Identification |
HMDB Protein ID
| CDBP02516 |
Secondary Accession Numbers
| Not Available |
Name
| Aldose 1-epimerase |
Description
| Not Available |
Synonyms
|
- Galactose mutarotase
- SubName: Putative uncharacterized protein LOC130589
- SubName: cDNA FLJ75695, highly similar to Homo sapiens galactose mutarotase (aldose 1-epimerase) (GALM), mRNA
|
Gene Name
| GALM |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in isomerase activity |
Specific Function
| Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity).
|
GO Classification
|
Biological Process |
hexose metabolic process |
Cellular Component |
cytoplasm |
Function |
isomerase activity |
carbohydrate binding |
binding |
catalytic activity |
Molecular Function |
carbohydrate binding |
aldose 1-epimerase activity |
Process |
metabolic process |
primary metabolic process |
carbohydrate metabolic process |
small molecule metabolic process |
alcohol metabolic process |
monosaccharide metabolic process |
hexose metabolic process |
|
Cellular Location
|
- Cytoplasm (Probable)
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Glycolysis | | | Gluconeogenesis | | | hexose metabolism | Not Available | Not Available | Glycolysis / Gluconeogenesis | Not Available | | Glycogenosis, Type VII. Tarui disease | | Not Available |
|
Gene Properties |
Chromosome Location
| 2 |
Locus
| 2p22.1 |
SNPs
| GALM |
Gene Sequence
|
>1029 bp
ATGGCTTCGGTGACCAGGGCCGTGTTTGGAGAGCTGCCCTCGGGAGGAGGGACAGTGGAG
AAGTTCCAGCTGCAGTCAGACCTCTTGAGAGTGGACATCATCTCCTGGGGCTGCACGATC
ACAGCCCTAGAGGTCAAAGACAGGCAGGGGAGAGCCTCGGACGTGGTGCTTGGCTTCGCC
GAGTTGGAAGGATACCTCCAAAAGCAGCCATACTTTGGAGCAGTTATTGGGAGGGTGGCC
AACCGAATCGCCAAAGGAACCTTCAAGGTGGATGGGAAGGAGTATCACCTGGCCATTAAC
AAGGAACCCAACAGTCTGCATGGAGGAGTCAGAGGGTTTGATAAAGTGCTCTGGACCCCT
CGGGTGCTGTCAAATGGCGTCCAGTTCTCGCGCATCAGTCCAGATGGTGAAGAAGGCTAC
CCCGGAGAGTTAAAAGTCTGGGTGACATACACCCTGGATGGCGGAGAGCTCATAGTCAAC
TACAGAGCACAAGCCAGTCAGGCCACACCAGTCAACCTGACCAACCATTCTTACTTCAAC
CTGGCAGGCCAGGCTTCCCCAAATATAAATGACCATGAAGTCACCATAGAAGCGGATACT
TATTTGCCTGTGGATGAAACCCTGATTCCTACAGGAGAAGTTGCCCCAGTGCAAGGCACT
GCATTCGACCTGAGAAAGCCAGTGGAGCTTGGAAAACACCTGCAGGACTTCCATCTCAAT
GGTTTTGACCACAATTTCTGTCTGAAGGGATCTAAAGAAAAGCATTTTTGTGCAAGGGTG
CATCATGCTGCAAGCGGGCGGGTACTAGAAGTATACACCACCCAGCCCGGGGTCCAGTTT
TACACGGGCAACTTCCTGGATGGCACATTAAAGGGCAAGAATGGAGCTGTCTATCCCAAG
CACTCCGGTTTCTGCCTGGAGACTCAGAACTGGCCTGATGCAGTCAATCAGCCCCGCTTC
CCTCCTGTGCTGCTGAGGCCTGGTGAGGAGTATGACCACACCACCTGGTTCAAGTTTTCT
GTGGCTTAA
|
Protein Properties |
Number of Residues
| 342 |
Molecular Weight
| 37765.365 |
Theoretical pI
| 6.66 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Aldose 1-epimerase
MASVTRAVFGELPSGGGTVEKFQLQSDLLRVDIISWGCTITALEVKDRQGRASDVVLGFA
ELEGYLQKQPYFGAVIGRVANRIAKGTFKVDGKEYHLAINKEPNSLHGGVRGFDKVLWTP
RVLSNGVQFSRISPDGEEGYPGELKVWVTYTLDGGELIVNYRAQASQATPVNLTNHSYFN
LAGQASPNINDHEVTIEADTYLPVDETLIPTGEVAPVQGTAFDLRKPVELGKHLQDFHLN
GFDHNFCLKGSKEKHFCARVHHAASGRVLEVYTTQPGVQFYTGNFLDGTLKGKNGAVYPK
HSGFCLETQNWPDAVNQPRFPPVLLRPGEEYDHTTWFKFSVA
|
External Links |
GenBank ID Protein
| 20530222 |
UniProtKB/Swiss-Prot ID
| Q96C23 |
UniProtKB/Swiss-Prot Entry Name
| GALM_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AY064382 |
GeneCard ID
| GALM |
GenAtlas ID
| GALM |
HGNC ID
| HGNC:24063 |
References |
General References
| Not Available |