| Identification |
|---|
| HMDB Protein ID
| CDBP02556 |
| Secondary Accession Numbers
| Not Available |
| Name
| Lipase member H |
| Description
| Not Available |
| Synonyms
|
- LPD lipase-related protein
- Membrane-associated phosphatidic acid-selective phospholipase A1-alpha
- Phospholipase A1 member B
- mPA-PLA1 alpha
|
| Gene Name
| LIPH |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Hydrolyzes specifically phosphatidic acid (PA) to produce lysophosphatidic acid (LPA) |
| GO Classification
|
| Function |
| catalytic activity |
| Process |
| metabolic process |
| primary metabolic process |
| lipid metabolic process |
|
| Cellular Location
|
- Peripheral membrane protein
- Secreted
- Membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q27 |
| SNPs
| LIPH |
| Gene Sequence
|
>1356 bp
ATGTTGAGATTCTACTTATTCATCAGTTTGTTGTGCTTGTCAAGATCAGACGCAGAAGAA
ACATGTCCTTCATTCACCAGGCTGAGCTTTCACAGTGCAGTGGTTGGTACGGGACTAAAT
GTGAGGCTGATGCTCTACACAAGGAAAAACCTGACCTGCGCACAAACCATCAACTCCTCA
GCTTTTGGGAACTTGAATGTGACCAAGAAAACCACCTTCATTGTCCATGGATTCAGGCCA
ACAGGCTCCCCTCCTGTTTGGATGGATGACTTAGTAAAGGGTTTGCTCTCTGTTGAAGAC
ATGAACGTAGTTGTTGTTGATTGGAATCGAGGAGCTACAACTTTAATATATACCCATGCC
TCTAGTAAGACCAGAAAAGTAGCCATGGTCTTGAAGGAATTTATTGACCAGATGTTGGCA
GAAGGAGCTTCTCTTGATGACATTTACATGATCGGAGTAAGTCTAGGAGCCCACATATCT
GGGTTTGTTGGAGAGATGTACGATGGATGGCTGGGGAGAATTACAGGCCTCGACCCTGCA
GGCCCTTTATTCAACGGGAAACCTCACCAAGACAGATTAGATCCCAGTGATGCGCAGTTT
GTTGATGTCATCCATTCCGACACTGATGCACTGGGCTACAAGGAGCCATTAGGAAACATA
GACTTCTACCCAAATGGAGGATTGGATCAACCTGGCTGCCCCAAAACAATATTGGGAGGA
TTTCAGTATTTTAAATGTGACCACCAGAGGTCTGTATACCTGTACCTGTCTTCCCTGAGA
GAGAGCTGCACCATCACTGCGTATCCCTGTGACTCCTACCAGGATTATAGGAATGGCAAG
TGTGTCAGCTGCGGCACGTCACAAAAAGAGTCCTGTCCCCTTCTGGGCTATTATGCTGAT
AATTGGAAAGACCATCTAAGGGGGAAAGATCCTCCAATGACGAAGGCATTCTTTGACACA
GCTGAGGAGAGCCCATTCTGCATGTATCATTACTTTGTGGATATTATAACATGGAACAAG
AATGTAAGAAGAGGGGACATTACCATCAAATTGAGAGACAAAGCTGGAAACACCACAGAA
TCCAAAATCAATCATGAACCCACCACATTTCAGAAATATCACCAAGTGAGTCTACTTGCA
AGATTTAATCAAGATCTGGATAAAGTGGCTGCAATTTCCTTGATGTTCTCTACAGGATCT
CTAATAGGCCCAAGGTACAAGCTCAGGATTCTCCGAATGAAGTTAAGGTCCCTTGCCCAT
CCGGAGAGGCCTCAGCTGTGTCGGTATGATCTTGTCCTGATGGAAAACGTTGAAACAGTC
TTCCAACCTATTCTTTGCCCAGAGTTGCAGTTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 451 |
| Molecular Weight
| 50858.9 |
| Theoretical pI
| 7.46 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Lipase member H
MLRFYLFISLLCLSRSDAEETCPSFTRLSFHSAVVGTGLNVRLMLYTRKNLTCAQTINSS
AFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVEDMNVVVVDWNRGATTLIYTHA
SSKTRKVAMVLKEFIDQMLAEGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPA
GPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNGGLDQPGCPKTILGG
FQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGTSQKESCPLLGYYAD
NWKDHLRGKDPPMTKAFFDTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRDKAGNTTE
SKINHEPTTFQKYHQVSLLARFNQDLDKVAAISLMFSTGSLIGPRYKLRILRMKLRSLAH
PERPQLCRYDLVLMENVETVFQPILCPELQL
|
| External Links |
|---|
| GenBank ID Protein
| 21245106 |
| UniProtKB/Swiss-Prot ID
| Q8WWY8 |
| UniProtKB/Swiss-Prot Entry Name
| LIPH_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_139248.2 |
| GeneCard ID
| LIPH |
| GenAtlas ID
| LIPH |
| HGNC ID
| HGNC:18483 |
| References |
|---|
| General References
| Not Available |