Identification |
HMDB Protein ID
| CDBP02398 |
Secondary Accession Numbers
| Not Available |
Name
| Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma |
Description
| Not Available |
Synonyms
|
- PI(5)P 4-kinase type II gamma
- PIP4KII-gamma
- Phosphatidylinositol-5-phosphate 4-kinase type II gamma
|
Gene Name
| PIP4K2C |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in phosphatidylinositol phosphate kinase activity |
Specific Function
| May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum |
GO Classification
|
Function |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
phosphatidylinositol phosphate kinase activity |
lipid kinase activity |
Process |
metabolic process |
phosphatidylinositol metabolic process |
organophosphate metabolic process |
phospholipid metabolic process |
glycerophospholipid metabolic process |
phosphoinositide metabolic process |
|
Cellular Location
|
- Cytoplasm
- Membrane
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 12q13.3 |
SNPs
| PIP4K2C |
Gene Sequence
|
>1266 bp
ATGGCGTCCTCCTCGGTCCCACCAGCCACGGTATCGGCGGCGACAGCAGGCCCCGGCCCA
GGTTTCGGCTTCGCCTCCAAGACCAAGAAGAAGCATTTCGTGCAGCAGAAGGTGAAGGTG
TTCCGGGCGGCCGACCCGCTGGTGGGTGTGTTCCTGTGGGGCGTAGCCCACTCGATCAAT
GAGCTCAGCCAGGTGCCTCCCCCGGTGATGCTGCTGCCAGATGACTTTAAGGCCAGCTCC
AAGATCAAGGTCAACAATCACCTTTTCCACAGGGAAAATCTGCCCAGTCATTTCAAGTTC
AAGGAGTATTGTCCCCAGGTCTTCAGGAACCTCCGTGATCGATTTGGCATTGATGACCAA
GATTACTTGGTGTCCCTTACCCGAAACCCCCCCAGCGAAAGTGAAGGCAGTGATGGTCGC
TTCCTTATCTCCTACGATCGGACTCTGGTCATCAAAGAAGTATCCAGTGAGGACATTGCT
GACATGCATAGCAACCTCTCCAACTATCACCAGTACATTGTGAAGTGCCATGGCAACACG
CTTCTGCCCCAGTTCCTGGGGATGTACCGAGTCAGTGTGGACAACGAAGACAGCTACATG
CTTGTGATGCGCAATATGTTTAGCCACCGTCTTCCTGTGCACAGGAAGTATGACCTCAAG
GGTTCCCTAGTGTCCCGGGAAGCCAGCGATAAGGAAAAGGTTAAAGAATTGCCCACCCTT
AAGGATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAA
ATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGAC
TACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCG
CCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCT
CTGGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGG
CCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAA
GGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGAT
GCCAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATC
TCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTT
GCCTAA
|
Protein Properties |
Number of Residues
| 421 |
Molecular Weight
| 47285.5 |
Theoretical pI
| 6.84 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEG
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
A
|
External Links |
GenBank ID Protein
| 226371739 |
UniProtKB/Swiss-Prot ID
| Q8TBX8 |
UniProtKB/Swiss-Prot Entry Name
| PI42C_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_001146258.1 |
GeneCard ID
| PIP4K2C |
GenAtlas ID
| PIP4K2C |
HGNC ID
| HGNC:23786 |
References |
General References
| Not Available |