Identification |
HMDB Protein ID
| CDBP02486 |
Secondary Accession Numbers
| Not Available |
Name
| Beta-1,3-galactosyltransferase 5 |
Description
| Not Available |
Synonyms
|
- Beta-1,3-GalTase 5
- Beta-3-Gx-T5
- Beta3Gal-T5
- Beta3GalT5
- UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5
- UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5
- b3Gal-T5
|
Gene Name
| B3GALT5 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in galactosyltransferase activity |
Specific Function
| Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor |
GO Classification
|
Component |
membrane |
cell part |
Function |
galactosyltransferase activity |
catalytic activity |
transferase activity |
transferase activity, transferring hexosyl groups |
transferase activity, transferring glycosyl groups |
Process |
protein amino acid glycosylation |
metabolic process |
macromolecule metabolic process |
macromolecule modification |
protein modification process |
|
Cellular Location
|
- Golgi apparatus membrane
- Single-pass type II membrane protein (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 21q22.3 |
SNPs
| B3GALT5 |
Gene Sequence
|
>933 bp
ATGGCTTTCCCGAAGATGAGATTGATGTATATTTGCCTTCTGGTTCTGGGGGCTCTTTGT
TTGTATTTTAGCATGTACAGTCTAAATCCTTTCAAAGAACAGTCCTTTGTTTACAAGAAA
GACGGGAACTTCCTTAAGCTCCCAGATACAGACTGCAGGCAGACACCTCCCTTCCTCGTC
CTGCTGGTGACCTCATCCCACAAACAGTTGGCTGAGCGCATGGCCATCCGGCAGACGTGG
GGGAAAGAGAGGATGGTGAAGGGAAAGCAGCTGAAGACATTCTTCCTCCTGGGGACCACC
AGCAGTGCAGCGGAAACGAAAGAGGTGGACCAGGAGAGCCAGCGACACGGGGACATTATC
CAGAAGGATTTCCTAGACGTCTATTACAATCTGACCCTGAAGACCATGATGGGCATAGAA
TGGGTCCATCGCTTTTGTCCTCAGGCGGCGTTTGTGATGAAAACAGACTCAGACATGTTC
ATCAATGTTGACTATCTGACTGAACTGCTTCTGAAGAAAAACAGAACAACCAGGTTTTTC
ACTGGCTTCTTGAAACTCAATGAGTTTCCCATCAGGCAGCCATTCAGCAAGTGGTTTGTC
AGTAAATCTGAATATCCGTGGGACAGGTACCCACCATTCTGCTCCGGCACCGGCTACGTG
TTTTCTGGCGACGTGGCGAGTCAGGTGTACAATGTCTCCAAGAGCGTCCCATACATTAAA
CTGGAAGACGTGTTTGTGGGGCTCTGCCTCGAAAGGCTGAACATCAGATTGGAGGAGCTC
CACTCCCAGCCGACCTTTTTTCCAGGGGGCTTACGCTTCTCCGTATGCCTCTTCAGGAGG
ATCGTGGCCTGCCACTTCATCAAGCCTCGGACTCTCTTGGACTACTGGCAGGCTCTAGAG
AATTCCCGGGGGGAAGATTGTCCGCCTGTCTGA
|
Protein Properties |
Number of Residues
| 310 |
Molecular Weight
| 36188.9 |
Theoretical pI
| 9.02 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Beta-1,3-galactosyltransferase 5
MAFPKMRLMYICLLVLGALCLYFSMYSLNPFKEQSFVYKKDGNFLKLPDTDCRQTPPFLV
LLVTSSHKQLAERMAIRQTWGKERMVKGKQLKTFFLLGTTSSAAETKEVDQESQRHGDII
QKDFLDVYYNLTLKTMMGIEWVHRFCPQAAFVMKTDSDMFINVDYLTELLLKKNRTTRFF
TGFLKLNEFPIRQPFSKWFVSKSEYPWDRYPPFCSGTGYVFSGDVASQVYNVSKSVPYIK
LEDVFVGLCLERLNIRLEELHSQPTFFPGGLRFSVCLFRRIVACHFIKPRTLLDYWQALE
NSRGEDCPPV
|
External Links |
GenBank ID Protein
| 4835503 |
UniProtKB/Swiss-Prot ID
| Q9Y2C3 |
UniProtKB/Swiss-Prot Entry Name
| B3GT5_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB020337 |
GeneCard ID
| B3GALT5 |
GenAtlas ID
| B3GALT5 |
HGNC ID
| HGNC:920 |
References |
General References
| Not Available |