Identification |
HMDB Protein ID
| CDBP02351 |
Secondary Accession Numbers
| Not Available |
Name
| Ethanolamine-phosphate phospho-lyase |
Description
| Not Available |
Synonyms
|
- Alanine--glyoxylate aminotransferase 2-like 1
|
Gene Name
| AGXT2L1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in transaminase activity |
Specific Function
| Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde.
|
GO Classification
|
Biological Process |
cellular amino acid metabolic process |
Cellular Component |
mitochondrion |
Function |
binding |
catalytic activity |
transferase activity |
transferase activity, transferring nitrogenous groups |
cofactor binding |
pyridoxal phosphate binding |
transaminase activity |
Molecular Function |
ethanolamine-phosphate phospho-lyase activity |
pyridoxal phosphate binding |
alanine-glyoxylate transaminase activity |
|
Cellular Location
|
- Mitochondrion (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 4 |
Locus
| 4q25 |
SNPs
| AGXT2L1 |
Gene Sequence
|
>1500 bp
ATGTGCGAGCTGTACAGTAAGCGGGACACTCTGGGGCTGAGGAAGAAGCACATCGGGCCC
TCATGCAAAGTTTTCTTTGCATCGGATCCCATCAAAATAGTGAGAGCCCAGAGGCAGTAC
ATGTTTGATGAGAACGGTGAACAGTACTTGGACTGCATCAACAATGTTGCCCATGTGGGA
CACTGTCACCCAGGAGTGGTCAAAGCTGCCCTGAAACAGATGGAACTGCTAAATACAAAT
TCTCGATTCCTCCACGACAACATTGTTGAGTATGCCAAACGCCTTTCAGCAACTCTGCCG
GAGAAACTCTCTGTTTGTTATTTTACAAATTCAGGATCCGAAGCCAACGACTTAGCCTTA
CGCCTGGCTCGGCAGTTCAGAGGCCACCAGGATGTGATCACTCTTGACCATGCTTACCAT
GGTCACCTATCATCCTTAATTGAGATTAGCCCATATAAGTTTCAGAAAGGAAAAGATGTC
AAAAAAGAATTTGTACATGTGGCACCAACTCCAGATACTTACAGAGGAAAATATAGAGAA
GACCATGCAGACTCAGCCAGTGCTTATGCAGATGAAGTGAAGAAAATCATTGAAGATGCT
CATAACAGTGGAAGGAAGATTGCTGCCTTTATTGCTGAATCCATGCAGAGTTGTGGCGGA
CAAATAATTCCTCCAGCAGGCTACTTCCAGAAAGTGGCAGAATATGTACACGGTGCAGGG
GGTGTGTTTATAGCTGATGAAGTTCAAGTGGGCTTTGGCAGAGTTGGGAAACATTTCTGG
AGCTTCCAGATGTATGGTGAAGACTTTGTTCCAGACATCGTCACAATGGGAAAACCGATG
GGCAACGGCCACCCGGTGGCATGTGTGGTAACAACCAAAGAAATTGCAGAAGCCTTCAGC
AGCTCTGGGATGGAATATTTTAATACGTATGGAGGAAATCCAGTATCTTGTGCTGTTGGT
TTGGCTGTCCTGGATATAATTGAAAATGAAGACCTTCAAGGAAATGCCAAGAGAGTAGGG
AATTATCTCACTGAGTTACTGAAAAAACAGAAGGCTAAACACACTTTGATAGGAGATATT
AGGGGCATTGGCCTTTTTATTGGAATTGATTTAGTGAAGGACCATCTGAAAAGGACCCCT
GCCACAGCTGAAGCTCAGCACATCATCTACAAGATGAAAGAAAAACGAGTGCTTCTCAGT
GCCGATGGACCTCATAGAAATGTACTTAAAATAAAACCACCTATGTGCTTCACTGAAGAA
GATGCAAAGTTCATGGTGGACCAACTTGATAGGATTCTAACAGTTTTAGAAGAAGCTATG
GGAACCAAAACCGAAAGTGTGACCTCTGAGAATACTCCATGCAAAACAAAGATGCTGAAA
GAAGCCCACATAGAACTGCTTAGGGACAGCACCACTGACTCCAAAGAAAATCCCAGCAGA
AAGAGAAATGGAATGTGCACGGATACACATTCACTGCTCAGTAAGAGGCTCAAGACATGA
|
Protein Properties |
Number of Residues
| 499 |
Molecular Weight
| 55039.64 |
Theoretical pI
| 8.14 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Alanine--glyoxylate aminotransferase 2-like 1
MCELYSKRDTLGLRKKHIGPSCKVFFASDPIKIVRAQRQYMFDENGEQYLDCINNVAHVG
HCHPGVVKAALKQMELLNTNSRFLHDNIVEYAKRLSATLPEKLSVCYFTNSGSEANDLAL
RLARQFRGHQDVITLDHAYHGHLSSLIEISPYKFQKGKDVKKEFVHVAPTPDTYRGKYRE
DHADSASAYADEVKKIIEDAHNSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEYVHGAG
GVFIADEVQVGFGRVGKHFWSFQMYGEDFVPDIVTMGKPMGNGHPVACVVTTKEIAEAFS
SSGMEYFNTYGGNPVSCAVGLAVLDIIENEDLQGNAKRVGNYLTELLKKQKAKHTLIGDI
RGIGLFIGIDLVKDHLKRTPATAEAQHIIYKMKEKRVLLSADGPHRNVLKIKPPMCFTEE
DAKFMVDQLDRILTVLEEAMGTKTESVTSENTPCKTKMLKEAHIELLRDSTTDSKENPSR
KRNGMCTDTHSLLSKRLKT
|
External Links |
GenBank ID Protein
| 63992119 |
UniProtKB/Swiss-Prot ID
| Q8TBG4 |
UniProtKB/Swiss-Prot Entry Name
| AT2L1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AC097473 |
GeneCard ID
| AGXT2L1 |
GenAtlas ID
| AGXT2L1 |
HGNC ID
| HGNC:14404 |
References |
General References
| Not Available |