Identification
HMDB Protein ID CDBP02598
Secondary Accession Numbers Not Available
Name Probable arginine--tRNA ligase, mitochondrial
Description Not Available
Synonyms
  1. ArgRS
  2. Arginine--tRNA ligase
  3. Arginyl-tRNA synthetase-like
  4. Arginyl-tRNA synthetase
Gene Name RARS2
Protein Type Enzyme
Biological Properties
General Function Involved in nucleotide binding
Specific Function Not Available
GO Classification
Biological Process
tRNA aminoacylation for protein translation
arginyl-tRNA aminoacylation
Cellular Component
mitochondrial matrix
Component
cell part
intracellular part
cytoplasm
Function
ligase activity
arginine-trna ligase activity
ligase activity, forming carbon-oxygen bonds
ligase activity, forming aminoacyl-trna and related compounds
aminoacyl-trna ligase activity
binding
nucleotide binding
catalytic activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
Molecular Function
ATP binding
arginine-tRNA ligase activity
Process
macromolecule metabolic process
cellular macromolecule metabolic process
arginyl-trna aminoacylation
biosynthetic process
rna metabolic process
ncrna metabolic process
trna metabolic process
trna aminoacylation
trna aminoacylation for protein translation
macromolecule biosynthetic process
cellular macromolecule biosynthetic process
translation
metabolic process
Cellular Location
  1. Mitochondrion matrix
Pathways
Gene Properties
Chromosome Location 6
Locus 6q16.1
SNPs RARS2
Gene Sequence
>1737 bp
ATGGCGTGCGGCTTTCGCCGCGCTATTGCTTGCCAGCTTTCCAGAGTGTTGAATCTTCCA
CCAGAAAACTTGATCACATCAATATCTGCAGTTCCAATTTCCCAAAAAGAAGAAGTAGCT
GATTTTCAGCTTTCTGTGGATCCTTTATTGGAAAAAGACAATGACCATTCAAGACCAGAT
ATTCAAGTTCAAGCCAAGAGACTAGCAGAGAAGCTAAGATGTGATACAGTGGTGAGTGAA
ATCAGTACTGGTCAAAGGACTGTAAATTTCAAAATAAACAGAGAGCTCTTAACAAAGACA
GTGCTACAACAAGTAATTGAAGATGGCTCAAAATATGGATTAAAAAGTGAACTTTTCTCT
GGACTTCCCCAGAAGAAGATTGTGGTTGAATTCAGTTCACCTAATGTTGCCAAAAAATTT
CATGTTGGACATTTGCGTTCTACCGTCATAGGAAATTTTATAGCAAATCTCAAAGAAGCT
TTAGGACATCAAGTAATAAGAATAAATTACCTTGGCGATTGGGGCATGCAGTTTGGTCTT
CTGGGAACTGGCTTCCAGCTGTTTGGCTATGAGGAAAAACTGCAGTCCAATCCTCTACAG
CATCTCTTTGAAGTTTATGTACAAGTTAATAAAGAAGCAGCGGATGATAAAAGTGTAGCA
AAAGCAGCACAGGAGTTCTTCCAACGATTGGAACTGGGCGATGTGCAAGCACTTTCACTG
TGGCAAAAATTTCGGGACTTGAGCATTGAAGAGTACATTCGGGTTTACAAGCGTCTGGGA
GTATATTTTGATGAATATTCAGGAGAATCATTTTATCGTGAAAAATCTCAAGAGGTCTTA
AAGTTGCTGGAGAGTAAAGGACTCCTACTGAAAACAATAAAAGGAACGGCTGTAGTAGAT
CTCTCTGGGAATGGCGACCCCTCCTCAATTTGTACTGTAATGCGAAGTGATGGGACTTCT
CTCTATGCAACCAGAGATCTTGCAGCTGCTGTAGATCGAATGGACAAGTATAATTTTGAT
ACAATGATATATGTGACAGATAAAGGACAAAAAAAGCATTTTCAGCAAGTATTCCAAATG
CTGAAGATCATGGGATATGACTGGGCAGAAAGGTGCCAGCACGTGCCCTTTGGAGTAGTA
CAGGGAATGAAGACTCGAAGAGGAGATGTCACTTTCCTGGAAGATGTTTTAAATGAGATT
CAATTAAGGATGCTACAGAACATGGCTTCAATTAAGACAACTAAAGAACTCAAGAACCCA
CAAGAGACTGCAGAGAGGGTCGGGCTCGCAGCACTCATTATTCAGGACTTCAAAGGTTTA
CTCTTATCTGACTACAAGTTCAGCTGGGATCGTGTTTTCCAGAGTCGCGGGGACACAGGA
GTCTTCCTACAGTACACACACGCCCGCCTCCACAGTTTGGAAGAGACTTTTGGATGTGGG
TACCTGAATGACTTCAACACTGCTTGTTTACAAGAGCCACAGTCTGTTTCAATTCTTCAG
CATCTTCTCAGGTTCGACGAGGTGCTTTATAAATCATCTCAGGACTTTCAACCCAGGCAT
ATCGTCAGTTACCTTCTAACTTTAAGTCATCTTGCAGCTGTGGCACACAAAACACTACAA
ATAAAAGATAGTCCTCCTGAAGTGGCTGGGGCCAGACTTCATCTTTTCAAAGCTGTCCGT
TCTGTCCTAGCCAATGGAATGAAACTTCTTGGAATAACACCTGTATGTAGGATGTAA
Protein Properties
Number of Residues 578
Molecular Weight 65504.855
Theoretical pI 8.212
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Probable arginyl-tRNA synthetase, mitochondrial
MACGFRRAIACQLSRVLNLPPENLITSISAVPISQKEEVADFQLSVDSLLEKDNDHSRPD
IQVQAKRLAEKLRCDTVVSEISTGQRTVNFKINRELLTKTVLQQVIEDGSKYGLKSELFS
GLPQKKIVVEFSSPNVAKKFHVGHLRSTIIGNFIANLKEALGHQVIRINYLGDWGMQFGL
LGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKEAADDKSVAKAAQEFFQRLELGDVQALSL
WQKFRDLSIEEYIRVYKRLGVYFDEYSGESFYREKSQEVLKLLESKGLLLKTIKGTAVVD
LSGNGDPSSICTVMRSDGTSLYATRDLAAAIDRMDKYNFDTMIYVTDKGQKKHFQQVFQM
LKIMGYDWAERCQHVPFGVVQGMKTRRGDVTFLEDVLNEIQLRMLQNMASIKTTKELKNP
QETAERVGLAALIIQDFKGLLLSDYKFSWDRVFQSRGDTGVFLQYTHARLHSLEETFGCG
YLNDFNTACLQEPQSVSILQHLLRFDEVLYKSSQDFQPRHIVSYLLTLSHLAAVAHKTLQ
IKDSPPEVAGARLHLFKAVRSVLANGMKLLGITPVCRM
GenBank ID Protein 10435519
UniProtKB/Swiss-Prot ID Q5T160
UniProtKB/Swiss-Prot Entry Name SYRM_HUMAN
PDB IDs Not Available
GenBank Gene ID AK023550
GeneCard ID RARS2
GenAtlas ID RARS2
HGNC ID HGNC:21406
References
General References Not Available