| Identification |
|---|
| HMDB Protein ID
| CDBP02234 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphatidylinositol-glycan biosynthesis class X protein |
| Description
| Not Available |
| Synonyms
|
- PIG-X
|
| Gene Name
| PIGX |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GPI anchor biosynthetic process |
| Specific Function
| Essential component of glycosylphosphatidylinositol- mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM |
| GO Classification
|
| Component |
| membrane |
| cell part |
| endoplasmic reticulum membrane |
| organelle membrane |
| Process |
| metabolic process |
| macromolecule metabolic process |
| protein amino acid lipidation |
| gpi anchor biosynthetic process |
| macromolecule modification |
| protein modification process |
|
| Cellular Location
|
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q29 |
| SNPs
| PIGX |
| Gene Sequence
|
>777 bp
CTGGCGGCTCGGGTGGCGGCGGTTCGGGCGGCCGCCTGGCTGCTCCTCGGGGCGGCGACC
GGGCTCACGCGCGGGCCCGCCGCGGCCTTCACCGCCGCGCGCTCTGACGCCGGCATAAGG
GCCATGTGTTCTGAAATTATTTTGAGGCAAGAAGTTTTGAAAGATGGTTTCCACAGAGAC
CTTTTAATCAAAGTGAAGTTTGGGGAAAGCATTGAGGACTTGCACACCTGCCGTCTCTTA
ATTAAACAGGACATTCCTGCAGGACTTTATGTGGATCCGTATGAGTTGGCTTCATTACGA
GAGAGAAACATAACAGAGGCAGTGATGGTTTCAGAAAATTTTGATATAGAGGCCCCTAAC
TATTTGTCCAAGGAGTCTGAAGTTCTCATTTATGCCAGACGAGATTCACAGTGCATTGAC
TGTTTTCAAGCCTTTTTGCCTGTGCACTGCCGCTATCATCGGCCGCACAGTGAAGATGGA
GAAGCCTCGATTGTGGTCAATAACCCAGATTTGTTGATGTTTTGTGACCAAGAGTTCCCG
ATTTTGAAATGCTGGGCTCACTCAGAAGTGGCAGCCCCTTGTGCTTTGGAGAATGAGGAT
ATCTGCCAATGGAACAAGATGAAGTATAAATCAGTATATAAGAATGTGATTCTACAAGTT
CCAGTGGGACTGACTGTACATACCTCTCTAGTATGTTCTGTGACTCTGCTCATTACAATC
CTGTGCTCTACATTGATCCTTGTAGCAGTTTTCAAATATGGCCATTTTTCCCTATAA
|
| Protein Properties |
|---|
| Number of Residues
| 258 |
| Molecular Weight
| 28788.1 |
| Theoretical pI
| 6.3 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Phosphatidylinositol-glycan biosynthesis class X protein
MAARVAAVRAAAWLLLGAATGLTRGPAAAFTAARSDAGIRAMCSEIILRQEVLKDGFHRD
LLIKVKFGESIEDLHTCRLLIKQDIPAGLYVDPYELASLRERNITEAVMVSENFDIEAPN
YLSKESEVLIYARRDSQCIDCFQAFLPVHCRYHRPHSEDGEASIVVNNPDLLMFCDQEFP
ILKCWAHSEVAAPCALENEDICQWNKMKYKSVYKNVILQVPVGLTVHTSLVCSVTLLITI
LCSTLILVAVFKYGHFSL
|
| External Links |
|---|
| GenBank ID Protein
| 261490706 |
| UniProtKB/Swiss-Prot ID
| Q8TBF5 |
| UniProtKB/Swiss-Prot Entry Name
| PIGX_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_017861.3 |
| GeneCard ID
| PIGX |
| GenAtlas ID
| PIGX |
| HGNC ID
| HGNC:26046 |
| References |
|---|
| General References
| Not Available |