| Identification |
|---|
| HMDB Protein ID
| CDBP02339 |
| Secondary Accession Numbers
| Not Available |
| Name
| Thioredoxin reductase 2 isoform 1 variant |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| Not Available |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in oxidoreductase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Component |
| cell part |
| intracellular part |
| cytoplasm |
| Function |
| oxidoreductase activity, acting on a sulfur group of donors, nad or nadp as acceptor |
| fad or fadh2 binding |
| binding |
| nucleotide binding |
| catalytic activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| nadp or nadph binding |
| antioxidant activity |
| thioredoxin-disulfide reductase activity |
| oxidoreductase activity |
| oxidoreductase activity, acting on nadh or nadph |
| Process |
| metabolic process |
| cellular process |
| oxidation reduction |
| cellular homeostasis |
| cell redox homeostasis |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
>1536 bp
GGAGGGCGCTTCCGGTGGCGGACGCAGGCCGTGGCGGGCGGGGTGCGGGGCGCGGCGCGG
GGCGCAGCAGCAGGTCAGCGGGACTATGATCTCCTGGTGGTCGGCGGGGGATCTGGTGGC
CTGGCTTGTGCCAAGGAGGCCGCTCAGCTGGGAAGGAAGGTGTCCGTGGTGGACTACGTG
GAACCTTCTCCCCAAGGCACCCGGTGGGGCCTCGGCGGCACCTGCGTCAACGTGGGCTGC
ATCCCCAAGAAGCTGATGCACCAGGCGGCACTGCTGGGAGGCCTGATCCAAGATGCCCCC
AACTATGGCTGGGAGGTGGCCCAGCCCGTGCCGCATGACTGGAGGAAGATGGCAGAAGCT
GTTCAAAATCACGTGAAATCCTTGAACTGGGGCCACCGTGTCCAGCTTCAGGACAGAAAA
GTCAAGTACTTTAACATCAAAGCCAGCTTTGTTGACGAGCACACGGTTTGCGGCGTTGCC
AAAGGTGGGAAAGAGATTCTGCTGTCAGCCGATCACATCATCATTGCTACTGGAGGGCGG
CCGAGATACCCCACGCACATCGAAGGTGCCTTGGAATATGGAATCACAAGTGATGACATC
TTCTGGCTGAAGGAATCCCCTGGAAAAACGTTGGTGGTCGGGGCCAGCTATGTGGCCCTG
GAGTGTGCTGGCTTCCTCACCGGGATTGGGCTGGACACCACCATCATGATGCGCAGCATC
CCCCTCCGCGGCTTCGACCAGCAAATGTCCTCCATGGTCATAGAGCACATGGCATCTCAT
GGCACCCGGTTCCTGAGGGGCTGTGCCCCCTCGCGGGTCAGGAGGCTCCCTGATGGCCAG
CTGCAGGTCACCTGGGAGGACAGCACCACCGGCAAGGAGGACACGGGCACCTTTGACACC
GTCCTGTGGGCCATAGGTCGAGTCCCAGACACCAGAAGTCTGAATTTGGAGAAGGCTGGG
GTAGATACTAGCCCCGACACTCAGAAGATCCTGGTGGACTCCCGGGAAGCCACCTCTGTG
CCCCACATCTACGCCATTGGTGACGTGGTGGAGGGGCGGCCTGAGCTGACACCCACAGCG
ATCATGGCCGGGAGGCTCCTGGTGCAGCGGCTCTTCGGCGGGTCCTCAGATCTGATGGAC
TACGACAATGTTCCCACGACCGTCTTCACCCCGCTGGAGTATGGCTGTGTGGGGCTGTCC
GAGGAGGAGGCAGTGGCTCGCCACGGGCAGGAGCATGTTGAGGTCTATCACGCCCATTAT
AAACCACTGGAGTTCACGGTGGCTGGACGAGATGCATCCCAGTGTTATGTAAAGATGGTG
TGCCTGAGGGAGCCCCCACAGCTGGTGCTGGGCCTGCATTTCCTTGGCCCCAACGCAGGC
GAAGTTACTCAAGGATTTGCTCTGGGGATCAAGTGTGGGGCTTCCTATGCGCAGGTGATG
CGGACCGTGGGTATCCATCCCACATGCTCTGAGGAGGTAGTCAAGCTGCGCATCTCCAAG
CGCTCAGGCCTGGACCCCACGGTGACAGGCTGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 511 |
| Molecular Weight
| 55217.7 |
| Theoretical pI
| 7.37 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Thioredoxin reductase 2 isoform 1 variant
GGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVSVVDYV
EPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEA
VQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGR
PRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSI
PLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDT
VLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPTA
IMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHY
KPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVM
RTVGIHPTCSEEVVKLRISKRSGLDPTVTGC
|
| External Links |
|---|
| GenBank ID Protein
| 62089028 |
| UniProtKB/Swiss-Prot ID
| Q59ET7 |
| UniProtKB/Swiss-Prot Entry Name
| Q59ET7_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB209724 |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:18155 |
| References |
|---|
| General References
| Not Available |