Identification |
HMDB Protein ID
| CDBP02392 |
Secondary Accession Numbers
| Not Available |
Name
| V-type proton ATPase subunit D |
Description
| Not Available |
Synonyms
|
- V-ATPase 28 kDa accessory protein
- V-ATPase subunit D
- Vacuolar proton pump subunit D
|
Gene Name
| ATP6V1D |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in ATPase activity, coupled to transmembrane movement of substances |
Specific Function
| Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system |
GO Classification
|
Component |
proton-transporting two-sector atpase complex, catalytic domain |
macromolecular complex |
protein complex |
Function |
cation transmembrane transporter activity |
inorganic cation transmembrane transporter activity |
monovalent inorganic cation transmembrane transporter activity |
hydrogen ion transmembrane transporter activity |
transporter activity |
active transmembrane transporter activity |
primary active transmembrane transporter activity |
p-p-bond-hydrolysis-driven transmembrane transporter activity |
atpase activity, coupled to transmembrane movement of substances |
proton-transporting atpase activity, rotational mechanism |
transmembrane transporter activity |
substrate-specific transmembrane transporter activity |
ion transmembrane transporter activity |
Process |
atp synthesis coupled proton transport |
atp biosynthetic process |
purine nucleotide metabolic process |
purine nucleotide biosynthetic process |
purine nucleoside triphosphate biosynthetic process |
purine ribonucleoside triphosphate biosynthetic process |
metabolic process |
nitrogen compound metabolic process |
cellular nitrogen compound metabolic process |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
nucleobase, nucleoside and nucleotide metabolic process |
nucleoside phosphate metabolic process |
nucleotide metabolic process |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 14q23-q24.2 |
SNPs
| ATP6V1D |
Gene Sequence
|
>744 bp
ATGTCGGGCAAAGACCGAATTGAAATCTTTCCCTCGCGAATGGCACAGACCATCATGAAG
GCTCGTTTAAAGGGAGCACAGACAGGTCGAAACCTCCTGAAGAAAAAATCTGATGCCTTA
ACTCTTCGATTTCGACAGATCCTAAAGAAGATAATAGAGACTAAAATGTTGATGGGCGAA
GTGATGAGAGAAGCTGCCTTTTCACTAGCTGAAGCCAAGTTCACAGCAGGTGACTTCAGC
ACTACAGTTATCCAAAATGTCAATAAAGCGCAAGTGAAGATTCGAGCGAAGAAAGATAAT
GTAGCAGGTGTTACTTTGCCAGTATTTGAACATTACCATGAAGGAACTGACAGTTATGAA
CTGACTGGTTTAGCCAGAGGTGGGGAACAGTTGGCTAAATTAAAGAGGAATTATGCCAAA
GCAGTGGAACTACTGGTGGAACTAGCTTCTCTGCAGACTTCTTTTGTTACTTTGGATGAA
GCTATTAAGATAACCAACAGGCGTGTAAATGCCATTGAACATGTCATCATTCCCCGGATT
GAACGTACTCTTGCTTATATCATCACAGAGCTGGATGAGAGAGAGCGAGAAGAGTTCTAT
AGGTTAAAGAAAATACAAGAGAAGAAAAAGATTCTAAAGGAAAAATCTGAGAAGGACTTG
GAGCAAAGGAGAGCAGCTGGAAGGTGTTGGAGCCTGCTAATCTTCTTGGCTGAAGAGAAG
GACGAGGATCTTCTATTTGAATAA
|
Protein Properties |
Number of Residues
| 247 |
Molecular Weight
| 28262.5 |
Theoretical pI
| 10.01 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>V-type proton ATPase subunit D
MSGKDRIEIFPSRMAQTIMKARLKGAQTGRNLLKKKSDALTLRFRQILKKIIETKMLMGE
VMREAAFSLAEAKFTAGDFSTTVIQNVNKAQVKIRAKKDNVAGVTLPVFEHYHEGTDSYE
LTGLARGGEQLAKLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPRI
ERTLAYIITELDEREREEFYRLKKIQEKKKILKEKSEKDLEQRRAAGEVLEPANLLAEEK
DEDLLFE
|
External Links |
GenBank ID Protein
| 5138993 |
UniProtKB/Swiss-Prot ID
| Q9Y5K8 |
UniProtKB/Swiss-Prot Entry Name
| VATD_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF100741 |
GeneCard ID
| ATP6V1D |
GenAtlas ID
| ATP6V1D |
HGNC ID
| HGNC:13527 |
References |
General References
| Not Available |