2527 CDBP02526 Lysophospholipid acyltransferase 5 Q6P1A2 MBOA5_HUMAN true false Enzyme Homo_sapiens LPCAT3 487 56034.48 8.692 Involved in 1-acylglycerophosphocholine O-acyltransfera Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. NM_005768.5 42542394 LPCAT3 12 12p13 LPCAT3 HGNC:30244 true hsa:10162 NP_005759.4:NM_005768.5 Highly expressed in liver, pancreas and adipose tissue. Very low expression in skeletal muscle and heart. Detected in neutrophils. 2020-06-12T23:07:05Z 2020-06-12T23:07:05Z 0 0 0