Cannabis Compound Database: Showing Protein Phosphoglucomutase-2 (CDBP02365)

Identification Biological properties Gene properties Protein properties External links References XML Show 6 compounds

Identification

HMDB Protein ID

CDBP02365

Secondary Accession Numbers

Not Available

Name

Phosphoglucomutase-2

Description

Not Available

Synonyms

Glucose phosphomutase 2
PGM 2
Phosphodeoxyribomutase
Phosphopentomutase

Gene Name

PGM2

Protein Type

Enzyme

Biological Properties

General Function

Involved in intramolecular transferase activity, phosphotransferases

Specific Function

Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity.

GO Classification

Biological Process
small molecule metabolic process
glucose metabolic process
deoxyribose phosphate catabolic process
glycogen catabolic process
glycogen biosynthetic process
Cellular Component
cytosol
Function
magnesium ion binding
isomerase activity
intramolecular transferase activity
intramolecular transferase activity, phosphotransferases
ion binding
cation binding
metal ion binding
binding
catalytic activity
Molecular Function
phosphoglucomutase activity
phosphopentomutase activity
magnesium ion binding
Process
metabolic process
primary metabolic process
carbohydrate metabolic process

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
2-deoxy-D-ribose 1-phosphate degradation	Not Available	Not Available
Glycolysis / Gluconeogenesis	Not Available
Amino sugar and nucleotide sugar metabolism	Not Available

Gene Properties

Chromosome Location

Locus

4p14

SNPs

PGM2

Gene Sequence

>1839 bp
ATGGCGGCTCCAGAAGGCAGCGGTCTAGGCGAGGACGCCCGGCTGGACCAGGAGACCGCC
CAGTGGCTGCGCTGGGACAAGAATTCCTTAACTTTGGAGGCAGTGAAACGACTAATAGCA
GAAGGTAATAAAGAAGAACTACGAAAATGTTTTGGGGCCCGAATGGAGTTTGGGACAGCT
GGCCTCCGAGCTGCTATGGGACCTGGAATTTCTCGTATGAATGACTTGACCATCATCCAG
ACTACACAGGGATTTTGCAGATACCTGGAAAAACAATTCAGTGACTTAAAGCAGAAAGGC
ATCGTGATCAGTTTTGACGCCCGAGCTCATCCATCCAGTGGGGGTAGCAGCAGAAGGTTT
GCCCGACTTGCTGCAACCACATTTATCAGTCAGGGGATTCCTGTGTACCTCTTTTCTGAT
ATAACGCCAACCCCCTTTGTGCCCTTCACAGTATCACATTTGAAACTTTGTGCTGGAATC
ATGATAACTGCATCTCACAATCCAAAGCAGGATAATGGTTATAAGGTCTATTGGGATAAT
GGAGCTCAGATCATTTCTCCTCACGATAAAGGGATTTCTCAAGCTATTGAAGAAAATCTA
GAACCGTGGCCTCAAGCTTGGGACGATTCTTTAATTGATAGCAGTCCACTTCTCCACAAT
CCGAGTGCTTCCATCAATAATGACTACTTTGAAGACCTTAAAAAGTACTGTTTCCACAGG
AGCGTGAACAGGGAGACAAAGGTGAAGTTTGTGCACACCTCTGTCCATGGGGTGGGTCAT
AGCTTTGTGCAGTCAGCTTTCAAGGCTTTTGACCTTGTTCCTCCTGAGGCTGTTCCTGAA
CAGAAAGATCCGGATCCTGAGTTTCCAACAGTGAAATACCCGAATCCCGAAGAGGGGAAA
GGTGTCTTGACTTTGTCTTTTGCTTTGGCTGACAAAACCAAGGCCAGAATTGTTTTAGCT
AACGACCCGGATGCTGATAGACTTGCTGTGGCAGAAAAGCAAGACAGTGGTGAATGGAGG
GTGTTTTCAGGCAATGAGTTGGGGGCCCTCCTGGGCTGGTGGCTTTTTACATCTTGGAAA
GAGAAGAACCAGGATCGCAGTGCTCTCAAAGACACGTACATGTTGTCCAGCACCGTCTCC
TCCAAAATCTTGCGGGCCATTGCCTTAAAGGAAGGTTTTCATTTTGAGGAAACATTAACT
GGCTTTAAGTGGATGGGAAACAGAGCCAAACAGCTAATAGACCAGGGGAAAACTGTTTTA
TTTGCATTTGAAGAAGCTATTGGATACATGTGCTGCCCTTTTGTTCTGGACAAAGATGGA
GTCAGTGCCGCTGTCATAAGTGCAGAGTTGGCTAGCTTCCTAGCAACCAAGAATTTGTCT
TTGTCTCAGCAACTAAAGGCCATTTATGTGGAGTATGGCTACCATATTACTAAAGCTTCC
TATTTTATCTGCCATGATCAAGAAACCATTAAGAAATTATTTGAAAACCTCAGAAACTAC
GATGGAAAAAATAATTATCCAAAAGCTTGTGGCAAATTTGAAATTTCTGCCATTAGGGAC
CTTACAACTGGCTATGATGATAGCCAACCTGATAAAAAAGCTGTTCTTCCCACTAGTAAA
AGCAGCCAAATGATCACCTTCACCTTTGCTAATGGAGGCGTGGCCACCATGCGCACCAGT
GGGACAGAGCCCAAAATCAAGTACTATGCAGAGCTGTGTGCCCCACCTGGGAACAGTGAT
CCTGAGCAGCTGAAGAAGGAACTGAATGAACTGGTCAGTGCTATTGAAGAACATTTTTTC
CAGCCACAGAAGTACAATCTGCAGCCAAAAGCAGACTAA

Protein Properties

Number of Residues

612

Molecular Weight

68282.765

Theoretical pI

6.722

Pfam Domain Function

PGM_PMM_I (PF02878 )
PGM_PMM_II (PF02879 )
PGM_PMM_III (PF02880 )
PGM_PMM_IV (PF00408 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Phosphoglucomutase-2
MAAPEGSGLGEDARLDQETAQWLRWDKNSLTLEAVKRLIAEGNKEELRKCFGARMEFGTA
GLRAAMGPGISRMNDLTIIQTTQGFCRYLEKQFSDLKQKGIVISFDARAHPSSGGSSRRF
ARLAATTFISQGIPVYLFSDITPTPFVPFTVSHLKLCAGIMITASHNPKQDNGYKVYWDN
GAQIISPHDKGISQAIEENLEPWPQAWDDSLIDSSPLLHNPSASINNDYFEDLKKYCFHR
SVNRETKVKFVHTSVHGVGHSFVQSAFKAFDLVPPEAVPEQKDPDPEFPTVKYPNPEEGK
GVLTLSFALADKTKARIVLANDPDADRLAVAEKQDSGEWRVFSGNELGALLGWWLFTSWK
EKNQDRSALKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKTVL
FAFEEAIGYMCCPFVLDKDGVSAAVISAELASFLATKNLSLSQQLKAIYVEYGYHITKAS
YFICHDQETIKKLFENLRNYDGKNNYPKACGKFEISAIRDLTTGYDDSQPDKKAVLPTSK
SSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPGNSDPEQLKKELNELVSAIEEHFF
QPQKYNLQPKAD

External Links

GenBank ID Protein

33337743

UniProtKB/Swiss-Prot ID

Q96G03

UniProtKB/Swiss-Prot Entry Name

PGM2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF109360

GeneCard ID