2518 CDBP02517 Acyl-CoA wax alcohol acyltransferase 1 Q58HT5 AWAT1_HUMAN true false Enzyme Homo_sapiens AWAT1 328 37758.815 8.84 Involved in transferase activity, transferring acyl groups other than amino-acyl groups Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20). AL357752 123227401 AWAT1 X Xq13.1 AWAT1 HGNC:23252 true hsa:158833 NP_001013597.1:NM_001013579.2 Predominantly expressed in skin, where it is limited to the sebaceous gland. Expressed in more mature, centrally located cells just before their rupture and sebum release. Also expressed in all tissues except spleen. Expressed at higher level in thymus, prostate and testis. 2020-06-12T23:07:05Z 2020-06-12T23:07:05Z 0 0 0