| Identification |
|---|
| HMDB Protein ID
| CDBP02636 |
| Secondary Accession Numbers
| Not Available |
| Name
| 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- Ubiquinone biosynthesis methyltransferase COQ5
|
| Gene Name
| COQ5 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in methyltransferase activity |
| Specific Function
| Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity).
|
| GO Classification
|
| Biological Process |
| ubiquinone biosynthetic process |
| Cellular Component |
| mitochondrion |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring one-carbon groups |
| methyltransferase activity |
| Molecular Function |
| methyltransferase activity |
|
| Cellular Location
|
- Mitochondrion
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Ubiquinone Biosynthesis |    |  | | Ubiquinone and other terpenoid-quinone biosynthesis | Not Available | |
|
| Gene Properties |
|---|
| Chromosome Location
| 12 |
| Locus
| 12q24.31 |
| SNPs
| COQ5 |
| Gene Sequence
|
>984 bp
ATGGCGGCCCCCGGGAGCTGTGCTCTATGGAGCTATTGCGGCCGTGGGTGGTCGCGGGCG
ATGCGGGGCTGCCAGCTCCTCGGGCTTCGTAGCTCTTGGCCCGGGGACCTACTAAGTGCT
CGGCTCTTGTCCCAAGAGAAGCGGGCAGCGGAAACGCACTTTGGGTTTGAGACTGTGTCG
GAAGAGGAGAAGGGGGGCAAAGTCTATCAGGTGTTTGAAAGTGTGGCTAAGAAGTATGAT
GTGATGAATGATATGATGAGTCTTGGTATCCATCGTGTTTGGAAGGATTTGCTGCTCTGG
AAGATGCACCCGCTTCCTGGGACCCAGCTGCTTGATGTTGCTGGAGGCACAGGTGACATT
GCATTCCGGTTCCTTAATTATGTTCAGTCCCAGCATCAGAGAAAACAGAAGAGGCAGTTA
AGGGCCCAACAAAATTTATCCTGGGAAGAAATTGCCAAAGAGTACCAGAATGAAGAAGAT
TCCTTGGGCGGGTCTCGTGTCGTGGTGTGTGACATCAACAAGGAGATGCTAAAGGTTGGA
AAGCAGAAAGCCTTGGCTCAAGGATACAGAGCTGGACTTGCATGGGTATTAGGAGATGCT
GAAGAACTGCCCTTTGATGATGACAAGTTTGATATTTACACCATTGCCTTTGGGATCCGG
AATGTCACACACATTGATCAGGCACTCCAGGAAGCTCATCGGGTGCTGAAACCAGGAGGA
CGGTTTCTCTGTCTGGAATTTAGCCAAGTGAACAATCCCCTCATATCCAGGCTTTATGAT
CTATATAGCTTCCAGGTCATCCCTGTCCTGGGAGAGGTCATCGCTGGAGACTGGAAGTCC
TATCAGTACCTTGTAGAGAGTATCCGAAGGTTTCCGTCTCAGGAAGAGTTCAAGGACATG
ATAGAAGATGCAGGCTTTCACAAGGTGACTTACGAAAGTCTAACATCAGGCATTGTGGCC
ATTCATTCTGGCTTCAAACTTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 327 |
| Molecular Weight
| 37140.17 |
| Theoretical pI
| 6.942 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ubiquinone biosynthesis methyltransferase COQ5, mitochondrial
MAAPGSCALWSYCGRGWSRAMRGCQLLGLRSSWPGDLLSARLLSQEKRAAETHFGFETVS
EEEKGGKVYQVFESVAKKYDVMNDMMSLGIHRVWKDLLLWKMHPLPGTQLLDVAGGTGDI
AFRFLNYVQSQHQRKQKRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKEMLKVG
KQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGG
RFLCLEFSQVNNPLISRLYDLYSFQVIPVLGEVIAGDWKSYQYLVESIRRFPSQEEFKDM
IEDAGFHKVTYESLTSGIVAIHSGFKL
|
| External Links |
|---|
| GenBank ID Protein
| 116063536 |
| UniProtKB/Swiss-Prot ID
| Q5HYK3 |
| UniProtKB/Swiss-Prot Entry Name
| COQ5_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_032314.3 |
| GeneCard ID
| COQ5 |
| GenAtlas ID
| COQ5 |
| HGNC ID
| HGNC:28722 |
| References |
|---|
| General References
| Not Available |