Identification |
HMDB Protein ID
| CDBP02472 |
Secondary Accession Numbers
| Not Available |
Name
| UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 |
Description
| Not Available |
Synonyms
|
- BGnT-7
- Beta-1,3-Gn-T7
- Beta-1,3-N-acetylglucosaminyltransferase 7
- Beta3Gn-T7
|
Gene Name
| B3GNT7 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in galactosyltransferase activity |
Specific Function
| May be involved in keratane sulfate biosynthesis. Transfers N-acetylgalactosamine on to keratan sulfate-related glycans. May play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues |
GO Classification
|
Component |
membrane |
cell part |
Function |
galactosyltransferase activity |
catalytic activity |
transferase activity |
transferase activity, transferring hexosyl groups |
transferase activity, transferring glycosyl groups |
Process |
protein modification process |
protein amino acid glycosylation |
metabolic process |
macromolecule metabolic process |
macromolecule modification |
|
Cellular Location
|
- Golgi apparatus membrane
- Single-pass type II membrane protein (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 2q37.1 |
SNPs
| B3GNT7 |
Gene Sequence
|
>1206 bp
ATGTCGCTGTGGAAGAAAACCGTCTACCGGAGTCTGTGCCTGGCCCTGGCCCTGCTCGTG
GCCGTGACGGTGTTCCAACGCAGTCTCACCCCTGGTCAGTTTCTGCAGGAGCCTCCGCCA
CCCACCCTGGAGCCACAGAAGGCCCAGAAGCCAAATGGACAGCTGGTGAACCCCAACAAC
TTCTGGAAGAACCCGAAAGATGTGGCTGCGCCCACGCCCATGGCCTCTCAGGGGCCCCAG
GCCTGGGACGTGACCACCACTAACTGCTCAGCCAATATCAACTTGACCCACCAGCCCTGG
TTCCAGGTCCTGGAGCCGCAGTTCCGGCAGTTTCTCTTCTACCGCCACTGCCGCTACTTC
CCCATGCTGCTGAACCACCCGGAGAAGTGCAGGGGCGATGTCTACCTGCTGGTGGTTGTC
AAGTCGGTCATCACGCAGCACGACCGCCGCGAGGCCATCCGCCAGACCTGGGGCCGCGAG
CGGCAGTCCGCGGGTGGGGGCCGAGGCGCCGTGCGCACCCTCTTCCTGCTGGGCACGGCC
TCCAAGCAGGAGGAGCGCACGCACTACCAGCAGCTGCTGGCCTACGAAGACCGCCTCTAC
GGCGACATCCTGCAGTGGGGCTTTCTCGACACCTTCTTCAACCTGACCCTCAAGGAGATC
CACTTCCTCAAGTGGCTGGACATCTACTGCCCCCACGTCCCCTTCATTTTCAAAGGCGAC
GATGACGTCTTCGTCAACCCCACCAACCTGCTAGAATTTCTGGCTGACCGGCAGCCACAG
GAAAACCTGTTCGTGGGCGATGTCCTGCAGCACGCTCGGCCCATTCGCAGGAAAGACAAC
AAATACTACATCCCGGGGGCCCTGTACGGCAAGGCCAGCTATCCGCCGTATGCAGGCGGC
GGTGGCTTCCTCATGGCCGGCAGCCTGGCCCGGCGCCTGCACCATGCCTGCGACACCCTG
GAGCTCTACCCGATCGACGACGTCTTTCTGGGCATGTGCCTGGAGGTGCTGGGCGTGCAG
CCCACGGCCCACGAGGGCTTCAAGACTTTCGGCATCTCCCGGAACCGCAACAGCCGCATG
AACAAGGAGCCGTGCTTTTTCCGCGCCATGCTCGTGGTGCACAAGCTGCTGCCCCCTGAG
CTGCTCGCCATGTGGGGGCTGGTGCACAGCAATCTCACCTGCTCCCGCAAGCTCCAGGTG
CTCTGA
|
Protein Properties |
Number of Residues
| 401 |
Molecular Weight
| 45986.9 |
Theoretical pI
| 9.29 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
MSLWKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNN
FWKNPKDVAAPTPMASQGPQAWDVTTTNCSANINLTHQPWFQVLEPQFRQFLFYRHCRYF
PMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTA
SKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGD
DDVFVNPTNLLEFLADRQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGG
GGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRNSRM
NKEPCFFRAMLVVHKLLPPELLAMWGLVHSNLTCSRKLQVL
|
External Links |
GenBank ID Protein
| 62988859 |
UniProtKB/Swiss-Prot ID
| Q8NFL0 |
UniProtKB/Swiss-Prot Entry Name
| B3GN7_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AC017104 |
GeneCard ID
| B3GNT7 |
GenAtlas ID
| B3GNT7 |
HGNC ID
| HGNC:18811 |
References |
General References
| Not Available |