2412 CDBP02411 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 P14060 3BHS1_HUMAN true false Enzyme Homo_sapiens HSD3B1 373 42251.25 8.712 Involved in 3-beta-hydroxy-delta5-steroid dehydrogenase activity 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone. M27137 HSD3B1 1 1p13.1 HSD3B1 HGNC:5217 true hsa:3283 HS08829-MONOMER NP_000853.1:NM_000862.2 Placenta and skin. Predominantly expressed in mammary gland tissue. 2020-06-12T23:07:04Z 2020-07-28T02:27:49Z 0 0 0