Identification
HMDB Protein ID CDBP02488
Secondary Accession Numbers Not Available
Name Cytochrome c oxidase subunit 3
Description Not Available
Synonyms
  1. Cytochrome c oxidase polypeptide III
Gene Name MT-CO3
Protein Type Enzyme
Biological Properties
General Function Involved in cytochrome-c oxidase activity
Specific Function Subunits I, II and III form the functional core of the enzyme complex
GO Classification
Component
membrane
cell part
Function
cytochrome-c oxidase activity
catalytic activity
oxidoreductase activity
heme-copper terminal oxidase activity
Process
mitochondrial electron transport, cytochrome c to oxygen
metabolic process
generation of precursor metabolites and energy
electron transport chain
respiratory electron transport chain
cellular metabolic process
Cellular Location
  1. Mitochondrion inner membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs MT-CO3
Gene Sequence
>784 bp
ATGACCCACCAATCACATGCCTATCATATAGTAAAACCCAGCCCATGACCCCTAACAGGG
GCCCTCTCAGCCCTCCTAATGACCTCCGGCCTAGCCATGTGATTTCACTTCCACTCCATA
ACGCTCCTCATACTAGGCCTACTAACCAACACACTAACCATATACCAATGATGGCGCGAT
GTAACACGAGAAAGCACATACCAAGGCCACCACACACCACCTGTCCAAAAAGGCCTTCGA
TACGGGATAATCCTATTTATTACCTCAGAAGTTTTTTTCTTCGCAGGATTTTTCTGAGCC
TTTTACCACTCCAGCCTAGCCCCTACCCCCCAATTAGGAGGGCACTGGCCCCCAACAGGC
ATCACCCCGCTAAATCCCCTAGAAGTCCCACTCCTAAACACATCCGTATTACTCGCATCA
GGAGTATCAATCACCTGAGCTCACCATAGTCTAATAGAAAACAACCGAAACCAAATAATT
CAAGCACTGCTTATTACAATTTTACTGGGTCTCTATTTTACCCTCCTACAAGCCTCAGAG
TACTTCGAGTCTCCCTTCACCATTTCCGACGGCATCTACGGCTCAACATTTTTTGTAGCC
ACAGGCTTCCACGGACTTCACGTCATTATTGGCTCAACTTTCCTCACTATCTGCTTCATC
CGCCAACTAATATTTCACTTTACATCCAAACATCACTTTGGCTTCGAAGCCGCCGCCTGA
TACTGGCATTTTGTAGATGTGGTTTGACTATTTCTGTATGTCTCCATCTATTGATGAGGG
TCTT
Protein Properties
Number of Residues 261
Molecular Weight 29950.6
Theoretical pI 7.34
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["15-35", "42-59", "81-101", "127-147", "159-179", "197-217", "239-259"]
Protein Sequence
>Cytochrome c oxidase subunit 3
MTHQSHAYHMVKPSPWPLTGALSALLMTSGLAMWFHFHSMTLLMLGLLTNTLTMYQWWRD
VTRESTYQGHHTPPVQKGLRYGMILFITSEVFFFAGFFWAFYHSSLAPTPQLGGHWPPTG
ITPLNPLEVPLLNTSVLLASGVSITWAHHSLMENNRNQMIQALLITILLGLYFTLLQASE
YFESPFTISDGIYGSTFFVATGFHGLHVIIGSTFLTICFIRQLMFHFTSKHHFGFEAAAW
YWHFVDVVWLFLYVSIYWWGS
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P00414
UniProtKB/Swiss-Prot Entry Name COX3_HUMAN
PDB IDs Not Available
GenBank Gene ID J01415
GeneCard ID MT-CO3
GenAtlas ID MT-CO3
HGNC ID HGNC:7422
References
General References Not Available