Identification
HMDB Protein ID CDBP02263
Secondary Accession Numbers Not Available
Name UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter
Description Not Available
Synonyms
  1. Solute carrier family 35 member D1
  2. UDP-GlcA/UDP-GalNAc transporter
  3. UDP-galactose transporter-related protein 7
  4. UGTrel7
Gene Name SLC35D1
Protein Type Enzyme
Biological Properties
General Function Involved in UDP-glucuronic acid transmembrane transport
Specific Function Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis.
GO Classification
Biological Process
chondroitin sulfate biosynthetic process
UDP-glucuronate biosynthetic process
xenobiotic metabolic process
carbohydrate transport
Cellular Component
integral to endoplasmic reticulum membrane
Molecular Function
UDP-glucuronic acid transmembrane transporter activity
UDP-N-acetylgalactosamine transmembrane transporter activity
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location 1
Locus 1p32-p31
SNPs SLC35D1
Gene Sequence
>1068 bp
ATGGCGGAAGTTCATAGACGTCAGCATGCTCGGGTTAAAGGAGAAGCCCCCGCGAAATCC
TCCACACTCCGAGATGAGGAGGAGCTGGGGATGGCGTCGGCCGAAACGCTGACCGTGTTT
CTGAAGCTGCTGGCCGCCGGCTTTTACGGCGTGAGCTCCTTCCTGATCGTGGTGGTGAAT
AAGAGCGTGCTCACCAATTACAGATTTCCCTCCTCACTATGTGTTGGACTTGGCCAGATG
GTGGCCACAGTGGCAGTTCTCTGGGTGGGAAAGGCGCTCAGAGTAGTCAAGTTTCCTGAC
CTTGACAGAAATGTACCTCGAAAGACGTTTCCACTACCTCTACTATATTTTGGGAACCAA
ATCACGGGACTGTTCAGCACAAAGAAACTGAACTTGCCAATGTTTACAGTTCTGAGAAGG
TTCTCCATCCTGTTTACAATGTTTGCTGAAGGAGTTTTACTCAAGAAGACTTTTTCTTGG
GGTATTAAAATGACTGTATTTGCAATGATTATTGGAGCCTTTGTAGCTGCCAGCTCTGAC
TTGGCATTTGATCTGGAAGGATATGCTTTTATTCTGATAAACGATGTCCTAACAGCAGCA
AATGGTGCATACGTAAAACAAAAATTAGATTCAAAAGAGCTGGGAAAATATGGACTGCTC
TATTACAATGCACTGTTCATGATTCTGCCCACCCTGGCCATTGCGTATTTCACAGGAGAT
GCACAAAAGGCTGTGGAGTTTGAAGGCTGGGCTGACACCCTCTTTCTTCTGCAGTTCACC
CTCTCCTGTGTGATGGGGTTTATCTTAATGTACGCCACAGTACTCTGCACGCAGTATAAT
TCTGCTCTTACAACTACAATAGTTGGCTGTATTAAGAATATATTAATAACTTATATTGGA
ATGGTCTTTGGTGGAGATTATATTTTCACGTGGACAAACTTCATTGGTTTAAATATCAGC
ATTGCTGGGAGCCTGGTATATTCCTATATCACTTTCACTGAAGAGCAGCTGAGCAAACAG
TCAGAGGCTAATAACAAGCTGGACATTAAGGGGAAAGGAGCAGTGTGA
Protein Properties
Number of Residues 355
Molecular Weight 39239.8
Theoretical pI 8.964
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter
MAEVHRRQHARVKGEAPAKSSTLRDEEELGMASAETLTVFLKLLAAGFYGVSSFLIVVVN
KSVLTNYRFPSSLCVGLGQMVATVAVLWVGKALRVVKFPDLDRNVPRKTFPLPLLYFGNQ
ITGLFSTKKLNLPMFTVLRRFSILFTMFAEGVLLKKTFSWGIKMTVFAMIIGAFVAASSD
LAFDLEGYAFILINDVLTAANGAYVKQKLDSKELGKYGLLYYNALFMILPTLAIAYFTGD
AQKAVEFEGWADTLFLLQFTLSCVMGFILMYATVLCTQYNSALTTTIVGCIKNILITYIG
MVFGGDYIFTWTNFIGLNISIAGSLVYSYITFTEEQLSKQSEANNKLDIKGKGAV
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9NTN3
UniProtKB/Swiss-Prot Entry Name S35D1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB044343
GeneCard ID SLC35D1
GenAtlas ID SLC35D1
HGNC ID HGNC:20800
References
General References Not Available