAATGCTACTCGAAGCAGAATAGTCTATCACATGCTGGAACGCACCAAATATGAAAAT
GGAATATCAAAAGTGGGTATCCGTAAACTTATAAACAATGGCTCATACATAGCAGCGTTT
CCACCACATGAGGGAGCCTACAAAAGTAGCCAGCCCATTAAAACCCATGGACCTCAGAAT
AACAGACATCTATTATATGAGCGCTGGGCACGCTGGGGAATGTGGTATAAGCATCAGCCT
CTGGATTTAATCAGGCTATACTTTGGTGAGAAGATTGGACTATACTTTGCTTGGCTGGGA
TGGTATACTGGAATGTTGATTCCTGCAGCAATTGTTGGTTTGTGCGTTTTCTTCTATGGA
TTATTTACAATGAATAATAGTCAAGTAAGCCAAGAAATTTGTAAAGCCACTGAAGTCTTT
ATGTGCCCTCTCTGTGACAAGAACTGCTCCCTGCAGAGACTCAACGACAGCTGTATCTAT
GCCAAGGTGACATATTTGTTCGATAATGGAGGGACAGTCTTCTTTGCTATTTTTATGGCA
ATATGGGCCACAGTCTTCCTGGAGTTTTGGAAAAGGAGAAGGAGTATACTGACCTATACT
TGGGACCTTATCGAATGGGAAGAAGAGGAGGAAACACTTCGTCCCCAGTTTGAAGCCAAG
TATTACAAGATGGAGATTGTAAATCCCATCACGGGAAAACCTGAACCACATCAGCCTTCC
TCAGACAAAGTCACTCGTCTTCTTGTTTCTGTCTCAGGAATATTCTTCATGATATCCTTG
GTGATCACTGCAGTGTTTGGAGTTGTGGTGTACCGCCTGGTTGTCATGGAACAGTTTGCA
TCATTCAAGTGGAATTTCATCAAACAATACTGGCAGTTTGCAACATCTGCTGCTGCTGTC
TGTATCAATTTCATAATCATTATGTTGCTGAATCTTGCTTATGAAAAAATTGCTTACCTC
CTCACCAATTTAGAATATCCTCGAACAGAATCAGAGTGGGAAAACAGCTTCGCCCTGAAG
ATGTTCCTCTTCCAGTTTGTCAATTTAAACAGTTCCATCTTCTATATCGCTTTCTTTTTG
GGAAGATTCGTAGGCCACCCAGGAAAATACAATAAACTTTTTGACCGGTGGAGACTGGAG
GAATGTCATCCTAGTGGCTGTTTGATAGACCTCTGCCTCCAGATGGGTGTCATCATGTTT
TTGAAGCAAATATGGAACAACTTCATGGAACTAGGATACCCGTTGATCCAGAACTGGTGG
TCACGACATAAAATCAAGCGGGGAATACATGATGCTTCCATACCTCAGTGGGAAAATGAT
TGGAATCTGCAGCCCATGAACCTTCATGGACTGATGGATGAGTACTTAGAAATGGTTTTG
CAATTTGGTTTTACCACCATCTTTGTTGCGGCTTTTCCTCTAGCCCCTCTTTTGGCTTTG
TTAAACAATATCATTGAAATCAGGCTGGATGCATACAAATTTGTCACTCAATGGCGGAGG
CCTTTGCCAGCCCGAGCAACTGACATAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGT
ATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGT
TTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGC
TTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGA
AAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTAT
GAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTT
GAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAG
GGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCT
GAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGG
CCTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 981 |
| Molecular Weight
| 114655.5 |
| Theoretical pI
| 8.84 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["404-424", "470-490", "551-571", "593-613", "641-661", "762-782", "811-831", "915-935"]
|
| Protein Sequence
|
>Anoctamin-3
MVHHSGSIQSFKQQKGMNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQST
ESESQAPTSITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHAT
YDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQYDKR
NTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGR
SKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFF
SNATRSRIVYHMLERTKYENGISKVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQN
NRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYG
LFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMA
IWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPS
SDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAV
CINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFL
GRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWW
SRHKIKRGIHDASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLAL
LNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPR
FVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPY
EFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEA
ELEHLQQQRRKSGQPVHHEWP
|
| External Links |
|---|
| GenBank ID Protein
| 156766084 |
| UniProtKB/Swiss-Prot ID
| Q9BYT9 |
| UniProtKB/Swiss-Prot Entry Name
| ANO3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_031418.2 |
| GeneCard ID
| ANO3 |
| GenAtlas ID
| ANO3 |
| HGNC ID
| HGNC:14004 |
| References |
|---|
| General References
| Not Available |