| Identification |
|---|
| HMDB Protein ID
| CDBP02379 |
| Secondary Accession Numbers
| Not Available |
| Name
| ADP/ATP translocase 3 |
| Description
| Not Available |
| Synonyms
|
- ADP,ATP carrier protein 3
- ADP,ATP carrier protein, isoform T2
- ANT 2
- ANT 3
- Adenine nucleotide translocator 3
- Solute carrier family 25 member 6
|
| Gene Name
| SLC25A6 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in transporter activity |
| Specific Function
| Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis |
| GO Classification
|
| Component |
| membrane |
| cell part |
| organelle membrane |
| organelle inner membrane |
| mitochondrial inner membrane |
| Function |
| binding |
| transporter activity |
| Process |
| establishment of localization |
| transport |
| transmembrane transport |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| SLC25A6 |
| Gene Sequence
|
>897 bp
ATGACGGAACAGGCCATCTCCTTCGCCAAAGACTTCTTGGCCGGAGGCATCGCCGCCGCC
ATCTCCAAGACGGCCGTGGCTCCGATCGAGCGGGTCAAGCTGCTGCTGCAGGTCCAGCAC
GCCAGCAAGCAGATCGCCGCCGACAAGCAGTACAAGGGCATCGTGGACTGCATTGTCCGC
ATCCCCAAGGAGCAGGGCGTGCTGTCCTTCTGGAGGGGCAACCTTGCCAACGTCATTCGC
TACTTCCCCACTCAAGCCCTCAACTTCGCCTTCAAGGATAAGTACAAGCAGATCTTCCTG
GGGGGCGTGGACAAGCACACGCAGTTCTGGAGGTACTTTGCGGGCAACCTGGCCTCCGGC
GGTGCGGCCGGCGCGACCTCCCTCTGCTTCGTGTACCCGCTGGATTTCGCCAGAACCCGC
CTGGCAGCGGACGTGGGAAAGTCAGGCACAGAGCGCGAGTTCCGAGGCCTGGGAGACTGC
CTGGTGAAGATCACCAAGTCCGACGGCATCCGGGGCCTGTACCAGGGCTTCAGTGTCTCC
GTGCAGGGCATCATCATCTACCGGGCGGCCTACTTCGGCGTGTACGATACGGCCAAGGGC
ATGCTCCCCGACCCCAAGAACACGCACATCGTGGTGAGCTGGATGATCGCGCAGACCGTG
ACGGCCGTGGCCGGCGTGGTGTCCTACCCCTTCGACACGGTGCGGCGGCGCATGATGATG
CAGTCCGGGCGCAAAGGAGCTGACATCATGTACACGGGCACCGTCGACTGTTGGAGGAAG
ATCTTCAGAGATGAGGGGGGCAAGGCCTTCTTCAAGGGTGCGTGGTCCAACGTCCTGCGG
GGCATGGGGGGCGCCTTCGTGCTGGTCCTGTACGACGAGCTCAAGAAGGTGATCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 298 |
| Molecular Weight
| 32866.0 |
| Theoretical pI
| 10.26 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["5-39", "75-100", "109-143", "176-202", "207-241", "273-298"]
|
| Protein Sequence
|
>ADP/ATP translocase 3
MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVR
IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASG
GAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVS
VQGIIIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMM
QSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P12236 |
| UniProtKB/Swiss-Prot Entry Name
| ADT3_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AY007135 |
| GeneCard ID
| SLC25A6 |
| GenAtlas ID
| SLC25A6 |
| HGNC ID
| HGNC:10992 |
| References |
|---|
| General References
| Not Available |