Identification |
HMDB Protein ID
| CDBP02406 |
Secondary Accession Numbers
| Not Available |
Name
| DBH-like monooxygenase protein 1 |
Description
| Not Available |
Synonyms
|
- Monooxygenase X
|
Gene Name
| MOXD1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in monooxygenase activity |
Specific Function
| Not Available |
GO Classification
|
Function |
metal ion binding |
binding |
catalytic activity |
transition metal ion binding |
monooxygenase activity |
oxidoreductase activity |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen |
copper ion binding |
dopamine beta-monooxygenase activity |
ion binding |
cation binding |
Process |
cellular amino acid metabolic process |
catecholamine metabolic process |
histidine family amino acid metabolic process |
histidine metabolic process |
histidine catabolic process |
metabolic process |
cellular process |
cellular metabolic process |
oxidation reduction |
cellular amino acid derivative metabolic process |
cellular biogenic amine metabolic process |
cellular amino acid and derivative metabolic process |
|
Cellular Location
|
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:6 |
Locus
| 6q23.2 |
SNPs
| MOXD1 |
Gene Sequence
|
>1842 bp
ATGTGCTGCTGGCCGCTGCTCCTGCTGTGGGGGCTGCTCCCCGGGACGGCGGCGGGGGGC
TCGGGCCGAACCTATCCGCACCGGACCCTCCTGGACTCGGAGGGCAAGTACTGGCTGGGC
TGGAGCCAGCGGGGCAGCCAGATCGCCTTCCGCCTCCAGGTGCGCACTGCAGGCTACGTG
GGCTTCGGCTTCTCGCCCACCGGGGCCATGGCGTCCGCCGACATCGTCGTGGGCGGGGTG
GCCCACGGGCGGCCCTACCTCCAGGATTATTTTACAAATGCAAATAGAGAGTTGAAAAAA
GATGCTCAGCAAGATTACCATCTAGAATATGCCATGGAAAATAGCACACACACAATAATT
GAATTTACCAGAGAGCTGCATACATGTGACATAAATGACAAGAGTATAACGGATAGCACT
GTGAGAGTGATCTGGGCCTACCACCATGAAGATGCAGGAGAAGCTGGTCCCAAGTACCAT
GACTCCAATAGGGGCACCAAGAGTTTGCGGTTATTGAATCCTGAGAAAACTAGTGTGCTA
TCTACAGCCTTACCATACTTTGATCTGGTAAATCAGGACGTCCCCATCCCAAACAAAGAT
ACAACATATTGGTGCCAAATGTTTAAGATTCCTGTGTTCCAAGAAAAGCATCATGTAATA
AAGGTTGAGCCAGTGATACAGAGAGGCCATGAGAGTCTGGTGCACCACATCCTGCTCTAT
CAGTGCAGCAACAACTTTAACGACAGCGTTCTGGAGTCCGGCCACGAGTGCTATCACCCC
AACATGCCCGATGCATTCCTCACCTGTGAAACTGTGATTTTTGCCTGGGCTATTGGTGGA
GAGGGCTTTTCTTATCCACCTCATGTTGGATTATCCCTTGGCACTCCATTAGATCCGCAT
TATGTGCTCCTAGAAGTCCATTATGATAATCCCACTTATGAGGAAGGCTTAATAGATAAT
TCTGGACTGAGGTTATTTTACACAATGGATATAAGGAAATATGATGCTGGGGTGATTGAG
GCTGGCCTCTGGGTGAGCCTCTTCCATACCATCCCTCCAGGGATGCCTGAGTTCCAGTCT
GAGGGTCACTGCACTTTGGAGTGCCTGGAAGAGGCTCTGGAAGCCGAAAAGCCAAGTGGA
ATTCATGTGTTTGCTGTTCTTCTCCATGCTCACCTGGCTGGCAGAGGCATCAGGCTGCGT
CATTTTCGAAAAGGGAAGGAAATGAAATTACTTGCCTATGATGATGATTTTGACTTCAAT
TTCCAGGAGTTTCAGTATCTAAAGGAAGAACAAACAATCTTACCAGGAGATAACCTAATT
ACTGAGTGTCGCTACAACACGAAAGATAGAGCTGAGATGACTTGGGGAGGACTAAGCACC
AGGAGTGAAATGTGTCTCTCATACCTTCTTTATTACCCAAGAATTAATCTTACTCGATGT
GCAAGTATTCCAGACATTATGGAACAACTTCAGTTCATTGGGGTTAAGGAGATCTACAGA
CCAGTCACGACCTGGCCTTTCATTATCAAAAGTCCCAAGCAATATAAAAACCTTTCTTTC
ATGGATGCTATGAATAAGTTTAAATGGACTAAAAAGGAAGGTCTCTCCTTCAACAAGCTG
GTCCTCAGCCTGCCAGTGAATGTGAGATGTTCCAAGACAGACAATGCTGAGTGGTCGATT
CAAGGAATGACAGCATTACCTCCAGATATAGAAAGACCCTATAAAGCAGAACCTTTGGTG
TGTGGCACGTCTTCTTCCTCTTCCCTGCACAGAGATTTCTCCATCAACTTGCTTGTTTGC
CTTCTGCTACTCAGCTGCACGCTGAGCACCAAGAGCTTGTGA
|
Protein Properties |
Number of Residues
| 613 |
Molecular Weight
| 69651.9 |
Theoretical pI
| 6.41 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>DBH-like monooxygenase protein 1
MCCWPLLLLWGLLPGTAAGGSGRTYPHRTLLDSEGKYWLGWSQRGSQIAFRLQVRTAGYV
GFGFSPTGAMASADIVVGGVAHGRPYLQDYFTNANRELKKDAQQDYHLEYAMENSTHTII
EFTRELHTCDINDKSITDSTVRVIWAYHHEDAGEAGPKYHDSNRGTKSLRLLNPEKTSVL
STALPYFDLVNQDVPIPNKDTTYWCQMFKIPVFQEKHHVIKVEPVIQRGHESLVHHILLY
QCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLDPH
YVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEFQS
EGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAGRGIRLRHFRKGKEMKLLAYDDDFDFN
FQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEMCLSYLLYYPRINLTRC
ASIPDIMEQLQFIGVKEIYRPVTTWPFIIKSPKQYKNLSFMDAMNKFKWTKKEGLSFNKL
VLSLPVNVRCSKTDNAEWSIQGMTALPPDIERPYKAEPLVCGTSSSSSLHRDFSINLLVC
LLLLSCTLSTKSL
|
External Links |
GenBank ID Protein
| 118421087 |
UniProtKB/Swiss-Prot ID
| Q6UVY6 |
UniProtKB/Swiss-Prot Entry Name
| MOXD1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_015529.2 |
GeneCard ID
| MOXD1 |
GenAtlas ID
| MOXD1 |
HGNC ID
| HGNC:21063 |
References |
General References
| Not Available |