Identification
HMDB Protein ID CDBP02155
Secondary Accession Numbers Not Available
Name Solute carrier family 15 member 2
Description Not Available
Synonyms
  1. Kidney H(+)/peptide cotransporter
  2. Oligopeptide transporter, kidney isoform
  3. Peptide transporter 2
Gene Name SLC15A2
Protein Type Transporter
Biological Properties
General Function Involved in transporter activity
Specific Function Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides
GO Classification
Component
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
peptide transporter activity
oligopeptide transporter activity
transporter activity
substrate-specific transporter activity
Process
peptide transport
oligopeptide transport
establishment of localization
transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:3
Locus 3q13.33
SNPs SLC15A2
Gene Sequence
>2190 bp
ATGAATCCTTTCCAGAAAAATGAGTCCAAGGAAACTCTTTTTTCACCTGTCTCCATTGAA
GAGGTACCACCTCGACCACCTAGCCCTCCAAAGAAGCCATCTCCGACAATCTGTGGCTCC
AACTATCCACTGAGCATTGCCTTCATTGTGGTGAATGAATTCTGCGAGCGCTTTTCCTAT
TATGGAATGAAAGCTGTGCTGATCCTGTATTTCCTGTATTTCCTGCACTGGAATGAAGAT
ACCTCCACATCTATATACCATGCCTTCAGCAGCCTCTGTTATTTTACTCCCATCCTGGGA
GCAGCCATTGCTGACTCGTGGTTGGGAAAATTCAAGACAATCATCTATCTCTCCTTGGTG
TATGTGCTTGGCCATGTGATCAAGTCCTTGGGTGCCTTACCAATACTGGGAGGACAAGTG
GTACACACAGTCCTATCATTGATCGGCCTGAGTCTAATAGCTTTGGGGACAGGAGGCATC
AAACCCTGTGTGGCAGCTTTTGGTGGAGACCAGTTTGAAGAAAAACATGCAGAGGAACGG
ACTAGATACTTCTCAGTCTTCTACCTGTCCATCAATGCAGGGAGCTTGATTTCTACATTT
ATCACACCCATGCTGAGAGGAGATGTGCAATGTTTTGGAGAAGACTGCTATGCATTGGCT
TTTGGAGTTCCAGGACTGCTCATGGTAATTGCACTTGTTGTGTTTGCAATGGGAAGCAAA
ATATACAATAAACCACCCCCTGAAGGAAACATAGTGGCTCAAGTTTTCAAATGTATCTGG
TTTGCTATTTCCAATCGTTTCAAGAACCGTTCTGGAGACATTCCAAAGCGACAGCACTGG
CTAGACTGGGCGGCTGAGAAATATCCAAAGCAGCTCATTATGGATGTAAAGGCACTGACC
AGGGTACTATTCCTTTATATCCCATTGCCCATGTTCTGGGCTCTTTTGGATCAGCAGGGT
TCACGATGGACTTTGCAAGCCATCAGGATGAATAGGAATTTGGGGTTTTTTGTGCTTCAG
CCGGACCAGATGCAGGTTCTAAATCCCCTTCTGGTTCTTATCTTCATCCCGTTGTTTGAC
TTTGTCATTTATCGTCTGGTCTCCAAGTGTGGAATTAACTTCTCATCACTTAGGAAAATG
GCTGTTGGTATGATCCTAGCATGCCTGGCATTTGCAGTTGCGGCAGCTGTAGAGATAAAA
ATAAATGAAATGGCCCCAGCCCAGCCAGGTCCCCAGGAGGTTTTCCTACAAGTCTTGAAT
CTGGCAGATGATGAGGTGAAGGTGACAGTGGTGGGAAATGAAAACAATTCTCTGTTGATA
GAGTCCATCAAATCCTTTCAGAAAACACCACACTATTCCAAACTGCACCTGAAAACAAAA
AGCCAGGATTTTCACTTCCACCTGAAATATCACAATTTGTCTCTCTACACTGAGCATTCT
GTGCAGGAGAAGAACTGGTACAGTCTTGTCATTCGTGAAGATGGGAACAGTATCTCCAGC
ATGATGGTAAAGGATACAGAAAGCAGAACAACCAATGGGATGACAACCGTGAGGTTTGTT
AACACTTTGCATAAAGATGTCAACATCTCCCTGAGTACAGATACCTCTCTCAATGTTGGT
GAAGACTATGGTGTGTCTGCTTATAGAACTGTGCAAAGAGGAGAATACCCTGCAGTGCAC
TGTAGAACAGAAGATAAGAACTTTTCTCTGAATTTGGGTCTTCTAGACTTTGGTGCAGCA
TATCTGTTTGTTATTACTAATAACACCAATCAGGGTCTTCAGGCCTGGAAGATTGAAGAC
ATTCCAGCCAACAAAATGTCCATTGCGTGGCAGCTACCACAATATGCCCTGGTTACAGCT
GGGGAGGTCATGTTCTCTGTCACAGGTCTTGAGTTTTCTTATTCTCAGGCTCCCTCTAGC
ATGAAATCTGTGCTCCAGGCAGCTTGGCTATTGACAATTGCAGTTGGGAATATCATCGTG
CTTGTTGTGGCACAGTTCAGTGGCCTGGTACAGTGGGCCGAATTCATTTTGTTTTCCTGC
CTCCTGCTGGTGATCTGCCTGATCTTCTCCATCATGGGCTACTACTATGTTCCTGTAAAG
ACAGAGGATATGCGGGGTCCAGCAGATAAGCACATTCCTCACATCCAGGGGAACATGATC
AAACTAGAGACCAAGAAGACAAAACTCTGA
Protein Properties
Number of Residues 729
Molecular Weight 81782.8
Theoretical pI 8.27
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["58-78", "88-108", "115-135", "140-160", "184-204", "218-238", "296-316", "344-364", "381-401", "568-588", "612-632", "644-664", "675-695"]
Protein Sequence
>Solute carrier family 15 member 2
MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSY
YGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLV
YVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEER
TRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSK
IYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALT
RVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFD
FVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLN
LADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHS
VQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVG
EDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIED
IPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIV
LVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMI
KLETKKTKL
GenBank ID Protein 158260663
UniProtKB/Swiss-Prot ID Q16348
UniProtKB/Swiss-Prot Entry Name S15A2_HUMAN
PDB IDs Not Available
GenBank Gene ID AK289820
GeneCard ID SLC15A2
GenAtlas ID SLC15A2
HGNC ID HGNC:10921
References
General References Not Available