Identification |
HMDB Protein ID
| CDBP02318 |
Secondary Accession Numbers
| Not Available |
Name
| Sodium-dependent phosphate transport protein 1 |
Description
| Not Available |
Synonyms
|
- Na(+)/PI cotransporter 1
- Na/Pi-4
- Renal Na(+)-dependent phosphate cotransporter 1
- Renal sodium-dependent phosphate transport protein 1
- Renal sodium-phosphate transport protein 1
- Sodium/phosphate cotransporter 1
- Solute carrier family 17 member 1
|
Gene Name
| SLC17A1 |
Protein Type
| Transporter |
Biological Properties |
General Function
| Involved in transmembrane transport |
Specific Function
| Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.
|
GO Classification
|
Biological Process |
urate metabolic process |
sodium ion transport |
Cellular Component |
integral to plasma membrane |
Component |
cell part |
membrane part |
intrinsic to membrane |
integral to membrane |
Function |
ion transmembrane transporter activity |
transporter activity |
anion transmembrane transporter activity |
inorganic anion transmembrane transporter activity |
phosphate transmembrane transporter activity |
transmembrane transporter activity |
substrate-specific transmembrane transporter activity |
Molecular Function |
symporter activity |
sodium-dependent phosphate transmembrane transporter activity |
Process |
establishment of localization |
transport |
phosphate transport |
transmembrane transport |
anion transport |
inorganic anion transport |
ion transport |
|
Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 6 |
Locus
| 6p22.2 |
SNPs
| SLC17A1 |
Gene Sequence
|
>1404 bp
ATGCAAATGGATAACCGGTTGCCTCCCAAAAAAGTTCCAGGTTTCTGTTCCTTTCGCTAT
GGATTGTCTTTCCTTGTGCACTGTTGTAATGTTATAATAACAGCACAGCGTGCGTGCCTG
AACCTCACAATGGTAGTCATGGTGAATAGCACAGATCCACATGGTTTGCCCAACACCTCC
ACAAAGAAGCTCCTGGATAATATAAAGAACCCTATGTATAATTGGAGCCCAGATATCCAG
GGAATCATCTTGAGTTCCACCTCCTATGGTGTCATCATCATCCAAGTTCCTGTTGGATAC
TTCTCTGGAATATATTCTACAAAGAAAATGATTGGCTTTGCATTATGCCTCAGCTCTGTG
TTAAGCCTGCTCATCCCACCAGCAGCTGGAATTGGAGTAGCTTGGGTCGTTGTATGTCGA
GCAGTTCAGGGAGCAGCCCAGGGGATAGTTGCAACAGCCCAGTTTGAAATATATGTCAAA
TGGGCTCCTCCCCTGGAACGAGGCCGACTTACTTCTATGAGTACATCAGGGTTTTTGCTG
GGACCCTTTATTGTCCTACTTGTGACTGGAGTTATCTGTGAATCTCTGGGCTGGCCCATG
GTCTTCTATATTTTTGGTGCTTGTGGCTGTGCCGTATGTCTTCTCTGGTTCGTTCTGTTT
TATGATGACCCCAAAGACCACCCATGTATAAGCATCAGTGAAAAGGAATACATCACATCC
TCCCTGGTCCAGCAGGTCAGTTCAAGTAGACAATCTCTGCCTATCAAGGCTATACTTAAG
TCGCTTCCAGTCTGGGCTATTTCCACTGGTAGTTTTACGTTTTTCTGGTCACATAACATC
ATGACACTATACACTCCAATGTTTATCAACTCCATGCTTCATGTTAATATAAAAGAGAAT
GGGTTCTTGTCTTCCCTTCCCTATTTGTTTGCCTGGATCTGTGGTAACCTAGCAGGTCAG
TTATCAGACTTCTTCCTGACCAGGAATATTCTCAGCGTAATTGCTGTCCGGAAACTCTTC
ACAGCAGCAGGATTTCTCCTTCCTGCAATCTTTGGTGTCTGCCTGCCTTACCTGAGTTCC
ACCTTCTACAGCATTGTCATTTTCCTAATACTTGCTGGTGCAACAGGCAGCTTTTGCTTG
GGTGGAGTGTTTATAAATGGCTTGGATATTGCTCCCAGATATTTTGGATTTATTAAAGCA
TGTTCAACTTTAACTGGAATGATAGGAGGACTAATTGCTTCCACTTTGACTGGATTGATC
CTTAAGCAGGATCCGGAATCCGCCTGGTTTAAAACCTTCATCCTGATGGCAGCCATTAAT
GTGACTGGCCTAATTTTCTACCTTATAGTTGCTACAGCAGAAATTCAGGACTGGGCTAAA
GAAAAACAACACACACGTCTCTGA
|
Protein Properties |
Number of Residues
| 467 |
Molecular Weight
| 51131.04 |
Theoretical pI
| 8.565 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Sodium-dependent phosphate transport protein 1
MQMDNRLPPKKVPGFCSFRYGLSFLVHCCNVIITAQRACLNLTMVVMVNSTDPHGLPNTS
TKKLLDNIKNPMYNWSPDIQGIILSSTSYGVIIIQVPVGYFSGIYSTKKMIGFALCLSSV
LSLLIPPAAGIGVAWVVVCRAVQGAAQGIVATAQFEIYVKWAPPLERGRLTSMSTSGFLL
GPFIVLLVTGVICESLGWPMVFYIFGACGCAVCLLWFVLFYDDPKDHPCISISEKEYITS
SLVQQVSSSRQSLPIKAILKSLPVWAISTGSFTFFWSHNIMTLYTPMFINSMLHVNIKEN
GFLSSLPYLFAWICGNLAGQLSDFFLTRNILSVIAVRKLFTAAGFLLPAIFGVCLPYLSS
TFYSIVIFLILAGATGSFCLGGVFINGLDIAPRYFGFIKACSTLTGMIGGLIASTLTGLI
LKQDPESAWFKTFILMAAINVTGLIFYLIVATAEIQDWAKEKQHTRL
|
External Links |
GenBank ID Protein
| 154800443 |
UniProtKB/Swiss-Prot ID
| Q14916 |
UniProtKB/Swiss-Prot Entry Name
| NPT1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_005074.3 |
GeneCard ID
| SLC17A1 |
GenAtlas ID
| SLC17A1 |
HGNC ID
| HGNC:10929 |
References |
General References
| Not Available |