Identification
HMDB Protein ID CDBP02565
Secondary Accession Numbers Not Available
Name Phosphatidylinositol-glycan biosynthesis class F protein
Description Not Available
Synonyms
  1. GPI11 homolog
  2. PIG-F
Gene Name PIGF
Protein Type Enzyme
Biological Properties
General Function Involved in GPI anchor biosynthetic process
Specific Function Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI
GO Classification
Component
intrinsic to membrane
integral to membrane
membrane
cell part
endoplasmic reticulum membrane
membrane part
organelle membrane
Process
metabolic process
macromolecule metabolic process
protein amino acid lipidation
gpi anchor biosynthetic process
macromolecule modification
protein modification process
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2p21-p16
SNPs PIGF
Gene Sequence
>660 bp
ATGAAAGATAACGATATCAAGAGACTACTGTATACCCATCTTTTATGCATATTTTCAATT
ATCCTAAGTGTCTTCATTCCATCACTCTTCTTGGAGAACTTCTCAATATTGGAAACACAC
TTGACATGGTTGTGCATCTGTTCTGGTTTTGTAACTGCTGTCAATCTAGTACTATATTTA
GTAGTGAAACCAAATACATCCTCTAAAAGAAGTTCATTATCACACAAGGTAACTGGATTT
TTGAAATGCTGTATCTACTTTCTTATGTCTTGTTTCTCCTTTCATGTAATTTTTGTTCTG
TATGGAGCACCACTGATAGAGTTGGCATTGGAAACATTTTTATTTGCAGTTATTTTGTCT
ACTTTTACTACTGTGCCTTGCTTATGTTTGTTAGGACCAAACCTCAAAGCATGGCTAAGA
GTGTTCAGTAGAAATGGAGTTACATCCATATGGGAGAATAGTCTCCAGATCACTACAATT
TCTAGCTTTGTAGGAGCATGGCTTGGAGCACTTCCTATTCCACTGGATTGGGAAAGACCA
TGGCAGGTATGGCCCATCTCCTGTACGCTTGGAGCGACCTTTGGCTACGTGGCTGGCCTT
GTTATTTCACCACTCTGGATATACTGGAATAGAAAGCAACTTACATACAAGAACAATTAA
Protein Properties
Number of Residues 219
Molecular Weight 24889.3
Theoretical pI 8.64
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["11-31", "42-62", "86-106", "113-133", "155-175", "189-209"]
Protein Sequence
>Phosphatidylinositol-glycan biosynthesis class F protein
MKDNDIKRLLYTHLLCIFSIILSVFIPSLFLENFSILETHLTWLCICSGFVTAVNLVLYL
VVKPNTSSKRSSLSHKVTGFLKCCIYFLMSCFSFHVIFVLYGAPLIELALETFLFAVILS
TFTTVPCLCLLGPNLKAWLRVFSRNGVTSIWENSLQITTISSFVGAWLGALPIPLDWERP
WQVWPISCTLGATFGYVAGLVISPLWIYWNRKQLTYKNN
GenBank ID Protein 4505797
UniProtKB/Swiss-Prot ID Q07326
UniProtKB/Swiss-Prot Entry Name PIGF_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_002643.3
GeneCard ID PIGF
GenAtlas ID PIGF
HGNC ID HGNC:8962
References
General References Not Available