Identification
HMDB Protein ID CDBP02435
Secondary Accession Numbers Not Available
Name Solute carrier family 26 member 9
Description Not Available
Synonyms
  1. Anion transporter/exchanger protein 9
Gene Name SLC26A9
Protein Type Transporter
Biological Properties
General Function Involved in secondary active sulfate transmembrane transporter activity
Specific Function DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Mediates chloride/bicarbonate exchange or chloride-independent bicarbonate extrusion thus assuring bicarbonate secretion. Inhibited by ammonium and thiosulfate
GO Classification
Component
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
inorganic anion transmembrane transporter activity
sulfate transmembrane transporter activity
secondary active sulfate transmembrane transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
transporter activity
anion transmembrane transporter activity
Process
transport
transmembrane transport
anion transport
inorganic anion transport
sulfate transport
ion transport
establishment of localization
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1q32.1
SNPs SLC26A9
Gene Sequence
>2376 bp
ATGAGCCAGCCCAGGCCCCGCTACGTGGTAGACAGAGCCGCATACTCCCTTACCCTCTTC
GACGATGAGTTTGAGAAGAAGGACCGGACATACCCAGTGGGAGAGAAACTTCGCAATGCC
TTCAGATGTTCCTCAGCCAAGATCAAAGCTGTGGTGTTTGGGCTGCTGCCTGTGCTCTCC
TGGCTCCCCAAGTACAAGATTAAAGACTACATCATTCCTGACCTGCTCGGTGGACTCAGC
GGGGGATCCATCCAGGTCCCACAAGGCATGGCATTTGCTCTGCTGGCCAACCTTCCTGCA
GTCAATGGCCTCTACTCCTCCTTCTTCCCCCTCCTGACCTACTTCTTCCTGGGGGGTGTT
CACCAGATGGTGCCAGGTACCTTTGCCGTTATCAGCATCCTGGTGGGTAACATCTGTCTG
CAGCTGGCCCCAGAGTCGAAATTCCAGGTCTTCAACAATGCCACCAATGAGAGCTATGTG
GACACAGCAGCCATGGAGGCTGAGAGGCTGCACGTGTCAGCTACGCTAGCCTGCCTCACC
GCCATCATCCAGATGGGTCTGGGCTTCATGCAGTTTGGCTTTGTGGCCATCTACCTCTCC
GAGTCCTTCATCCGGGGCTTCATGACGGCCGCCGGCCTGCAGATCCTGATTTCGGTGCTC
AAGTACATCTTCGGACTGACCATCCCCTCCTACACAGGCCCAGGGTCCATCGTCTTTACC
TTCATTGACATTTGCAAAAACCTCCCCCACACCAACATCGCCTCGCTCATCTTCGCTCTC
ATCAGCGGTGCCTTCCTGGTGCTGGTGAAGGAGCTCAATGCTCGCTACATGCACAAGATT
CGCTTCCCCATCCCTACAGAGATGATTGTGGTGGTGGTGGCAACAGCTATCTCCGGGGGC
TGTAAGATGCCCAAAAAGTATCACATGCAGATCGTGGGAGAAATCCAACGCGGGTTCCCC
ACCCCGGTGTCGCCTGTGGTCTCACAGTGGAAGGACATGATAGGCACAGCCTTCTCCCTA
GCCATCGTGAGCTACGTCATCAACCTGGCTATGGGCCGGACCCTGGCCAACAAGCACGGC
TACGACGTGGATTCGAACCAGGAGATGATCGCTCTCGGCTGCAGCAACTTCTTTGGCTCC
TTCTTTAAAATTCATGTCATTTGCTGTGCGCTTTCTGTCACTCTGGCTGTGGATGGAGCT
GGAGGAAAATCCCAGGTGGCCAGCCTGTGTGTGTCTCTGGTGGTGATGATCACCATGCTG
GTCCTGGGGATCTATCTGTATCCTCTCCCTAAGTCTGTGCTAGGAGCCCTGATCGCTGTC
AATCTCAAGAACTCCCTCAAGCAACTCACCGACCCCTACTACCTGTGGAGGAAGAGCAAG
CTGGACTGTTGCATCTGGGTAGTGAGCTTCCTCTCCTCCTTCTTCCTCAGCCTGCCCTAT
GGTGTGGCAGTGGGTGTCGCCTTCTCCGTCCTGGTCGTGGTCTTCCAGACTCAGTTTCGA
AATGGCTATGCACTGGCCCAGGTCATGGACACTGACATTTATGTGAATCCCAAGACCTAT
AATAGGGCCCAGGATATCCAGGGGATTAAAATCATCACGTACTGCTCCCCTCTCTACTTT
GCCAACTCAGAGATCTTCAGGCAAAAGGTCATCGCCAAGACAGGCATGGACCCCCAGAAA
GTATTACTAGCCAAGCAAAAATACCTCAAGAAGCAGGAGAAGCGGAGAATGAGGCCCACA
CAACAGAGGAGGTCTCTATTCATGAAAACCAAGACTGTCTCCCTGCAGGAGCTGCAGCAG
GACTTTGAGAATGCGCCCCCCACCGACCCCAACAACAACCAGACCCCGGCTAACGGCACC
AGCGTGTCCTATATCACCTTCAGCCCTGACAGCTCCTCACCTGCCCAGAGTGAGCCACCA
GCCTCCGCTGAGGCCCCCGGCGAGCCCAGTGACATGCTGGCCAGCGTCCCACCCTTCGTC
ACCTTCCACACCCTCATCCTGGACATGAGTGGAGTCAGCTTCGTGGACTTGATGGGCATC
AAGGCCCTGGCCAAGCTGAGCTCCACCTATGGGAAGATCGGCGTGAAGGTCTTCTTGGTG
AACATCCATGCCCAGGTGTACAATGACATTAGCCATGGAGGCGTCTTTGAGGATGGGAGT
CTAGAATGCAAGCACGTCTTTCCCAGCATACATGACGCAGTCCTCTTTGCCCAGGCAAAT
GCTAGAGACGTGACCCCAGGACACAACTTCCAAGGGGCTCCAGGGGATGCTGAGCTCTCC
TTGTACGACTCAGAGGAGGACATTCGCAGCTACTGGGACTTAGAGCAGGAGATGTTCGGG
AGCATGTTTCACGCAGAGACCCTGACCGCCCTGTGA
Protein Properties
Number of Residues 791
Molecular Weight 86987.5
Theoretical pI 8.32
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["43-63", "71-91", "92-112", "115-135", "179-199", "200-220", "222-242", "249-269", "280-300", "332-352", "377-397", "406-426", "474-494"]
Protein Sequence
>Solute carrier family 26 member 9
MSQPRPRYVVDRAAYSLTLFDDEFEKKDRTYPVGEKLRNAFRCSSAKIKAVVFGLLPVLS
WLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGV
HQMVPGTFAVISILVGNICLQLAPESKFQVFNNATNESYVDTAAMEAERLHVSATLACLT
AIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFT
FIDICKNLPHTNIASLIFALISGAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAISGG
CKMPKKYHMQIVGEIQRGFPTPVSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHG
YDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITML
VLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSLPY
GVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPLYF
ANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQ
DFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPPFV
TFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGS
LECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDIRSYWDLEQEMFG
SMFHAETLTAL
GenBank ID Protein 15341556
UniProtKB/Swiss-Prot ID Q7LBE3
UniProtKB/Swiss-Prot Entry Name S26A9_HUMAN
PDB IDs Not Available
GenBank Gene ID AF331525
GeneCard ID SLC26A9
GenAtlas ID SLC26A9
HGNC ID HGNC:14469
References
General References Not Available