Identification
HMDB Protein ID CDBP02275
Secondary Accession Numbers Not Available
Name Pyrroline-5-carboxylate reductase
Description Not Available
Synonyms Not Available
Gene Name P5CR2
Protein Type Enzyme
Biological Properties
General Function Involved in oxidoreductase activity
Specific Function L-proline + NAD(P)(+) = 1-pyrroline-5- carboxylate + NAD(P)H
GO Classification
Function
catalytic activity
pyrroline-5-carboxylate reductase activity
oxidoreductase activity, acting on the ch-nh group of donors
oxidoreductase activity, acting on the ch-nh group of donors, nad or nadp as acceptor
oxidoreductase activity
Process
metabolic process
cellular metabolic process
glutamine family amino acid metabolic process
proline metabolic process
proline biosynthetic process
oxidation reduction
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs P5CR2
Gene Sequence
>960 bp
ATGAGCGTGGGCTTCATCGGGGCCGGCCAGCTGGCTATGCTCTGGCGCGGGGCTTCACGG
CCGCAGATTCCTGTCGGCTCACAAGATAATAGCCAGCTCCCCAGAAATGAACCTGCCCAC
GGTGTCCGCGCTCAGGAAGATGGGTGTGAACCTGACACGCAGCAACAAGGAGACGGTGAA
GCACAGCGACGTCCTGTTTCTGGCTGTGAAGCACATATCATCCCCTTCATCCTGGTTGAG
ATTGGGGCCGACGTGCAAGCCAGACACATCGTGGTCTCCTGTGCGGCTGGTGTTACCATC
AGCTCTGTGGAGAAGAAGCTGATGGAATTCCAGCCAGCCCCCAAAGTGATTCGCTGCATG
ACCAACACACCTGTGGTAGTGCAGGAAGGCGCTACAGTGTACGCCACGGGCACCCATGCC
CTGGTGGAGGATGGGCAGCTCCTGGAGCAGCTCATGAGCAGCGTGGGCTTCTGCACTGAG
GTGGAAGAGGACCTCATCGATGCCGTCACGGGGCTCAGTGGCAGCAAACCTGCCTATGCA
TTCATGGCTCTGGACGCATTGGCTGATGGTGGGGTGAAGATGGGTTTGCCACGGCGCCTG
GCAATCCAACTCGGGGCCCAGGCTTTGCTGGGAGCTGCCAAGATGCTGCTGGACTCGGAG
CAGCATCCATGCCAGCTTAAGGACAATGTCTGCTCCCCTGGGGGAGCCACCATCCACGCC
CTGCACTTTCTAGAGAGTGGGGGCTTCCGCTCTCTGCTCATCAATGCAGTTGAGGCCTCC
TGTATCCGAACACGAGAGCTACAGTCCATGGCCGACCAAGAAAAGATCTCCCCAGCTGCC
CTTAAGAAGACCCTCTTAGACAGAGTGAAGCTGGAATCCCCCACAGTCTCCACACTGACC
CCCTCCAGCCCAGGGAAGCTCCTCACAAGAAGCCTGGCCCTGGGAGGCAAGAAGGACTAA
Protein Properties
Number of Residues 319
Molecular Weight 33726.4
Theoretical pI 5.91
Pfam Domain Function Not Available
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Pyrroline-5-carboxylate reductase
MSVGFIGAGQLAMLWRGASRPQIPVGSQDNSQLPRNEPAHGVRAQEDGCEPDTQQQGDGE
AQRRPVSGCEAHIIPFILVEIGADVQARHIVVSCAAGVTISSVEKKLMEFQPAPKVIRCM
TNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSKPAYA
FMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHA
LHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTLT
PSSPGKLLTRSLALGGKKD
GenBank ID Protein 4960118
UniProtKB/Swiss-Prot ID Q4W8W1
UniProtKB/Swiss-Prot Entry Name Q4W8W1_HUMAN
PDB IDs Not Available
GenBank Gene ID AF151351
GeneCard ID P5CR2
GenAtlas ID P5CR2
HGNC ID HGNC:30262
References
General References Not Available