Cannabis Compound Database: Showing Protein Selenocysteine-specific elongation factor (CDBP02153)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP02153

Secondary Accession Numbers

Not Available

Name

Selenocysteine-specific elongation factor

Description

Not Available

Synonyms

Elongation factor sec
Eukaryotic elongation factor, selenocysteine-tRNA-specific

Gene Name

EEFSEC

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTPase activity

Specific Function

Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP

GO Classification

Function
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity

Cellular Location

Cytoplasm (Potential)
Nucleus (Potential)

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:3

Locus

3q21.3

SNPs

EEFSEC

Gene Sequence

>1791 bp
ATGGCAGGGCGGCGGGTGAACGTGAACGTGGGCGTGCTGGGCCACATCGACAGCGGCAAG
ACGGCGCTGGCGCGGGCGCTAAGCACCACAGCCTCCACCGCCGCCTTTGACAAGCAGCCG
CAGAGCCGCGAGCGCGGCATCACGCTCGATCTGGGCTTCTCGTGCTTCTCGGTGCCGCTG
CCCGCGCGCCTGCGGTCGTCTTTGCCCGAGTTCCAGGCAGCGCCCGAGGCCGAGCCCGAG
CCCGGCGAGCCACTGCTTCAGGTCACGCTGGTCGACTGCCCCGGGCACGCCTCCCTCATC
CGGACCATCATCGGCGGGGCCCAGATCATTGATCTGATGATGCTGGTCATCGATGTGACC
AAGGGGATGCAGACCCAGTCAGCGGAATGCCTTGTGATCGGCCAGATTGCCTGCCAGAAG
CTGGTCGTGGTGCTGAACAAAATAGACCTCTTACCTGAAGGAAAGAGACAGGCAGCAATT
GATAAAATGACCAAGAAAATGCAGAAGACCCTAGAGAACACCAAGTTCCGAGGTGCACCG
ATTATACCCGTGGCGGCCAAGCCGGGGGGACCAGAGGCCCCCGAAACTGAAGCTCCACAG
GGCATTCCAGAGCTCATTGAGCTCCTGACGTCCCAGATTTCCATCCCAACGAGAGACCCC
TCGGGACCGTTCCTCATGTCTGTGGACCACTGTTTCTCCATCAAAGGCCAAGGCACTGTG
ATGACAGGGACCATCCTTTCAGGCTCCATCAGCCTCGGTGACAGTGTGGAGATCCCTGCC
CTCAAGGTGGTGAAGAAGGTGAAGTCCATGCAGATGTTCCACATGCCCATCACTTCAGCC
ATGCAAGGAGACCGGCTGGGCATCTGCGTCACCCAGTTTGACCCTAAGCTGCTGGAGCGC
GGGTTGGTGTGTGCCCCCGAGTCCCTGCACACTGTCCATGCGGCCCTCATCTCTGTGGAA
AAGATACCGTATTTCCGGGGGCCCCTGCAAACCAAGGCCAAGTTCCACATTACAGTGGGC
CATGAAACAGTCATGGGCCGGTTGATGTTCTTCAGTCCTGCTCCAGATAACTTTGACCAG
GAGCCTATACTGGACTCTTTCAACTTCTCTCAAGAATACCTTTTCCAGGAGCAGTACCTG
TCCAAGGATTTGACACCAGCAGTGACAGACAATGATGAGGCCGACAAGAAGGCCGGCCAG
GCCACAGAGGGCCATTGTCCTCGGCAGCAGTGGGCCCTGGTGGAGTTTGAGAAGCCCGTC
ACCTGCCCTCGGCTGTGCCTGGTGATTGGCTCCAGGCTAGATGCGGACATTCACACCAAC
ACGTGCCGGCTAGCCTTCCATGGCATCCTGCTCCACGGGCTAGAGGACAGGAACTACGCC
GACAGCTTCCTGCCCAGGCTGAAGGTGTACAAGCTGAAGCACAAGCATGGCCTTGTGGAG
CGGGCGATGGATGACTACAGTGTGATCGGCCGCTCCCTGTTCAAAAAGGAAACCAACATC
CAGCTCTTCGTGGGGCTCAAGGTGCACTTGTCCACTGGGGAACTGGGCATCATCGACAGT
GCCTTCGGCCAGAGCGGCAAGTTCAAGATCCACATCCCAGGTGGCCTCAGCCCCGAGTCC
AAGAAGATCCTGACACCCGCCCTCAAGAAGCGGGCCCGGGCTGGCCGTGGGGAGGCCACC
AGGCAGGAGGAGAGCGCCGAGCGGAGCGAGCCCTCACAGCATGTGGTGCTCAGCCTGACT
TTCAAGCGTTATGTCTTCGACACCCACAAGCGCATGGTTCAGTCTCCCTGA

Protein Properties

Number of Residues

596

Molecular Weight

65304.1

Theoretical pI

8.48

Pfam Domain Function

GTP_EFTU (PF00009 )
GTP_EFTU_D2 (PF03144 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Selenocysteine-specific elongation factor
MAGRRVNVNVGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGFSCFSVPL
PARLRSSLPEFQAAPEAEPEPGEPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVT
KGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAP
IIPVAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTV
MTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLER
GLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQ
EPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPV
TCPRLCLVIGSRLDADIHTNTCRLAFHGILLHGLEDRNYADSFLPRLKVYKLKHKHGLVE
RAMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPES
KKILTPALKKRARAGRGEATRQEESAERSEPSQHVVLSLTFKRYVFDTHKRMVQSP

External Links

GenBank ID Protein

54607086

UniProtKB/Swiss-Prot ID

P57772

UniProtKB/Swiss-Prot Entry Name

SELB_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_021937.3

GeneCard ID