Identification |
HMDB Protein ID
| CDBP02451 |
Secondary Accession Numbers
| Not Available |
Name
| Large neutral amino acids transporter small subunit 4 |
Description
| Not Available |
Synonyms
|
- L-type amino acid transporter 4
- Solute carrier family 43 member 2
|
Gene Name
| SLC43A2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in transmembrane transport |
Specific Function
| Sodium-, chloride, pH-independent high affinity transport of large neutral amino acids |
GO Classification
|
Process |
establishment of localization |
transport |
transmembrane transport |
|
Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 17p13.3 |
SNPs
| SLC43A2 |
Gene Sequence
|
>1710 bp
ATGGCGCCCACCCTGGCCACTGCCCATCGGCGCCGCTGGTGGATGGCCTGCACGGCCGTG
CTGGAGAACCTCCTCTTCTCGGCAGTCCTCCTGGGCTGGGGCTCGCTGCTCATCATGCTC
AAGTCAGAGGGCTTTTACTCCTACCTGTGTACCGAGCCAGAGAATGTCACCAATGGCACA
GTGGGCGGCACAGCAGAGCCGGGGCACGAGGAGGTGAGCTGGATGAACGGCTGGCTCAGC
TGCCAGGCCCAGGACGAGATGCTAAATTTGGCCTTCACTGTGGGCTCCTTTCTGCTCAGT
GCCATCACCCTGCCCCTGGGTATCGTCATGGACAAGTATGGCCCGAGGAAGCTCAGGCTG
CTGGGCAGCGCCTGCTTCGCGGTTTCCTGCTTGCTGATTGCGTACGGAGCAAGTAAACCA
AACGCTCTCTCCGTGCTCATCTTCATCGCCCTGGCTCTGAATGGCTTTGGTGGGATGTGT
ATGACCTTCACCTCATTAACACTGCCCAACATGTTCGGCGACCTTCGGTCCACGTTTATT
GCCTTGATGATTGGGTCCTACGCCTCCTCGGCAGTCACCTTTCCAGGAATCAAGCTCATC
TATGATGCTGGTGTCTCCTTCATCGTCGTCCTCGTGGTCTGGGCCGGCTGCTCCGGGCTG
GTTTTCCTCAACTGCTTCTTTAACTGGCCCCTTGAGCCCTTCCCGGGGCCGGAGGACATG
GACTACTCGGTGAAGATCAAGTTCAGCTGGCTGGGCTTTGACCACAAGATCACAGGGAAG
CAGTTCTACAAGCAGGTGACCACGGTGGGCCGGCGCCTGAGTGTGGGCAGCTCCATGAGG
AGTGCCAAGGAGCAGGTGGCGCTGCAGGAGGGCCACAAGCTGTGCCTGTCCACCGTCGAC
CTGGAGGTGAAGTGCCAGCCGGATGCCGCAGTGGCCCCCTCCTTCATGCACAGCGTGTTC
AGCCCCATCCTGCTGCTCAGCCTGGTCACCATGTGCGTCACGCAGCTGCGGCTCATCTTC
TACATGGGGGCTATGAACAACATCCTCAAGTTCCTGGTCAGCGGCGACCAGAAGACAGTT
GGCCTCTACACCTCCATCTTCGGCGTGCTCCAGCTGCTGTGCCTGCTGACGGCCCCCGTC
ATTGGCTACATCATGGACTGGAGGCTGAAGGAGTGTGAAGACGCCTCCGAGGAGCCCGAG
GAGAAAGACGCCAACCAAGGCGAGAAGAAAAAGAAGAAGCGGGACCGGCAGATCCAGAAG
ATCACTAATGCCATGCGGGCCTTCGCCTTCACCAACCTGCTGCTCGTGGGCTTTGGGGTG
ACCTGCCTCATTCCCAACCTGCCTCTCCAGATCCTCTCCTTCATCCTGCACACAATCGTG
CGAGGATTCATCCACTCCGCTGTCGGGGGCCTGTACGCTGCCGTGTACCCCTCCACCCAG
TTCGGCAGCCTCACGGGACTGCAGTCTCTGATCAGCGCGCTCTTCGCCCTTCTGCAGCAG
CCGCTGTTTCTGGCCATGATGGGTCCTCTCCAGGGAGACCCTCTGTGGGTGAACGTGGGG
CTGCTCCTTCTCAGCCTGCTGGGCTTCTGCCTCCCGCTCTACCTGATCTGCTACCGGCGC
CAGCTGGAGCGGCAGCTGCAGCAGAGGCAGGAGGATGACAAACTCTTCCTCAAAATCAAC
GGCTCGTCCAACCAGGAGGCCTTCGTGTAG
|
Protein Properties |
Number of Residues
| 569 |
Molecular Weight
| 62746.3 |
Theoretical pI
| 8.0 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
- ["20-40", "90-110", "120-140", "143-163", "177-197", "203-223", "323-345", "365-385", "435-455", "462-482", "490-510", "516-536"]
|
Protein Sequence
|
>Large neutral amino acids transporter small subunit 4
MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTEPENVTNGT
VGGTAEPGHEEVSWMNGWLSCQAQDEMLNLAFTVGSFLLSAITLPLGIVMDKYGPRKLRL
LGSACFAVSCLLIAYGASKPNALSVLIFIALALNGFGGMCMTFTSLTLPNMFGDLRSTFI
ALMIGSYASSAVTFPGIKLIYDAGVSFIVVLVVWAGCSGLVFLNCFFNWPLEPFPGPEDM
DYSVKIKFSWLGFDHKITGKQFYKQVTTVGRRLSVGSSMRSAKEQVALQEGHKLCLSTVD
LEVKCQPDAAVAPSFMHSVFSPILLLSLVTMCVTQLRLIFYMGAMNNILKFLVSGDQKTV
GLYTSIFGVLQLLCLLTAPVIGYIMDWRLKECEDASEEPEEKDANQGEKKKKKRDRQIQK
ITNAMRAFAFTNLLLVGFGVTCLIPNLPLQILSFILHTIVRGFIHSAVGGLYAAVYPSTQ
FGSLTGLQSLISALFALLQQPLFLAMMGPLQGDPLWVNVGLLLLSLLGFCLPLYLICYRR
QLERQLQQRQEDDKLFLKINGSSNQEAFV
|
External Links |
GenBank ID Protein
| 22748751 |
UniProtKB/Swiss-Prot ID
| Q8N370 |
UniProtKB/Swiss-Prot Entry Name
| LAT4_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_152346.1 |
GeneCard ID
| SLC43A2 |
GenAtlas ID
| SLC43A2 |
HGNC ID
| HGNC:23087 |
References |
General References
| Not Available |