| Identification |
|---|
| HMDB Protein ID
| CDBP02363 |
| Secondary Accession Numbers
| Not Available |
| Name
| Mannose-1-phosphate guanyltransferase beta |
| Description
| Not Available |
| Synonyms
|
- GDP-mannose pyrophosphorylase B
- GTP-mannose-1-phosphate guanylyltransferase beta
|
| Gene Name
| GMPPB |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in transferase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| dolichol-linked oligosaccharide biosynthetic process |
| post-translational protein modification |
| protein N-linked glycosylation via asparagine |
| GDP-mannose biosynthetic process |
| Cellular Component |
| mitochondrion |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| nucleotidyltransferase activity |
| Molecular Function |
| GTP binding |
| mannose-1-phosphate guanylyltransferase activity |
| Process |
| metabolic process |
| biosynthetic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Fructose and Mannose Degradation |    |  | | GDP-alpha-D-mannose biosynthesis | Not Available | Not Available | | Fructose and mannose metabolism | Not Available | | | Amino sugar and nucleotide sugar metabolism | Not Available |  | | Fructosuria |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| 3p21.31 |
| SNPs
| GMPPB |
| Gene Sequence
|
>1083 bp
ATGAAGGCACTGATCTTAGTGGGGGGCTATGGGACGCGGCTACGGCCGCTGACGCTGAGC
ACCCCGAAGCCACTGGTGGACTTCTGCAATAAGCCCATCTTGCTGCACCAAGTGGAGGCG
CTAGCCGCGGCAGGCGTGGACCACGTGATCCTGGCCGTGAGCTACATGTCGCAGGTGCTG
GAGAAGGAAATGAAGGCACAGGAGCAGAGGCTGGGAATCCGAATCTCCATGTCCCATGAA
GAGGAGCCTTTGGGGACAGCTGGGCCCCTGGCGCTGGCCCGTGACCTACTCTCTGAGACT
GCAGACCCTTTCTTCGTCCTCAACAGTGACGTGATCTGCGATTTCCCCTTCCAAGCCATG
GTGCAGTTCCACCGGCACCATGGCCAGGAGGGCTCCATCCTGGTGACCAAGGTGGAGGAA
CCCTCCAAGTACGGTGTGGTGGTGTGTGAGGCTGACACAGGCCGCATTCACCGGTTCGTG
GAGAAGCCACAGGTGTTTGTGTCCAATAAGATCAACGCAGGCATGTACATCCTGAGCCCT
GCAGTGCTGCGGCGCATCCAGCTGCAGCCTACGTCCATTGAGAAGGAGGTCTTCCCCATT
ATGGCCAAGGAGGGGCAGCTATATGCCATGGAGTTACAGGGCTTCTGGATGGACATTGGG
CAGCCCAAGGACTTCCTCACTGGCATGTGCCTCTTCCTGCAGTCACTGAGGCAGAAGCAG
CCTGAGCGGCTGTGCTCAGGCCCTGGCATTGTGGGCAACGTGCTGGTGGACCCAAGTGCC
CGCATCGGCCAGAACTGCAGCATTGGCCCCAATGTGAGCCTGGGACCTGGCGTGGTGGTC
GAAGATGGTGTGTGTATCCGGCGGTGCACGGTGCTGCGGGATGCCCGGATCCGTTCCCAT
TCCTGGCTTGAGTCCTGCATTGTGGGCTGGCGCTGCCGCGTGGGTCAGTGGGTACGCATG
GAGAACGTGACAGTGCTGGGTGAGGACGTCATAGTTAATGATGAGCTCTACCTCAACGGA
GCCAGCGTGCTGCCCCACAAGTCTATTGGCGAGTCAGTGCCAGAGCCTCGTATCATCATG
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 360 |
| Molecular Weight
| 42649.34 |
| Theoretical pI
| 6.45 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Mannose-1-phosphate guanyltransferase beta
MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL
EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAM
VQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSP
AVLQRIQLQPTSIEKEVFPIMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQKQ
PERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDARIRSH
SWLESCIVGWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIGESVPEPRIIM
|
| External Links |
|---|
| GenBank ID Protein
| 5052351 |
| UniProtKB/Swiss-Prot ID
| Q9Y5P6 |
| UniProtKB/Swiss-Prot Entry Name
| GMPPB_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF135421 |
| GeneCard ID
| GMPPB |
| GenAtlas ID
| GMPPB |
| HGNC ID
| HGNC:22932 |
| References |
|---|
| General References
| Not Available |