| Identification |
|---|
| HMDB Protein ID
| CDBP02253 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphate carrier protein, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- PTP
- Phosphate transport protein
- Solute carrier family 25 member 3
|
| Gene Name
| SLC25A3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in binding |
| Specific Function
| Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP).
|
| GO Classification
|
| Biological Process |
| generation of precursor metabolites and energy |
| Cellular Component |
| mitochondrial inner membrane |
| integral to plasma membrane |
| Component |
| membrane |
| cell part |
| Function |
| binding |
| Molecular Function |
| phosphate ion carrier activity |
| symporter activity |
| Process |
| transport |
| transmembrane transport |
| establishment of localization |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 12 |
| Locus
| 12q23 |
| SNPs
| SLC25A3 |
| Gene Sequence
|
>1089 bp
ATGTTCTCGTCCGTGGCGCACCTGGCGCGGGCGAACCCCTTCAACACGCCACATCTGCAG
CTGGTGCACGATGGTCTCGGGGACCTCCGCAGCAGCTCCCCAGGGCCCACGGGCCAGCCC
CGCCGCCCTCGCAACCTGGCAGCCGCCGCCGTGGAAGAGCAGTATAGCTGTGACTATGGA
TCTGGCAGATTCTTTATCCTTTGTGGACTTGGAGGAATTATTAGCTGTGGCACAACACAT
ACAGCATTGGTTCCTCTAGATCTGGTTAAATGCAGAATGCAGGTGGACCCCCAAAAGTAC
AAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCT
AAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTT
TATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGG
CGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTG
GCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTG
AGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTT
GCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGT
ACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCA
GAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTT
TCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCT
CTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATC
ATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTC
AGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTA
ACTCAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 362 |
| Molecular Weight
| 39958.38 |
| Theoretical pI
| 9.358 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Phosphate carrier protein, mitochondrial
MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYG
SGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA
KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL
APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER
TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS
LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL
TQ
|
| External Links |
|---|
| GenBank ID Protein
| 6031192 |
| UniProtKB/Swiss-Prot ID
| Q00325 |
| UniProtKB/Swiss-Prot Entry Name
| MPCP_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_005888.3 |
| GeneCard ID
| SLC25A3 |
| GenAtlas ID
| SLC25A3 |
| HGNC ID
| HGNC:10989 |
| References |
|---|
| General References
| Not Available |