Showing Protein Sodium/potassium/calcium exchanger 3 (CDBP02267)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02267
Secondary Accession Numbers Not Available
Name Sodium/potassium/calcium exchanger 3
Description Not Available
Synonyms
  1. Na(+)/K(+)/Ca(2+)-exchange protein 3
  2. Solute carrier family 24 member 3
Gene Name SLC24A3
Protein Type Enzyme
Biological Properties
General Function Involved in transmembrane transport
Specific Function Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+)
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Process
establishment of localization
transport
transmembrane transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 20p13
SNPs SLC24A3
Gene Sequence 
>1935 bp
ATGCGGCCGTCCGGCGACGAGGACCGCGCGCGTCGCCGCCGCCGCCGCCGCCGCCGGAGG
GACCTTCTGCTGAGCCAGCTCTGCTTCCTGGCCTCGGTGGCGCTGCTGCTCTGGTCGCTG
TCGAGCCTGCGAGAGCAGAAGGAGCTTGACCTCATGGACCTCGTAGGGGAAGACAGAAAG
TGGATGATGGCGAGGAAGCTGATGCAGGTGAACGACACTCTGACTTCCGAAGATGCCGGA
CTCCGGAACAGCAAGAACTGCACCGAACCAGCCCTGCATGAATTCCCCAATGACATCTTC
ACAAACGAGGATAGAAGACAAGGTGCGGTGGTCCTCCATGTGCTCTGTGCCATATACATG
TTCTATGCGCTGGCCATTGTGTGTGATGACTTCTTCGTCCCTTCCTTGGAAAAGATCTGT
GAGCGCCTGCACCTCAGTGAAGATGTGGCTGGGGCCACATTCATGGCAGCGGGAAGTTCG
GCCCCAGAGCTGTTCACATCGGTCATAGGGGTCTTCATCACCAAAGGCGATGTGGGAGTT
GGCACCATCGTGGGCTCAGCGGTATTCAACATCCTGTGCATCATTGGTGTCTGTGGGCTC
TTTGCTGGGCAGGTTGTGGCTCTTTCCTCCTGGTGCCTGCTGAGGGATTCTATTTACTAC
ACGCTGTCTGTGATCGCGCTCATCGTGTTTATTTATGATGAAAAAGTTTCCTGGTGGGAG
TCTTTAGTCCTTGTGCTGATGTATCTTATCTACATTGTCATCATGAAATATAACGCTTGC
ATACATCAGTGCTTTGAGAGGAGGACAAAAGGTGCCGGGAACATGGTCAACGGATTGGCC
AACAATGCTGAAATTGATGACAGCAGCAACTGCGACGCAACTGTGGTGCTACTTAAGAAA
GCAAATTTCCACCGCAAAGCATCAGTGATCATGGTAGACGAGCTGCTGTCAGCCTACCCA
CACCAGCTTTCCTTCTCTGAGGCTGGCCTTCGAATCATGATAACCAGCCACTTTCCCCCC
AAGACCCGGCTCTCCATGGCCAGTCGCATGTTGATCAATGAGAGACAAAGATTGATAAAC
AGCAGGGCTTATACCAACGGGGAATCTGAGGTGGCCATCAAAATCCCAATTAAGCACACC
GTGGAGAATGGGACAGGGCCCAGCAGTGCCCCAGACAGGGGCGTGAATGGGACACGGAGG
GACGATGTTGTGGCTGAGGCTGGCAACGAAACAGAGAATGAAAATGAGGACAATGAGAAT
GATGAGGAGGAAGAGGAGGACGAGGATGATGATGAAGGACCGTACACACCATTCGACACC
CCCTCGGGTAAACTGGAAACAGTGAAATGGGCGTTCACCTGGCCGCTGAGTTTCGTCTTA
TACTTCACTGTACCCAACTGCAACAAGCCGCGCTGGGAGAAATGGTTCATGGTGACGTTT
GCTTCCTCCACGCTGTGGATCGCAGCCTTCTCCTACATGATGGTGTGGATGGTCACAATC
ATTGGTTACACCCTGGGGATTCCTGACGTCATCATGGGGATCACCTTCCTGGCTGCTGGG
ACCAGCGTGCCTGACTGCATGGCCAGCCTCATTGTGGCCAGACAAGGGATGGGGGACATG
GCTGTGTCCAACTCCATTGGGAGCAACGTGTTTGACATCCTGATTGGCCTCGGTCTCCCC
TGGGCTCTGCAGACCCTGGCTGTGGATTACGGATCCTACATCCGGCTGAATAGCAGGGGG
CTGATCTACTCCGTAGGCTTGCTCCTGGCCTCTGTTTTTGTCACGGTGTTCGGCGTCCAC
CTGAACAAGTGGCAGCTGGACAAGAAGCTGGGCTGTGGGTGCCTCCTCCTGTATGGTGTG
TTCCTGTGCTTCTCCATCATGACTGAGTTCAACGTGTTCACCTTTGTGAACCTGCCCATG
TGCGGGGACCACTGA
Protein Properties
Number of Residues 644
Molecular Weight 71991.4
Theoretical pI 4.98
Pfam Domain Function
Signals
  • ["1-44"]
Transmembrane Regions
  • ["108-128", "154-174", "183-203", "211-231", "235-255", "485-505", "511-531", "550-570", "581-601", "616-636"]
Protein Sequence 
>Sodium/potassium/calcium exchanger 3
MRPSGDEDRARRRRRRRRRRDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLVGEDRK
WMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYM
FYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGV
GTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWE
SLVLVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKK
ANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLIN
SRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDVVAEAGNETENENEDNEN
DEEEEEDEDDDEGPYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTF
ASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDM
AVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVH
LNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMCGDH
GenBank ID Protein 31563526
UniProtKB/Swiss-Prot ID Q9HC58
UniProtKB/Swiss-Prot Entry Name NCKX3_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_020689.3
GeneCard ID SLC24A3
GenAtlas ID SLC24A3
HGNC ID HGNC:10977
References
General References Not Available