| Identification |
|---|
| HMDB Protein ID
| CDBP02163 |
| Secondary Accession Numbers
| Not Available |
| Name
| Synaptosomal-associated protein 25 |
| Description
| Not Available |
| Synonyms
|
- SNAP-25
- SUP
- Super protein
- Synaptosomal-associated 25 kDa protein
|
| Gene Name
| SNAP25 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in neurotransmitter uptake |
| Specific Function
| t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasm
- perinuclear region
- Cell junction
- synapse
- synaptosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 20p12-p11.2 |
| SNPs
| SNAP25 |
| Gene Sequence
|
>621 bp
ATGGCCGAAGACGCAGACATGCGCAATGAGCTGGAGGAGATGCAGCGAAGGGCTGACCAG
TTGGCTGATGAGTCGCTGGAAAGCACCCGTCGTATGCTGCAACTGGTTGAAGAGAGTAAA
GATGCTGGTGTCAGGACTTTGGTTATGTTGGATGAACAAGGAGAACAACTGGAACGCATT
GAGGAAGGGATGGACCAAATCAATAAGGACATGAAAGAAGCAGAAAAGAATTTGACGGAC
CTAGGAAAATTCTGCGGGCTTTGTGTGTGTCCCTGTAACAAGCTTAAATCAAGTGATGCT
TACAAAAAAGCCTGGGGCAATAATCAGGACGGAGTGGTGGCCAGCCAGCCTGCTCGTGTA
GTGGACGAACGGGAGCAGATGGCCATCAGTGGCGGCTTCATCCGCAGGGTAACAAATGAT
GCCCGAGAAAATGAAATGGATGAAAACCTAGAGCAGGTGAGCGGCATCATCGGGAACCTC
CGTCACATGGCCCTGGATATGGGCAATGAGATCGATACACAGAATCGCCAGATCGACAGG
ATCATGGAGAAGGCTGATTCCAACAAAACCAGAATTGATGAGGCCAACCAACGTGCAACA
AAGATGCTGGGAAGTGGTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 206 |
| Molecular Weight
| 23314.9 |
| Theoretical pI
| 4.39 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Synaptosomal-associated protein 25
MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERI
EEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARV
VDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDR
IMEKADSNKTRIDEANQRATKMLGSG
|
| External Links |
|---|
| GenBank ID Protein
| 62898966 |
| UniProtKB/Swiss-Prot ID
| P60880 |
| UniProtKB/Swiss-Prot Entry Name
| SNP25_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AK223617 |
| GeneCard ID
| SNAP25 |
| GenAtlas ID
| SNAP25 |
| HGNC ID
| HGNC:11132 |
| References |
|---|
| General References
| Not Available |