Identification
HMDB Protein ID CDBP02175
Secondary Accession Numbers Not Available
Name Asc-type amino acid transporter 1
Description Not Available
Synonyms
  1. Asc-1
  2. Solute carrier family 7 member 10
Gene Name SLC7A10
Protein Type Transporter
Biological Properties
General Function Amino acid transport and metabolism
Specific Function Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse
GO Classification
Component
membrane
cell part
Function
amine transmembrane transporter activity
amino acid transmembrane transporter activity
transporter activity
active transmembrane transporter activity
transmembrane transporter activity
Process
establishment of localization
transport
amine transport
amino acid transport
transmembrane transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19q13.1
SNPs SLC7A10
Gene Sequence
>1572 bp
ATGGCCGGCCACACGCAGCAGCCGAGCGGGCGCGGGAACCCCAGGCCTGCGCCCTCGCCC
TCCCCAGTCCCAGGGACCGTCCCCGGCGCCTCGGAGCGGGTGGCGCTCAAGAAGGAGATC
GGGCTGCTGAGCGCCTGCACCATCATCATCGGGAACATCATCGGCTCGGGCATCTTCATC
TCGCCCAAGGGGGTCCTGGAGCACTCAGGCTCCGTGGGTCTGGCCCTGTTCGTCTGGGTC
CTGGGTGGGGGCGTGACGGCTCTGGGCTCCCTCTGCTATGCAGAGCTGGGAGTCGCCATC
CCCAAGTCTGGCGGGGACTACGCCTACGTCACAGAGATCTTCGGGGGCCTGGCTGGCTTT
CTGCTGCTCTGGAGCGCCGTCCTCATCATGTACCCCACCAGCCTTGCTGTCATCTCCATG
ACCTTCTCCAACTACGTGCTGCAGCCCGTGTTCCCCAACTGCATCCCCCCCACCACAGCC
TCCCGGGTGCTGTCCATGGCCTGCCTGATGCTCCTGACATGGGTGAACAGCTCCAGTGTG
CGCTGGGCCACGCGCATCCAGGACATGTTCACAGGCGGGAAGCTGCTGGCCTTGTCCCTC
ATCATCGGCGTGGGCCTTCTCCAGATCTTCCAAGGACACTTCGAGGAGCTGAGGCCCAGC
AATGCCTTTGCTTTCTGGATGACGCCCTCCGTGGGACACCTGGCCCTGGCCTTCCTCCAG
GGCTCCTTCGCCTTCAGTGGCTGGAACTTCCTCAACTATGTCACCGAGGAGATGGTTGAC
GCCCGAAAGAACCTACCTCGCGCCATCTTCATCTCCATCCCACTGGTGACCTTCGTGTAC
ACGTTCACCAACATTGCCTACTTCACGGCCATGTCCCCCCAGGAGCTGCTCTCCTCCAAT
GCGGTGGCTGTGACCTTCGGGGAGAAGCTGCTGGGCTACTTTTCTTGGGTCATGCCTGTC
TCCGTGGCTCTGTCAACCTTCGGAGGGATCAATGGTTACCTGTTCACCTACTCCAGGCTG
TGCTTCTCTGGAGCCCGCGAGGGGCACCTGCCCAGCCTGCTGGCCATGATCCACGTCAGA
CACTGCACCCCCATCCCCGCCCTCCTCGTCTGTTGCGGGGCCACAGCCGTCATCATGCTC
GTGGGCGACACGTACACGCTCATCAACTATGTGTCCTTCATCAACTACCTCTGCTACGGC
GTCACCATCCTGGGCCTGCTGCTGCTGCGCTGGAGGCGGCCTGCACTCCACAGGCCCATC
AAGGTGAACCTTCTCATCCCCGTGGCGTACTTGGTCTTCTGGGCCTTCCTGCTGGTCTTC
AGCTTCATCTCAGAGCCTATGGTCTGTGGGGTCGGCGTCATCATCATCCTTACGGGGGTG
CCCATTTTCTTTCTGGGAGTGTTCTGGAGAAGCAAACCAAAGTGTGTGCACAGACTCACA
GAGTCCATGACACACTGGGGCCAGGAGCTGTGTTTCGTGGTCTACCCCCAGGACGCCCCC
GAAGAGGAGGAGAATGGCCCCTGCCCACCCTCCCTGCTGCCTGCCACAGACAAGCCCTCG
AAGCCACAATGA
Protein Properties
Number of Residues 523
Molecular Weight 56797.4
Theoretical pI 8.24
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["40-60", "72-92", "113-133", "268-288", "310-330", "362-382", "388-408", "424-444", "448-468"]
Protein Sequence
>Asc-type amino acid transporter 1
MAGHTQQPSGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFI
SPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGF
LLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSV
RWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQ
GSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSN
AVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVR
HCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPI
KVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLT
ESMTHWGQELCFVVYPQDAPEEEENGPCPPSLLPATDKPSKPQ
GenBank ID Protein 9309293
UniProtKB/Swiss-Prot ID Q9NS82
UniProtKB/Swiss-Prot Entry Name AAA1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB037670
GeneCard ID SLC7A10
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available