Identification
HMDB Protein ID CDBP02318
Secondary Accession Numbers Not Available
Name Sodium-dependent phosphate transport protein 1
Description Not Available
Synonyms
  1. Na(+)/PI cotransporter 1
  2. Na/Pi-4
  3. Renal Na(+)-dependent phosphate cotransporter 1
  4. Renal sodium-dependent phosphate transport protein 1
  5. Renal sodium-phosphate transport protein 1
  6. Sodium/phosphate cotransporter 1
  7. Solute carrier family 17 member 1
Gene Name SLC17A1
Protein Type Transporter
Biological Properties
General Function Involved in transmembrane transport
Specific Function Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.
GO Classification
Biological Process
urate metabolic process
sodium ion transport
Cellular Component
integral to plasma membrane
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
ion transmembrane transporter activity
transporter activity
anion transmembrane transporter activity
inorganic anion transmembrane transporter activity
phosphate transmembrane transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
Molecular Function
symporter activity
sodium-dependent phosphate transmembrane transporter activity
Process
establishment of localization
transport
phosphate transport
transmembrane transport
anion transport
inorganic anion transport
ion transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location 6
Locus 6p22.2
SNPs SLC17A1
Gene Sequence
>1404 bp
ATGCAAATGGATAACCGGTTGCCTCCCAAAAAAGTTCCAGGTTTCTGTTCCTTTCGCTAT
GGATTGTCTTTCCTTGTGCACTGTTGTAATGTTATAATAACAGCACAGCGTGCGTGCCTG
AACCTCACAATGGTAGTCATGGTGAATAGCACAGATCCACATGGTTTGCCCAACACCTCC
ACAAAGAAGCTCCTGGATAATATAAAGAACCCTATGTATAATTGGAGCCCAGATATCCAG
GGAATCATCTTGAGTTCCACCTCCTATGGTGTCATCATCATCCAAGTTCCTGTTGGATAC
TTCTCTGGAATATATTCTACAAAGAAAATGATTGGCTTTGCATTATGCCTCAGCTCTGTG
TTAAGCCTGCTCATCCCACCAGCAGCTGGAATTGGAGTAGCTTGGGTCGTTGTATGTCGA
GCAGTTCAGGGAGCAGCCCAGGGGATAGTTGCAACAGCCCAGTTTGAAATATATGTCAAA
TGGGCTCCTCCCCTGGAACGAGGCCGACTTACTTCTATGAGTACATCAGGGTTTTTGCTG
GGACCCTTTATTGTCCTACTTGTGACTGGAGTTATCTGTGAATCTCTGGGCTGGCCCATG
GTCTTCTATATTTTTGGTGCTTGTGGCTGTGCCGTATGTCTTCTCTGGTTCGTTCTGTTT
TATGATGACCCCAAAGACCACCCATGTATAAGCATCAGTGAAAAGGAATACATCACATCC
TCCCTGGTCCAGCAGGTCAGTTCAAGTAGACAATCTCTGCCTATCAAGGCTATACTTAAG
TCGCTTCCAGTCTGGGCTATTTCCACTGGTAGTTTTACGTTTTTCTGGTCACATAACATC
ATGACACTATACACTCCAATGTTTATCAACTCCATGCTTCATGTTAATATAAAAGAGAAT
GGGTTCTTGTCTTCCCTTCCCTATTTGTTTGCCTGGATCTGTGGTAACCTAGCAGGTCAG
TTATCAGACTTCTTCCTGACCAGGAATATTCTCAGCGTAATTGCTGTCCGGAAACTCTTC
ACAGCAGCAGGATTTCTCCTTCCTGCAATCTTTGGTGTCTGCCTGCCTTACCTGAGTTCC
ACCTTCTACAGCATTGTCATTTTCCTAATACTTGCTGGTGCAACAGGCAGCTTTTGCTTG
GGTGGAGTGTTTATAAATGGCTTGGATATTGCTCCCAGATATTTTGGATTTATTAAAGCA
TGTTCAACTTTAACTGGAATGATAGGAGGACTAATTGCTTCCACTTTGACTGGATTGATC
CTTAAGCAGGATCCGGAATCCGCCTGGTTTAAAACCTTCATCCTGATGGCAGCCATTAAT
GTGACTGGCCTAATTTTCTACCTTATAGTTGCTACAGCAGAAATTCAGGACTGGGCTAAA
GAAAAACAACACACACGTCTCTGA
Protein Properties
Number of Residues 467
Molecular Weight 51131.04
Theoretical pI 8.565
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Sodium-dependent phosphate transport protein 1
MQMDNRLPPKKVPGFCSFRYGLSFLVHCCNVIITAQRACLNLTMVVMVNSTDPHGLPNTS
TKKLLDNIKNPMYNWSPDIQGIILSSTSYGVIIIQVPVGYFSGIYSTKKMIGFALCLSSV
LSLLIPPAAGIGVAWVVVCRAVQGAAQGIVATAQFEIYVKWAPPLERGRLTSMSTSGFLL
GPFIVLLVTGVICESLGWPMVFYIFGACGCAVCLLWFVLFYDDPKDHPCISISEKEYITS
SLVQQVSSSRQSLPIKAILKSLPVWAISTGSFTFFWSHNIMTLYTPMFINSMLHVNIKEN
GFLSSLPYLFAWICGNLAGQLSDFFLTRNILSVIAVRKLFTAAGFLLPAIFGVCLPYLSS
TFYSIVIFLILAGATGSFCLGGVFINGLDIAPRYFGFIKACSTLTGMIGGLIASTLTGLI
LKQDPESAWFKTFILMAAINVTGLIFYLIVATAEIQDWAKEKQHTRL
GenBank ID Protein 154800443
UniProtKB/Swiss-Prot ID Q14916
UniProtKB/Swiss-Prot Entry Name NPT1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_005074.3
GeneCard ID SLC17A1
GenAtlas ID SLC17A1
HGNC ID HGNC:10929
References
General References Not Available