Identification |
HMDB Protein ID
| CDBP02565 |
Secondary Accession Numbers
| Not Available |
Name
| Phosphatidylinositol-glycan biosynthesis class F protein |
Description
| Not Available |
Synonyms
|
- GPI11 homolog
- PIG-F
|
Gene Name
| PIGF |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GPI anchor biosynthetic process |
Specific Function
| Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI |
GO Classification
|
Component |
intrinsic to membrane |
integral to membrane |
membrane |
cell part |
endoplasmic reticulum membrane |
membrane part |
organelle membrane |
Process |
metabolic process |
macromolecule metabolic process |
protein amino acid lipidation |
gpi anchor biosynthetic process |
macromolecule modification |
protein modification process |
|
Cellular Location
|
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 2p21-p16 |
SNPs
| PIGF |
Gene Sequence
|
>660 bp
ATGAAAGATAACGATATCAAGAGACTACTGTATACCCATCTTTTATGCATATTTTCAATT
ATCCTAAGTGTCTTCATTCCATCACTCTTCTTGGAGAACTTCTCAATATTGGAAACACAC
TTGACATGGTTGTGCATCTGTTCTGGTTTTGTAACTGCTGTCAATCTAGTACTATATTTA
GTAGTGAAACCAAATACATCCTCTAAAAGAAGTTCATTATCACACAAGGTAACTGGATTT
TTGAAATGCTGTATCTACTTTCTTATGTCTTGTTTCTCCTTTCATGTAATTTTTGTTCTG
TATGGAGCACCACTGATAGAGTTGGCATTGGAAACATTTTTATTTGCAGTTATTTTGTCT
ACTTTTACTACTGTGCCTTGCTTATGTTTGTTAGGACCAAACCTCAAAGCATGGCTAAGA
GTGTTCAGTAGAAATGGAGTTACATCCATATGGGAGAATAGTCTCCAGATCACTACAATT
TCTAGCTTTGTAGGAGCATGGCTTGGAGCACTTCCTATTCCACTGGATTGGGAAAGACCA
TGGCAGGTATGGCCCATCTCCTGTACGCTTGGAGCGACCTTTGGCTACGTGGCTGGCCTT
GTTATTTCACCACTCTGGATATACTGGAATAGAAAGCAACTTACATACAAGAACAATTAA
|
Protein Properties |
Number of Residues
| 219 |
Molecular Weight
| 24889.3 |
Theoretical pI
| 8.64 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
- ["11-31", "42-62", "86-106", "113-133", "155-175", "189-209"]
|
Protein Sequence
|
>Phosphatidylinositol-glycan biosynthesis class F protein
MKDNDIKRLLYTHLLCIFSIILSVFIPSLFLENFSILETHLTWLCICSGFVTAVNLVLYL
VVKPNTSSKRSSLSHKVTGFLKCCIYFLMSCFSFHVIFVLYGAPLIELALETFLFAVILS
TFTTVPCLCLLGPNLKAWLRVFSRNGVTSIWENSLQITTISSFVGAWLGALPIPLDWERP
WQVWPISCTLGATFGYVAGLVISPLWIYWNRKQLTYKNN
|
External Links |
GenBank ID Protein
| 4505797 |
UniProtKB/Swiss-Prot ID
| Q07326 |
UniProtKB/Swiss-Prot Entry Name
| PIGF_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_002643.3 |
GeneCard ID
| PIGF |
GenAtlas ID
| PIGF |
HGNC ID
| HGNC:8962 |
References |
General References
| Not Available |