| Identification |
|---|
| HMDB Protein ID
| CDBP02351 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ethanolamine-phosphate phospho-lyase |
| Description
| Not Available |
| Synonyms
|
- Alanine--glyoxylate aminotransferase 2-like 1
|
| Gene Name
| AGXT2L1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in transaminase activity |
| Specific Function
| Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde.
|
| GO Classification
|
| Biological Process |
| cellular amino acid metabolic process |
| Cellular Component |
| mitochondrion |
| Function |
| transaminase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring nitrogenous groups |
| cofactor binding |
| pyridoxal phosphate binding |
| Molecular Function |
| pyridoxal phosphate binding |
| alanine-glyoxylate transaminase activity |
| ethanolamine-phosphate phospho-lyase activity |
|
| Cellular Location
|
- Mitochondrion (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| 4q25 |
| SNPs
| AGXT2L1 |
| Gene Sequence
|
>1500 bp
ATGTGCGAGCTGTACAGTAAGCGGGACACTCTGGGGCTGAGGAAGAAGCACATCGGGCCC
TCATGCAAAGTTTTCTTTGCATCGGATCCCATCAAAATAGTGAGAGCCCAGAGGCAGTAC
ATGTTTGATGAGAACGGTGAACAGTACTTGGACTGCATCAACAATGTTGCCCATGTGGGA
CACTGTCACCCAGGAGTGGTCAAAGCTGCCCTGAAACAGATGGAACTGCTAAATACAAAT
TCTCGATTCCTCCACGACAACATTGTTGAGTATGCCAAACGCCTTTCAGCAACTCTGCCG
GAGAAACTCTCTGTTTGTTATTTTACAAATTCAGGATCCGAAGCCAACGACTTAGCCTTA
CGCCTGGCTCGGCAGTTCAGAGGCCACCAGGATGTGATCACTCTTGACCATGCTTACCAT
GGTCACCTATCATCCTTAATTGAGATTAGCCCATATAAGTTTCAGAAAGGAAAAGATGTC
AAAAAAGAATTTGTACATGTGGCACCAACTCCAGATACTTACAGAGGAAAATATAGAGAA
GACCATGCAGACTCAGCCAGTGCTTATGCAGATGAAGTGAAGAAAATCATTGAAGATGCT
CATAACAGTGGAAGGAAGATTGCTGCCTTTATTGCTGAATCCATGCAGAGTTGTGGCGGA
CAAATAATTCCTCCAGCAGGCTACTTCCAGAAAGTGGCAGAATATGTACACGGTGCAGGG
GGTGTGTTTATAGCTGATGAAGTTCAAGTGGGCTTTGGCAGAGTTGGGAAACATTTCTGG
AGCTTCCAGATGTATGGTGAAGACTTTGTTCCAGACATCGTCACAATGGGAAAACCGATG
GGCAACGGCCACCCGGTGGCATGTGTGGTAACAACCAAAGAAATTGCAGAAGCCTTCAGC
AGCTCTGGGATGGAATATTTTAATACGTATGGAGGAAATCCAGTATCTTGTGCTGTTGGT
TTGGCTGTCCTGGATATAATTGAAAATGAAGACCTTCAAGGAAATGCCAAGAGAGTAGGG
AATTATCTCACTGAGTTACTGAAAAAACAGAAGGCTAAACACACTTTGATAGGAGATATT
AGGGGCATTGGCCTTTTTATTGGAATTGATTTAGTGAAGGACCATCTGAAAAGGACCCCT
GCCACAGCTGAAGCTCAGCACATCATCTACAAGATGAAAGAAAAACGAGTGCTTCTCAGT
GCCGATGGACCTCATAGAAATGTACTTAAAATAAAACCACCTATGTGCTTCACTGAAGAA
GATGCAAAGTTCATGGTGGACCAACTTGATAGGATTCTAACAGTTTTAGAAGAAGCTATG
GGAACCAAAACCGAAAGTGTGACCTCTGAGAATACTCCATGCAAAACAAAGATGCTGAAA
GAAGCCCACATAGAACTGCTTAGGGACAGCACCACTGACTCCAAAGAAAATCCCAGCAGA
AAGAGAAATGGAATGTGCACGGATACACATTCACTGCTCAGTAAGAGGCTCAAGACATGA
|
| Protein Properties |
|---|
| Number of Residues
| 499 |
| Molecular Weight
| 55039.64 |
| Theoretical pI
| 8.14 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Alanine--glyoxylate aminotransferase 2-like 1
MCELYSKRDTLGLRKKHIGPSCKVFFASDPIKIVRAQRQYMFDENGEQYLDCINNVAHVG
HCHPGVVKAALKQMELLNTNSRFLHDNIVEYAKRLSATLPEKLSVCYFTNSGSEANDLAL
RLARQFRGHQDVITLDHAYHGHLSSLIEISPYKFQKGKDVKKEFVHVAPTPDTYRGKYRE
DHADSASAYADEVKKIIEDAHNSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEYVHGAG
GVFIADEVQVGFGRVGKHFWSFQMYGEDFVPDIVTMGKPMGNGHPVACVVTTKEIAEAFS
SSGMEYFNTYGGNPVSCAVGLAVLDIIENEDLQGNAKRVGNYLTELLKKQKAKHTLIGDI
RGIGLFIGIDLVKDHLKRTPATAEAQHIIYKMKEKRVLLSADGPHRNVLKIKPPMCFTEE
DAKFMVDQLDRILTVLEEAMGTKTESVTSENTPCKTKMLKEAHIELLRDSTTDSKENPSR
KRNGMCTDTHSLLSKRLKT
|
| External Links |
|---|
| GenBank ID Protein
| 63992119 |
| UniProtKB/Swiss-Prot ID
| Q8TBG4 |
| UniProtKB/Swiss-Prot Entry Name
| AT2L1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AC097473 |
| GeneCard ID
| AGXT2L1 |
| GenAtlas ID
| AGXT2L1 |
| HGNC ID
| HGNC:14404 |
| References |
|---|
| General References
| Not Available |