Identification
HMDB Protein ID CDBP02245
Secondary Accession Numbers Not Available
Name ATP synthase lipid-binding protein, mitochondrial
Description Not Available
Synonyms
  1. ATP synthase proteolipid P3
  2. ATPase protein 9
  3. ATPase subunit c
Gene Name ATP5G3
Protein Type Enzyme
Biological Properties
General Function Involved in hydrogen ion transmembrane transporter activity
Specific Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element
GO Classification
Component
macromolecular complex
protein complex
proton-transporting two-sector atpase complex, proton-transporting domain
proton-transporting atp synthase complex, coupling factor f(o)
Function
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
monovalent inorganic cation transmembrane transporter activity
hydrogen ion transmembrane transporter activity
transporter activity
transmembrane transporter activity
Process
nucleoside phosphate metabolic process
nucleotide metabolic process
atp synthesis coupled proton transport
atp biosynthetic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
Cellular Location
  1. Mitochondrion membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2q31.1
SNPs ATP5G3
Gene Sequence
>429 bp
ATGTTCGCCTGCGCCAAGCTCGCCTGCACCCCCTCTCTGATCCGAGCTGGATCCAGAGTT
GCATACAGACCAATTTCTGCATCAGTGTTATCTCGACCAGAGGCTAGTAGGACTGGAGAG
GGCTCTACGGTATTTAATGGGGCCCAGAATGGTGTGTCTCAGCTAATCCAAAGGGAGTTT
CAGACCAGTGCAATCAGCAGAGACATTGATACTGCTGCCAAATTTATTGGTGCAGGTGCT
GCAACAGTAGGAGTGGCTGGTTCTGGTGCTGGTATTGGAACAGTCTTTGGCAGCCTTATC
ATTGGTTATGCCAGAAACCCTTCGCTGAAGCAGCAGCTGTTCTCATATGCTATCCTGGGA
TTTGCCTTGTCTGAAGCTATGGGTCTCTTTTGTTTGATGGTTGCTTTCTTGATTTTGTTT
GCCATGTAA
Protein Properties
Number of Residues 142
Molecular Weight 14692.9
Theoretical pI 9.77
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["83-103", "118-138"]
Protein Sequence
>ATP synthase lipid-binding protein, mitochondrial
MFACAKLACTPSLIRAGSRVAYRPISASVLSRPEASRTGEGSTVFNGAQNGVSQLIQREF
QTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILG
FALSEAMGLFCLMVAFLILFAM
GenBank ID Protein 62630225
UniProtKB/Swiss-Prot ID P48201
UniProtKB/Swiss-Prot Entry Name AT5G3_HUMAN
PDB IDs Not Available
GenBank Gene ID AC096649
GeneCard ID ATP5G3
GenAtlas ID ATP5G3
HGNC ID HGNC:843
References
General References Not Available