Identification |
HMDB Protein ID
| CDBP02337 |
Secondary Accession Numbers
| Not Available |
Name
| Threonine synthase-like 1 |
Description
| Not Available |
Synonyms
|
- TSH1
|
Gene Name
| THNSL1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in catalytic activity |
Specific Function
| Not Available |
GO Classification
|
Function |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
lyase activity |
carbon-oxygen lyase activity |
cofactor binding |
pyridoxal phosphate binding |
carbon-oxygen lyase activity, acting on phosphates |
threonine synthase activity |
shikimate kinase activity |
binding |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
Process |
threonine metabolic process |
threonine biosynthetic process |
aspartate family amino acid metabolic process |
metabolic process |
cellular metabolic process |
cellular amino acid and derivative metabolic process |
cellular amino acid metabolic process |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 10p12.1 |
SNPs
| THNSL1 |
Gene Sequence
|
>2232 bp
ATGCTCCACTTTAACCGATGTCATCATCTGAAAAAGATAACACAGAAATGTTTTTCTAGT
ATACATGTTAAAACGGATAAACATGCACAGCGATTTCTTTCAAGAACCTTTGCACTTGCG
GAATTGAGGAAGTCATGGTATTCAACCCACTCTCTTGTTGGAGACAAAAATATTATCCTG
ATGGGACCTCCTGGTGCTGGGAAAACAACAGTAGGCAGAATAATAGGTCAGAAACTAGGT
TGTTGTGTCATAGATGTGGATGATGATATCCTTGAAAAAACCTGGAATATGAGTGTGTCT
GAAAAATTACAGGATGTTGGTAATGAGCAATTTTTAGAAGAGGAAGGAAAAGCTGTGTTA
AACTTCTCTGCATCTGGAAGTGTGATTTCCCTTACTGGGTCCAATCCAATGCATGATGCT
AGCATGTGGCATCTGAAGAAAAATGGAATAATTGTATACCTGGATGTACCTCTACTAGAT
CTAATTTGTCGTCTAAAATTAATGAAGACAGATAGGATTGTAGGTCAGAATTCTGGAACA
TCTATGAAAGACTTACTTAAATTTAGAAGACAGTATTATAAGAAGTGGTATGATGCTCGT
GTTTTCTGTGAAAGTGGGGCTTCCCCAGAGGAGGTAGCTGACAAAGTGCTGAATGCAATT
AAAAGATACCAAGATGTGGACTCGGAAACATTCATTTCAACAAGACACGTTTGGCCTGAA
GACTGTGAACAGAAGGTTTCAGCAAAATTCTTTAGTGAAGCTGTAATTGAGGGGTTGGCT
TCTGATGGTGGCCTCTTTGTTCCTGCAAAGGAGTTTCCAAAATTAAGCTGCGGGGAGTGG
AAAAGCCTAGTAGGAGCAACCTACGTAGAAAGAGCACAGATACTGTTGGAAAGATGTATC
CATCCTGCAGACATACCTGCTGCCAGGTTGGGAGAAATGATTGAAACTGCTTATGGGGAA
AACTTTGCCTGCTCAAAAATTGCTCCTGTCAGGCACCTTTCAGGCAACCAGTTCATCCTG
GAGTTGTTTCATGGACCAACAGGATCATTTAAAGATTTGTCTTTACAGCTTATGCCTCAT
ATTTTTGCACACTGTATCCCACCAAGTTGCAATTATATGATACTTGTAGCTACTTCAGGA
GACACAGGGAGTGCAGTCTTAAATGGTTTTAGTCGTCTAAATAAGAATGATAAGCAAAGG
ATAGCTGTGGTTGCATTTTTTCCTGAGAATGGAGTAAGTGATTTTCAAAAAGCACAAATA
ATTGGCAGTCAGAGAGAAAATGGATGGGCAGTGGGTGTTGAGTCAGATTTTGATTTTTGC
CAGACAGCTATAAAAAGAATTTTTAATGATTCTGATTTTACTGGCTTTCTTACTGTGGAA
TATGGAACAATCTTAAGTTCGGCTAACTCCATAAACTGGGGCCGACTACTTCCGCAGGTA
GTTTATCATGCTTCCGCATATCTTGATCTTGTTAGTCAAGGATTTATTTCTTTTGGAAGC
CCAGTCGATGTCTGTATTCCCACAGGAAACTTTGGTAACATTTTAGCAGCAGTGTATGCC
AAAATGATGGGAATCCCGATTCGAAAATTTATCTGTGCCTCTAATCAGAACCATGTTTTG
ACTGATTTTATAAAAACAGGACATTATGATCTAAGGGAAAGAAAACTAGCACAAACCTTT
TCACCGTCAATAGATATTCTCAAATCTTCAAACCTAGAACGACATTTACACTTGATGGCT
AATAAAGATGGACAGCTAATGACAGAATTATTTAATCGATTAGAAAGTCAGCATCATTTC
CAGATAGAAAAGGCTCTAGTTGAGAAACTTCAGCAGGATTTTGTAGCTGACTGGTGCTCT
GAGGGAGAGTGCCTAGCAGCTATTAACTCCACCTATAATACTTCAGGGTATATTTTGGAT
CCACACACTGCTGTTGCAAAAGTGGTTGCAGATAGGGTGCAAGACAAAACTTGCCCTGTG
ATTATCTCATCTACAGCCCATTACTCAAAGTTTGCACCTGCTATCATGCAGGCTTTAAAG
ATTAAAGAAATCAATGAGACTTCATCAAGTCAGCTCTATTTGCTGGGTTCATACAATGCA
TTACCTCCACTGCATGAGGCTTTATTAGAGAGAACAAAACAGCAAGAGAAGATGGAGTAC
CAGGTCTGTGCAGCTGATATGAATGTCTTGAAGAGTCATGTGGAACAACTTGTCCAAAAT
CAATTCATATGA
|
Protein Properties |
Number of Residues
| 743 |
Molecular Weight
| 83069.5 |
Theoretical pI
| 7.13 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Threonine synthase-like 1
MLHFNRCHHLKKITQKCFSSIHVKTDKHAQRFLSRTFALAELRKSWYSTHSLVGDKNIIL
MGPPGAGKTTVGRIIGQKLGCCVIDVDDDILEKTWNMSVSEKLQDVGNEQFLEEEGKAVL
NFSASGSVISLTGSNPMHDASMWHLKKNGIIVYLDVPLLDLICRLKLMKTDRIVGQNSGT
SMKDLLKFRRQYYKKWYDARVFCESGASPEEVADKVLNAIKRYQDVDSETFISTRHVWPE
DCEQKVSAKFFSEAVIEGLASDGGLFVPAKEFPKLSCGEWKSLVGATYVERAQILLERCI
HPADIPAARLGEMIETAYGENFACSKIAPVRHLSGNQFILELFHGPTGSFKDLSLQLMPH
IFAHCIPPSCNYMILVATSGDTGSAVLNGFSRLNKNDKQRIAVVAFFPENGVSDFQKAQI
IGSQRENGWAVGVESDFDFCQTAIKRIFNDSDFTGFLTVEYGTILSSANSINWGRLLPQV
VYHASAYLDLVSQGFISFGSPVDVCIPTGNFGNILAAVYAKMMGIPIRKFICASNQNHVL
TDFIKTGHYDLRERKLAQTFSPSIDILKSSNLERHLHLMANKDGQLMTELFNRLESQHHF
QIEKALVEKLQQDFVADWCSEGECLAAINSTYNTSGYILDPHTAVAKVVADRVQDKTCPV
IISSTAHYSKFAPAIMQALKIKEINETSSSQLYLLGSYNALPPLHEALLERTKQQEKMEY
QVCAADMNVLKSHVEQLVQNQFI
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q8IYQ7 |
UniProtKB/Swiss-Prot Entry Name
| THNS1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AK125249 |
GeneCard ID
| THNSL1 |
GenAtlas ID
| THNSL1 |
HGNC ID
| HGNC:26160 |
References |
General References
| Not Available |