Identification
HMDB Protein ID CDBP02282
Secondary Accession Numbers Not Available
Name Folate receptor gamma
Description Not Available
Synonyms
  1. FR-gamma
  2. Folate receptor 3
Gene Name FOLR3
Protein Type Enzyme
Biological Properties
General Function Involved in folic acid binding
Specific Function Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate
GO Classification Not Available
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 11q13
SNPs FOLR3
Gene Sequence
>732 bp
ATGGCCTGGCAGATGATGCAGCTGCTGCTTCTGGCTTTGGTGACTGCTGCGGGGAGTGCC
CAGCCCAGGAGTGCGCGGGCCAGGACGGACCTGCTCAATGTCTGCATGAACGCCAAGCAC
CACAAGACACAGCCCAGCCCCGAGGACGAGCTGTATGGCCAGTGCAGTCCCTGGAAGAAG
AATGCCTGCTGCACGGCCAGCACCAGCCAGGAGCTGCACAAGGACACCTCCCGCCTGTAC
AACTTTAACTGGGATCACTGTGGTAAGATGGAACCCACCTGCAAGCGCCACTTTATCCAG
GACAGCTGTCTCTATGAGTGCTCACCCAACCTGGGGCCCTGGATCCGGCAGGTCAACCAG
AGCTGGCGCAAAGAGCGCATTCTGAACGTGCCCCTGTGCAAAGAGGACTGTGAGCGCTGG
TGGGAGGACTGTCGCACCTCCTACACCTGCAAAAGCAACTGGCACAAAGGCTGGAATTGG
ACCTCAGGGATTAATGAGTGTCCGGCCGGGGCCCTCTGCAGCACCTTTGAGTCCTACTTC
CCCACTCCAGCCGCCCTTTGTGAAGGCCTCTGGAGCCACTCCTTCAAGGTCAGCAACTAT
AGTCGAGGGAGCGGCCGCTGCATCCAGATGTGGTTTGACTCAGCCCAGGGCAACCCCAAT
GAGGAGGTGGCCAAGTTCTATGCTGCGGCCATGAATGCTGGGGCCCCGTCTCGTGGGATT
ATTGATTCCTGA
Protein Properties
Number of Residues 243
Molecular Weight 27638.0
Theoretical pI 7.88
Pfam Domain Function
Signals
  • ["1-23"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Folate receptor gamma
MAWQMMQLLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCSPWKK
NACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIRQVNQ
SWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTFESYF
PTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAMNAGAPSRGI
IDS
GenBank ID Protein 473236
UniProtKB/Swiss-Prot ID P41439
UniProtKB/Swiss-Prot Entry Name FOLR3_HUMAN
PDB IDs Not Available
GenBank Gene ID Z32564
GeneCard ID FOLR3
GenAtlas ID FOLR3
HGNC ID HGNC:3795
References
General References Not Available