Identification |
HMDB Protein ID
| CDBP02263 |
Secondary Accession Numbers
| Not Available |
Name
| UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter |
Description
| Not Available |
Synonyms
|
- Solute carrier family 35 member D1
- UDP-GlcA/UDP-GalNAc transporter
- UDP-galactose transporter-related protein 7
- UGTrel7
|
Gene Name
| SLC35D1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in UDP-glucuronic acid transmembrane transport |
Specific Function
| Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis.
|
GO Classification
|
Biological Process |
chondroitin sulfate biosynthetic process |
UDP-glucuronate biosynthetic process |
xenobiotic metabolic process |
carbohydrate transport |
Cellular Component |
integral to endoplasmic reticulum membrane |
Molecular Function |
UDP-glucuronic acid transmembrane transporter activity |
UDP-N-acetylgalactosamine transmembrane transporter activity |
|
Cellular Location
|
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 1 |
Locus
| 1p32-p31 |
SNPs
| SLC35D1 |
Gene Sequence
|
>1068 bp
ATGGCGGAAGTTCATAGACGTCAGCATGCTCGGGTTAAAGGAGAAGCCCCCGCGAAATCC
TCCACACTCCGAGATGAGGAGGAGCTGGGGATGGCGTCGGCCGAAACGCTGACCGTGTTT
CTGAAGCTGCTGGCCGCCGGCTTTTACGGCGTGAGCTCCTTCCTGATCGTGGTGGTGAAT
AAGAGCGTGCTCACCAATTACAGATTTCCCTCCTCACTATGTGTTGGACTTGGCCAGATG
GTGGCCACAGTGGCAGTTCTCTGGGTGGGAAAGGCGCTCAGAGTAGTCAAGTTTCCTGAC
CTTGACAGAAATGTACCTCGAAAGACGTTTCCACTACCTCTACTATATTTTGGGAACCAA
ATCACGGGACTGTTCAGCACAAAGAAACTGAACTTGCCAATGTTTACAGTTCTGAGAAGG
TTCTCCATCCTGTTTACAATGTTTGCTGAAGGAGTTTTACTCAAGAAGACTTTTTCTTGG
GGTATTAAAATGACTGTATTTGCAATGATTATTGGAGCCTTTGTAGCTGCCAGCTCTGAC
TTGGCATTTGATCTGGAAGGATATGCTTTTATTCTGATAAACGATGTCCTAACAGCAGCA
AATGGTGCATACGTAAAACAAAAATTAGATTCAAAAGAGCTGGGAAAATATGGACTGCTC
TATTACAATGCACTGTTCATGATTCTGCCCACCCTGGCCATTGCGTATTTCACAGGAGAT
GCACAAAAGGCTGTGGAGTTTGAAGGCTGGGCTGACACCCTCTTTCTTCTGCAGTTCACC
CTCTCCTGTGTGATGGGGTTTATCTTAATGTACGCCACAGTACTCTGCACGCAGTATAAT
TCTGCTCTTACAACTACAATAGTTGGCTGTATTAAGAATATATTAATAACTTATATTGGA
ATGGTCTTTGGTGGAGATTATATTTTCACGTGGACAAACTTCATTGGTTTAAATATCAGC
ATTGCTGGGAGCCTGGTATATTCCTATATCACTTTCACTGAAGAGCAGCTGAGCAAACAG
TCAGAGGCTAATAACAAGCTGGACATTAAGGGGAAAGGAGCAGTGTGA
|
Protein Properties |
Number of Residues
| 355 |
Molecular Weight
| 39239.8 |
Theoretical pI
| 8.964 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter
MAEVHRRQHARVKGEAPAKSSTLRDEEELGMASAETLTVFLKLLAAGFYGVSSFLIVVVN
KSVLTNYRFPSSLCVGLGQMVATVAVLWVGKALRVVKFPDLDRNVPRKTFPLPLLYFGNQ
ITGLFSTKKLNLPMFTVLRRFSILFTMFAEGVLLKKTFSWGIKMTVFAMIIGAFVAASSD
LAFDLEGYAFILINDVLTAANGAYVKQKLDSKELGKYGLLYYNALFMILPTLAIAYFTGD
AQKAVEFEGWADTLFLLQFTLSCVMGFILMYATVLCTQYNSALTTTIVGCIKNILITYIG
MVFGGDYIFTWTNFIGLNISIAGSLVYSYITFTEEQLSKQSEANNKLDIKGKGAV
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q9NTN3 |
UniProtKB/Swiss-Prot Entry Name
| S35D1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB044343 |
GeneCard ID
| SLC35D1 |
GenAtlas ID
| SLC35D1 |
HGNC ID
| HGNC:20800 |
References |
General References
| Not Available |