Identification |
HMDB Protein ID
| CDBP02175 |
Secondary Accession Numbers
| Not Available |
Name
| Asc-type amino acid transporter 1 |
Description
| Not Available |
Synonyms
|
- Asc-1
- Solute carrier family 7 member 10
|
Gene Name
| SLC7A10 |
Protein Type
| Transporter |
Biological Properties |
General Function
| Amino acid transport and metabolism |
Specific Function
| Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse |
GO Classification
|
Component |
membrane |
cell part |
Function |
amine transmembrane transporter activity |
amino acid transmembrane transporter activity |
transporter activity |
active transmembrane transporter activity |
transmembrane transporter activity |
Process |
establishment of localization |
transport |
amine transport |
amino acid transport |
transmembrane transport |
|
Cellular Location
|
- Membrane
- Multi-pass membrane protein (Probable)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 19q13.1 |
SNPs
| SLC7A10 |
Gene Sequence
|
>1572 bp
ATGGCCGGCCACACGCAGCAGCCGAGCGGGCGCGGGAACCCCAGGCCTGCGCCCTCGCCC
TCCCCAGTCCCAGGGACCGTCCCCGGCGCCTCGGAGCGGGTGGCGCTCAAGAAGGAGATC
GGGCTGCTGAGCGCCTGCACCATCATCATCGGGAACATCATCGGCTCGGGCATCTTCATC
TCGCCCAAGGGGGTCCTGGAGCACTCAGGCTCCGTGGGTCTGGCCCTGTTCGTCTGGGTC
CTGGGTGGGGGCGTGACGGCTCTGGGCTCCCTCTGCTATGCAGAGCTGGGAGTCGCCATC
CCCAAGTCTGGCGGGGACTACGCCTACGTCACAGAGATCTTCGGGGGCCTGGCTGGCTTT
CTGCTGCTCTGGAGCGCCGTCCTCATCATGTACCCCACCAGCCTTGCTGTCATCTCCATG
ACCTTCTCCAACTACGTGCTGCAGCCCGTGTTCCCCAACTGCATCCCCCCCACCACAGCC
TCCCGGGTGCTGTCCATGGCCTGCCTGATGCTCCTGACATGGGTGAACAGCTCCAGTGTG
CGCTGGGCCACGCGCATCCAGGACATGTTCACAGGCGGGAAGCTGCTGGCCTTGTCCCTC
ATCATCGGCGTGGGCCTTCTCCAGATCTTCCAAGGACACTTCGAGGAGCTGAGGCCCAGC
AATGCCTTTGCTTTCTGGATGACGCCCTCCGTGGGACACCTGGCCCTGGCCTTCCTCCAG
GGCTCCTTCGCCTTCAGTGGCTGGAACTTCCTCAACTATGTCACCGAGGAGATGGTTGAC
GCCCGAAAGAACCTACCTCGCGCCATCTTCATCTCCATCCCACTGGTGACCTTCGTGTAC
ACGTTCACCAACATTGCCTACTTCACGGCCATGTCCCCCCAGGAGCTGCTCTCCTCCAAT
GCGGTGGCTGTGACCTTCGGGGAGAAGCTGCTGGGCTACTTTTCTTGGGTCATGCCTGTC
TCCGTGGCTCTGTCAACCTTCGGAGGGATCAATGGTTACCTGTTCACCTACTCCAGGCTG
TGCTTCTCTGGAGCCCGCGAGGGGCACCTGCCCAGCCTGCTGGCCATGATCCACGTCAGA
CACTGCACCCCCATCCCCGCCCTCCTCGTCTGTTGCGGGGCCACAGCCGTCATCATGCTC
GTGGGCGACACGTACACGCTCATCAACTATGTGTCCTTCATCAACTACCTCTGCTACGGC
GTCACCATCCTGGGCCTGCTGCTGCTGCGCTGGAGGCGGCCTGCACTCCACAGGCCCATC
AAGGTGAACCTTCTCATCCCCGTGGCGTACTTGGTCTTCTGGGCCTTCCTGCTGGTCTTC
AGCTTCATCTCAGAGCCTATGGTCTGTGGGGTCGGCGTCATCATCATCCTTACGGGGGTG
CCCATTTTCTTTCTGGGAGTGTTCTGGAGAAGCAAACCAAAGTGTGTGCACAGACTCACA
GAGTCCATGACACACTGGGGCCAGGAGCTGTGTTTCGTGGTCTACCCCCAGGACGCCCCC
GAAGAGGAGGAGAATGGCCCCTGCCCACCCTCCCTGCTGCCTGCCACAGACAAGCCCTCG
AAGCCACAATGA
|
Protein Properties |
Number of Residues
| 523 |
Molecular Weight
| 56797.4 |
Theoretical pI
| 8.24 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
- ["40-60", "72-92", "113-133", "268-288", "310-330", "362-382", "388-408", "424-444", "448-468"]
|
Protein Sequence
|
>Asc-type amino acid transporter 1
MAGHTQQPSGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFI
SPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGF
LLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSV
RWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQ
GSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSN
AVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVR
HCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPI
KVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLT
ESMTHWGQELCFVVYPQDAPEEEENGPCPPSLLPATDKPSKPQ
|
External Links |
GenBank ID Protein
| 9309293 |
UniProtKB/Swiss-Prot ID
| Q9NS82 |
UniProtKB/Swiss-Prot Entry Name
| AAA1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB037670 |
GeneCard ID
| SLC7A10 |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |