Identification |
HMDB Protein ID
| CDBP02155 |
Secondary Accession Numbers
| Not Available |
Name
| Solute carrier family 15 member 2 |
Description
| Not Available |
Synonyms
|
- Kidney H(+)/peptide cotransporter
- Oligopeptide transporter, kidney isoform
- Peptide transporter 2
|
Gene Name
| SLC15A2 |
Protein Type
| Transporter |
Biological Properties |
General Function
| Involved in transporter activity |
Specific Function
| Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides |
GO Classification
|
Component |
membrane |
cell part |
membrane part |
intrinsic to membrane |
integral to membrane |
Function |
peptide transporter activity |
oligopeptide transporter activity |
transporter activity |
substrate-specific transporter activity |
Process |
peptide transport |
oligopeptide transport |
establishment of localization |
transport |
|
Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:3 |
Locus
| 3q13.33 |
SNPs
| SLC15A2 |
Gene Sequence
|
>2190 bp
ATGAATCCTTTCCAGAAAAATGAGTCCAAGGAAACTCTTTTTTCACCTGTCTCCATTGAA
GAGGTACCACCTCGACCACCTAGCCCTCCAAAGAAGCCATCTCCGACAATCTGTGGCTCC
AACTATCCACTGAGCATTGCCTTCATTGTGGTGAATGAATTCTGCGAGCGCTTTTCCTAT
TATGGAATGAAAGCTGTGCTGATCCTGTATTTCCTGTATTTCCTGCACTGGAATGAAGAT
ACCTCCACATCTATATACCATGCCTTCAGCAGCCTCTGTTATTTTACTCCCATCCTGGGA
GCAGCCATTGCTGACTCGTGGTTGGGAAAATTCAAGACAATCATCTATCTCTCCTTGGTG
TATGTGCTTGGCCATGTGATCAAGTCCTTGGGTGCCTTACCAATACTGGGAGGACAAGTG
GTACACACAGTCCTATCATTGATCGGCCTGAGTCTAATAGCTTTGGGGACAGGAGGCATC
AAACCCTGTGTGGCAGCTTTTGGTGGAGACCAGTTTGAAGAAAAACATGCAGAGGAACGG
ACTAGATACTTCTCAGTCTTCTACCTGTCCATCAATGCAGGGAGCTTGATTTCTACATTT
ATCACACCCATGCTGAGAGGAGATGTGCAATGTTTTGGAGAAGACTGCTATGCATTGGCT
TTTGGAGTTCCAGGACTGCTCATGGTAATTGCACTTGTTGTGTTTGCAATGGGAAGCAAA
ATATACAATAAACCACCCCCTGAAGGAAACATAGTGGCTCAAGTTTTCAAATGTATCTGG
TTTGCTATTTCCAATCGTTTCAAGAACCGTTCTGGAGACATTCCAAAGCGACAGCACTGG
CTAGACTGGGCGGCTGAGAAATATCCAAAGCAGCTCATTATGGATGTAAAGGCACTGACC
AGGGTACTATTCCTTTATATCCCATTGCCCATGTTCTGGGCTCTTTTGGATCAGCAGGGT
TCACGATGGACTTTGCAAGCCATCAGGATGAATAGGAATTTGGGGTTTTTTGTGCTTCAG
CCGGACCAGATGCAGGTTCTAAATCCCCTTCTGGTTCTTATCTTCATCCCGTTGTTTGAC
TTTGTCATTTATCGTCTGGTCTCCAAGTGTGGAATTAACTTCTCATCACTTAGGAAAATG
GCTGTTGGTATGATCCTAGCATGCCTGGCATTTGCAGTTGCGGCAGCTGTAGAGATAAAA
ATAAATGAAATGGCCCCAGCCCAGCCAGGTCCCCAGGAGGTTTTCCTACAAGTCTTGAAT
CTGGCAGATGATGAGGTGAAGGTGACAGTGGTGGGAAATGAAAACAATTCTCTGTTGATA
GAGTCCATCAAATCCTTTCAGAAAACACCACACTATTCCAAACTGCACCTGAAAACAAAA
AGCCAGGATTTTCACTTCCACCTGAAATATCACAATTTGTCTCTCTACACTGAGCATTCT
GTGCAGGAGAAGAACTGGTACAGTCTTGTCATTCGTGAAGATGGGAACAGTATCTCCAGC
ATGATGGTAAAGGATACAGAAAGCAGAACAACCAATGGGATGACAACCGTGAGGTTTGTT
AACACTTTGCATAAAGATGTCAACATCTCCCTGAGTACAGATACCTCTCTCAATGTTGGT
GAAGACTATGGTGTGTCTGCTTATAGAACTGTGCAAAGAGGAGAATACCCTGCAGTGCAC
TGTAGAACAGAAGATAAGAACTTTTCTCTGAATTTGGGTCTTCTAGACTTTGGTGCAGCA
TATCTGTTTGTTATTACTAATAACACCAATCAGGGTCTTCAGGCCTGGAAGATTGAAGAC
ATTCCAGCCAACAAAATGTCCATTGCGTGGCAGCTACCACAATATGCCCTGGTTACAGCT
GGGGAGGTCATGTTCTCTGTCACAGGTCTTGAGTTTTCTTATTCTCAGGCTCCCTCTAGC
ATGAAATCTGTGCTCCAGGCAGCTTGGCTATTGACAATTGCAGTTGGGAATATCATCGTG
CTTGTTGTGGCACAGTTCAGTGGCCTGGTACAGTGGGCCGAATTCATTTTGTTTTCCTGC
CTCCTGCTGGTGATCTGCCTGATCTTCTCCATCATGGGCTACTACTATGTTCCTGTAAAG
ACAGAGGATATGCGGGGTCCAGCAGATAAGCACATTCCTCACATCCAGGGGAACATGATC
AAACTAGAGACCAAGAAGACAAAACTCTGA
|
Protein Properties |
Number of Residues
| 729 |
Molecular Weight
| 81782.8 |
Theoretical pI
| 8.27 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
- ["58-78", "88-108", "115-135", "140-160", "184-204", "218-238", "296-316", "344-364", "381-401", "568-588", "612-632", "644-664", "675-695"]
|
Protein Sequence
|
>Solute carrier family 15 member 2
MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSY
YGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLV
YVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEER
TRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSK
IYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALT
RVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFD
FVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLN
LADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHS
VQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVG
EDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIED
IPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIV
LVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMI
KLETKKTKL
|
External Links |
GenBank ID Protein
| 158260663 |
UniProtKB/Swiss-Prot ID
| Q16348 |
UniProtKB/Swiss-Prot Entry Name
| S15A2_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AK289820 |
GeneCard ID
| SLC15A2 |
GenAtlas ID
| SLC15A2 |
HGNC ID
| HGNC:10921 |
References |
General References
| Not Available |